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|Antigen||V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies|
|Reactivity||Bird (Avian), Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This C-MYC antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
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Product Details anti-C-MYC AntibodyTarget Details C-MYC Application Details Handling Images
|Characteristics||Synonyms: Transcription factor p64, BHLHE39, Myc proto-oncogene protein, Class E basichelix-loop-helix protein 39|
Target Details C-MYCProduct Details anti-C-MYC Antibody Application Details Handling Images back to top
|Alternative Name||C-Myc (MYC Antibody Abstract)|
|Background||Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64 kDa and 67 kDa, the unphosphorylated form is 49 kDa.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64|
|Research Area||Transcription Factors, Cancer, Cell Cycle|
|Pathways||p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus|
Application DetailsProduct Details anti-C-MYC Antibody Target Details C-MYC Handling Images back to top
Western Blot. Immunoprecipitation (both with and without SDS). Immunohistochemistry on Frozen Sections. Myc is a labile protein, therefore preotease inhibitors should be used at all times.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-C-MYC Antibody Target Details C-MYC Application Details Images back to top
|Buffer||PBS containing 0.08 % Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
|Expiry Date||12 months|