anti-Pig (Porcine) BAX antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • bax-A
  • xBax
  • xlbax
  • BAX
  • BCL2L4
  • BAX-ALPHA
  • bcl2-associated X protein, a
  • BCL2-associated X protein
  • Bcl2-associated X protein
  • baxa
  • bax
  • BAX
  • Bax
  • LOC100355675
Epitope
AA 60-110
107
65
30
23
21
20
15
15
13
11
11
10
10
10
8
8
5
5
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
497
220
201
89
46
35
30
27
22
9
8
8
5
3
3
2
1
1
1
1
Host
Rabbit
322
204
4
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
14
13
11
8
7
7
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
383
208
144
134
122
116
96
48
39
36
12
9
5
5
4
2
1
1
1
1
1
1
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Catalog No. ABIN725390
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN202051 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN386425 IF IHC (p) WB Mouse IgG1, kappa AA 3-16 Log in to see 2D2
1 ABIN725399 IHC (p) WB HRP Rabbit IgG AA 60-110 Log in to see Polyclonal
1 ABIN725392 IHC (p) WB Biotin Rabbit IgG AA 60-110 Log in to see Polyclonal
1 ABIN386430 IF IHC (p) WB Biotin Mouse IgG1, kappa AA 3-16 Log in to see 2D2
1 ABIN386428 IF IHC (p) WB Biotin Mouse IgG1, kappa AA 3-16 Log in to see 2D2
1 ABIN2589881 ELISA IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN2589882 ELISA ICC IF IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN2617494 ICC IF IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN386426 IF IHC (p) WB Mouse IgG1, kappa AA 3-16 Log in to see 2D2
1 ABIN386431 IF IHC (p) WB Mouse IgG1, kappa AA 3-16 Log in to see 2D2
1 ABIN2738495 ELISA FACS IF IHC (p) IP WB Mouse IgG1 Log in to see 2D2

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Epitope AA 60-110
(107), (65), (30), (23), (21), (20), (15), (15), (13), (11), (11), (10), (10), (10), (8), (8), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(497), (220), (201), (89), (46), (35), (30), (27), (22), (9), (8), (8), (5), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(322), (204), (4)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (14), (13), (11), (8), (7), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(383), (208), (144), (134), (122), (116), (96), (48), (39), (36), (12), (9), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1)
Pubmed 20 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN725390) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Bax
Isotype IgG

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN725390) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Subcellular location: Mitochondrion

Synonyms: BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX

Gene ID 581
UniProt Q07812
Research Area Cancer, Apoptosis/Necrosis
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN725390) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN725390) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-BAX antibody (ABIN725390)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

Abdel-Hamid, El-Azab, Moustafa: "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)).

Rahman, Ukiana, Uson-Lopez, Sikder, Saito, Kurasaki: "Cytotoxic effects of cadmium and zinc co-exposure in PC12 cells and the underlying mechanism." in: Chemico-biological interactions, Vol. 269, pp. 41-49, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Liu, Su, Hao, Chen, Liu, Liao, Li: "Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice." in: International journal of molecular sciences, Vol. 17, Issue 1, 2016

Aksu, Özkaraca, Kandemir, Ömür, Eldutar, Küçükler, Çomaklı: "Mitigation of paracetamol-induced reproductive damage by chrysin in male rats via reducing oxidative stress." in: Andrologia, Vol. 48, Issue 10, pp. 1145-1154, 2016

Daverey, Agrawal: "Curcumin alleviates oxidative stress and mitochondrial dysfunction in astrocytes." in: Neuroscience, Vol. 333, pp. 92-103, 2016

Yang, Lu, Guo: "Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis." in: Molecular medicine reports, Vol. 14, Issue 5, pp. 4075-4082, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

She, Zhao, Zhu, Han, Xia, Bai, Zhang, Li: "Aluminum Trichloride Disorders Bile Acid Secretion and Induces Hepatocyte Apoptosis in Rats." in: Cell biochemistry and biophysics, 2015

Huang, Zou, Shi, Zhang, Peng, Zhang, Gao, Wang, Zhang: "Electroacupuncture stimulates remodeling of extracellular matrix by inhibiting apoptosis in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 386012, 2015

Li, Zhang, Liu, Ren, Song, Rao, Takahashi, Zhou, Li, Chen: "Deficits of learning and memory in Hemojuvelin knockout mice." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, 2015

Park, Kim, Choi, Heo, Park: "New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro." in: Cellular signalling, Vol. 27, Issue 9, pp. 1831-9, 2015

He, Han, Hu, Zhang, Hua, Peng: "Canonical Wnt signaling pathway contributes to the proliferation and survival in porcine pancreatic stem cells (PSCs)." in: Cell and tissue research, Vol. 362, Issue 2, pp. 379-88, 2015

He, Song, Liu, Chen, Hua: "Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrial dysfunction in male germ cells." in: Cell proliferation, Vol. 47, Issue 2, pp. 161-71, 2014

Ye, Li, Li, Yang, Niu, Wang: "Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo." in: Journal of ethnopharmacology, Vol. 153, Issue 1, pp. 258-67, 2014

Lin, Wang, Wang, Fang, Zhang, Yang, Guo, Lin, Zhang, Wang: "Lithocarpus polystachyus REHD leaf aqueous extract inhibits human breast cancer growth in vitro and in vivo." in: Nutrition and cancer, Vol. 66, Issue 4, pp. 613-24, 2014

Zhu, Wang, Liang, Wang, Zhang, Li, Ying: "Regulation of cell transformation by Rb-controlled redox homeostasis." in: PLoS ONE, Vol. 9, Issue 7, pp. e102582, 2014

Lin, Bo, Tan, Sun, Song, Zhao, Ma, Li, Zheng, Xu: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." in: PLoS ONE, Vol. 9, Issue 11, pp. e112052, 2014

Wang, Lu, Dai, Zhang, Wang, Wei: "Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], 2014 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Qiu, Cai, Gao, Gu, Liu: "A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53." in: Cancer letters, Vol. 356, Issue 2 Pt B, pp. 910-7, 2014

Tian, Zhang, Wang, Dai, Shen, Yang, Huang: "The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25-35-induced oxidative stress and neuronal apoptosis in rats." in: Behavioural brain research, Vol. 242, pp. 1-8, 2013

Wang, Ma, Su: "NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells." in: Biological trace element research, Vol. 153, Issue 1-3, pp. 403-10, 2013 (1:100).

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN725390) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Bax Polyclo...
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Bax Polyclon...
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded rabbit brain tissue labeled with Anti-Bax Polycl...
SDS-PAGE (SDS) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) L1 rat brain, L2 mouse liver lysates probed (ABIN725390) at 1:200 in 4 °C. Followed b...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Paraformaldehyde-fixed, paraffin embedded rat lung; Antigen retrieval by boiling in s...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Bax Polyclon...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded rabbit brain tissue labeled with Anti-Bax Polycl...
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) L1 rat brain, L2 mouse liver lysates probed at 1:200 in 4˚C. Followed by conjugation...
Flow Cytometry (FACS) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Human HL-60 cells probed with Bax Polyclonal Antibody, Unconjugated (green) at 1:30 ...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Image provided by One World Lab validation program. A431 cells probed with Rabbit Ant...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Image provided by One World Lab validation program. MCF-7 cells probed with Rabbit An...