You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human ATR antibody for Western Blotting

Recommended ATR Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia and Rad3 Related (ATR) Antibodies
  • ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED
  • ATATR
  • Ataxia telangiectasia-mutated and RAD3-related
  • ATR
  • ATRAD3
  • FCTCS
  • frp1
  • FRP1
  • MEC1
  • mec1
  • MHK7.5
  • MHK7_5
  • SCKL
  • sckl
  • SCKL1
  • sckl1
  • si:dkey-231j24.1
  • XATR
Reactivity
Human
8
5
2
1
1
1
1
1
1
Host
Mouse
7
1
Clonality
Monoclonal
Application
Western Blotting (WB)
5
2
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN1449281
$ 357.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.13341247 ABIN152203 WB Rabbit Log in to see
0.0011728023 ABIN401401 EIA WB Rabbit IgG Internal Region Log in to see Polyclonal 5
0.0011728023 ABIN121491 WB Rabbit AA 2122-2380 Log in to see Polyclonal
0.0011728023 ABIN121489 WB Rabbit AA 2381-2644 Log in to see Polyclonal
0.0011728023 ABIN190040 WB Rabbit Log in to see Polyclonal
0.0011728023 ABIN190039 WB Rabbit Log in to see Polyclonal

Top referenced anti-ATR antibody for Western Blotting

Similar anti-ATR Antibodies

Application / Reactivity Human
Enzyme Immunoassay (EIA) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies
Western Blotting (WB) 7 Antibodies

General

Antigen Ataxia Telangiectasia and Rad3 Related (ATR) Antibodies
Reactivity Human
(8), (5), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(7), (1)
Clonality (Clone)
Monoclonal   ( )
Application Western Blotting (WB)
(5), (2), (2)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-ATR Antibody

Target Details ATR Application Details Handling References for anti-ATR Antibody (ABIN1449281) Images
Sequence CPCELEHSIK PLFQHSPGDS SQED
Specificity This antibody reacts with human ATR.
Purification Protein A agarose
Immunogen Carrier protein (CP) conjugated synthetic peptide
Clone 4D7
Isotype IgG1

Target Details ATR

Product Details anti-ATR Antibody Application Details Handling References for anti-ATR Antibody (ABIN1449281) Images back to top
Antigen
Alternative Name ATR / FRP1 (ATR Antibody Abstract)
Background ATR (ataxia telangiectasia and Rad-3-related) is one of the most important checkpoint proteins in mammalian cells responding to DNA damage. ATR is a member of the phosphatidylinositol kinase-related protein family that includes ATM (ataxia telangiectasia mutated). These kinases are essential for signaling the presence of DNA damage or replication blocks and activating cell cycle checkpoints. It is reported that checkpoint kinase 1 (CHK1), RAD9, RAD17, Histone H2AX, p53, and BRCA1 are phosphorylated in response to genotoxic stress in an ATR-dependent manner. ATR also phosphorylates ATR-interacting protein (ATRIP) that regulates ATR expression, and is an essential component of the DNA damage checkpoint signaling pathways. In addition, homozygous deletion of ATR in mice causes early embryonic lethality, suggesting that ATR has essential functions during development.Synonyms: Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1, Serine/threonine-protein kinase ATR
Gene ID 545
NCBI Accession NP_001175
UniProt Q13535
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATR Antibody Target Details ATR Handling References for anti-ATR Antibody (ABIN1449281) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ATR Antibody Target Details ATR Application Details References for anti-ATR Antibody (ABIN1449281) Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliqouts) at -20 °C.

References for anti-ATR Antibody (ABIN1449281)

Product Details anti-ATR Antibody Target Details ATR Application Details Handling Images back to top
Background publications

Cimprich, Shin, Keith, Schreiber: "cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 7, pp. 2850-5, 1996

Images

Product Details anti-ATR Antibody Target Details ATR Application Details Handling References for anti-ATR Antibody (ABIN1449281) back to top
Supplier Images
Western Blotting (WB) image for anti-ATR antibody (Ataxia Telangiectasia and Rad3 Related) (ABIN1449281) anti-Ataxia Telangiectasia and Rad3 Related (ATR) antibody