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anti-Human BBC3 antibody for Immunocytochemistry

Recommended BBC3 Antibody (supplied by: Log in to see )

Antigen
BCL2 Binding Component 3 (BBC3) Antibodies
  • BBC3
  • JFY-1
  • JFY1
  • Puma
  • PUMA
  • PUMA/JFY1
Epitope
C-Term
87
50
21
13
13
13
11
8
7
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
254
73
55
2
1
1
Host
Rabbit
226
25
13
Clonality
Polyclonal
Conjugate
This BBC3 antibody is un-conjugated
11
10
8
8
8
6
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
241
77
62
43
35
30
11
9
6
4
3
2
2
Supplier
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Catalog No. ABIN2498246
$ 535.71
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010215953 ABIN361748 ICC IF WB Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN268931 ICC IF WB Rabbit C-Term, AA 150-193 Log in to see Polyclonal 2
0.0010215953 ABIN258427 ICC FACS IF IHC (p) IHC WB Rabbit IgG C-Term Log in to see EP512Y
0.0010215953 ABIN2485945 ICC IF WB Atto 488 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485946 ICC IF WB Atto 565 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485947 ICC IF WB Atto 594 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485948 ICC IF WB Atto 633 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485944 ICC IF WB Atto 390 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485949 ICC IF WB Atto 655 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485950 ICC IF WB Atto 680 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485951 ICC IF WB Atto 700 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485953 ICC IF WB APC Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485954 ICC IF WB Biotin Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485952 ICC IF WB Alkaline Phosphatase (AP) Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485956 ICC IF WB HRP Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485958 ICC IF WB PerCP Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485955 ICC IF WB FITC Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485959 ICC IF WB PE Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485957 ICC IF WB PE-Atto 594 Rabbit C-Term Log in to see Polyclonal 3
0.0010215953 ABIN2485960 ICC IF WB Streptavidin Rabbit C-Term Log in to see Polyclonal 3

Top referenced anti-BBC3 antibody for Immunocytochemistry

Similar anti-BBC3 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 13 Antibodies 73 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 9 Antibodies
Flow Cytometry (FACS) 1 Antibodies 7 Antibodies
Immunocytochemistry (ICC) 24 Antibodies 46 Antibodies
Immunofluorescence (IF) 28 Antibodies 38 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 64 Antibodies
Immunochromatography (IC) 3 Antibodies

General

Antigen BCL2 Binding Component 3 (BBC3) Antibodies
Epitope C-Term
(87), (50), (21), (13), (13), (13), (11), (8), (7), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(254), (73), (55), (2), (1), (1)
Host Rabbit
(226), (25), (13)
Clonality
Polyclonal
Conjugate This BBC3 antibody is un-conjugated
(11), (10), (8), (8), (8), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(241), (77), (62), (43), (35), (30), (11), (9), (6), (4), (3), (2), (2)
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Product Details anti-BBC3 Antibody

Target Details BBC3 Application Details Handling Images
Predicted Reactivity Human Mouse
Characteristics Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
Purification Affinity chromatography purified via peptide column
Immunogen The immunogen for anti-PUMA antibody: antibody was raised against a synthetic peptide corresponding to 14 aa near the carboxy terminus of human PUMA-a. This sequence is identical between a and b forms of the PUMA proteins.

Target Details BBC3

Product Details anti-BBC3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PUMA (BBC3 Antibody Abstract)
Gene ID 27113
NCBI Accession NP_055232
Research Area Cancer, Apoptosis/Necrosis, Metabolism
Pathways p53 Signaling

Application Details

Product Details anti-BBC3 Antibody Target Details BBC3 Handling Images back to top
Application Notes EndoG antibody can be used for detection of EndoG by Western blot at 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Restrictions For Research Use only

Handling

Product Details anti-BBC3 Antibody Target Details BBC3 Application Details Images back to top
Handling Advice As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
Storage 4 °C
Storage Comment PUMA antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Expiry Date 12 months

Images

Product Details anti-BBC3 Antibody Target Details BBC3 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-BBC3 antibody (BCL2 Binding Component 3) (C-Term) (ABIN2498246) anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody
Western Blotting (WB) image for anti-BBC3 antibody (BCL2 Binding Component 3) (C-Term) (ABIN2498246) anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (Image 2)
Immunocytochemistry (ICC) image for anti-BBC3 antibody (BCL2 Binding Component 3) (C-Term) (ABIN2498246) anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (Image 3)