anti-Human C-MYC antibody for Enzyme Immunoassay

Recommended C-MYC Antibody (supplied by: Log in to see )

Antigen
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies
  • LOC100136746
  • RNCMYC
  • c-myc
  • mMyc
  • AU016757
  • Myc2
  • Niard
  • Nird
  • bHLHe39
  • MYC
  • cmyc
  • zc-myc
  • MRTL
  • MYCC
  • c-Myc
  • C-MYC
  • CMYC
  • CMyc
  • v-myc myelocytomatosis viral oncogene homolog
  • myelocytomatosis oncogene
  • myelocytomatosis oncogene a
  • v-myc avian myelocytomatosis viral oncogene homolog
  • v-myc myelocytomatosis viral oncogene homolog (avian)
  • LOC100136746
  • Myc
  • myca
  • MYC
Epitope
pThr58
147
120
76
38
36
26
22
15
15
14
13
10
9
9
9
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
644
212
125
50
42
36
20
20
18
14
14
13
12
9
9
6
6
4
4
4
3
3
3
2
1
1
1
1
1
Host
Rabbit
360
296
29
15
8
1
Clonality
Polyclonal
Conjugate
This C-MYC antibody is un-conjugated
44
38
37
18
16
16
13
12
12
12
12
12
12
11
11
9
9
8
6
5
5
5
4
4
4
4
4
4
4
2
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
435
230
225
213
212
147
139
122
92
52
18
14
14
11
6
6
6
5
4
2
2
1
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Catalog No. ABIN358293
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN119683 EIA IHC (fro) IHC (p) WB HRP Mouse IgG1 C-Term Log in to see 9-00E-010 2
1 ABIN119684 EIA FACS IHC (fro) IHC (p) IP WB Mouse IgG1 C-Term Log in to see 9-00E-010 2
1 ABIN320079 EIA FACS IHC (fro) IHC (p) WB Mouse IgG1 C-Term Log in to see 9-00E-010 2
1 ABIN320077 EIA IHC (fro) IHC (p) WB Alkaline Phosphatase (AP) Mouse IgG1 C-Term Log in to see 9-00E-010 7
1 ABIN950700 EIA IHC (fro) IF WB FITC Chicken Ig Log in to see Polyclonal
1 ABIN950702 EIA IHC (fro) IF IP WB Chicken Ig Log in to see Polyclonal

Top referenced anti-C-MYC antibody for Enzyme Immunoassay

Similar anti-C-MYC Antibodies

Application / Reactivity Human
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Chromatin Immunoprecipitation (ChIP) 5 Antibodies
Cytometry by Time of Flight (CyTOF) 11 Antibodies
Dot Blot (DB) 18 Antibodies
Electrophoretic Mobility-Shift Assay (EMSA) 2 Antibodies
ELISA 191 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 197 Antibodies
Fluorescence Microscopy (FM) 2 Antibodies
Immunochromatography (IC) 14 Antibodies
Immunocytochemistry (ICC) 111 Antibodies
Immunoelectron Microscopy (IEM) 4 Antibodies
Immunofluorescence (IF) 177 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 14 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 52 Antibodies
Immunohistochemistry (IHC) 137 Antibodies

General

Antigen V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies
Epitope pThr58
(147), (120), (76), (38), (36), (26), (22), (15), (15), (14), (13), (10), (9), (9), (9), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(644), (212), (125), (50), (42), (36), (20), (20), (18), (14), (14), (13), (12), (9), (9), (6), (6), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(360), (296), (29), (15), (8), (1)
Clonality
Polyclonal
Conjugate This C-MYC antibody is un-conjugated
(44), (38), (37), (18), (16), (16), (13), (12), (12), (12), (12), (12), (12), (11), (11), (9), (9), (8), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(435), (230), (225), (213), (212), (147), (139), (122), (92), (52), (18), (14), (14), (11), (6), (6), (6), (5), (4), (2), (2), (1)
Pubmed 5 references available
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Product Details anti-C-MYC Antibody

Target Details C-MYC Application Details Handling ProductDetails: References for anti-C-MYC antibody (ABIN358293) Images
Specificity This antibody detects MYC pThr58. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
Purification Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
Isotype Ig

Target Details C-MYC

Product Details anti-C-MYC Antibody Application Details Handling ProductDetails: References for anti-C-MYC antibody (ABIN358293) Images back to top
Antigen
Alternative Name C-Myc (MYC Antibody Abstract)
Background MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
Molecular Weight 50434 Da
Gene ID 4609, 9606
UniProt P01106
Research Area Transcription Factors, Cancer, Cell Cycle
Pathways p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Application Details

Product Details anti-C-MYC Antibody Target Details C-MYC Handling ProductDetails: References for anti-C-MYC antibody (ABIN358293) Images back to top
Application Notes ELISA: 1/1,000. Dot Blot: 1/100-1/500. Western Blot: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details ProductDetails: References for anti-C-MYC antibody (ABIN358293) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-C-MYC antibody (ABIN358293)

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details Handling Images back to top
Background publications

Qi, Gregory, Li, Brousal, West, Hann: "p19ARF directly and differentially controls the functions of c-Myc independently of p53." in: Nature, Vol. 431, Issue 7009, pp. 712-7, 2004

Wilda, Busch, Klose, Keller, Woessmann, Kreuder, Harbott, Borkhardt: "Level of MYC overexpression in pediatric Burkitt's lymphoma is strongly dependent on genomic breakpoint location within the MYC locus." in: Genes, chromosomes & cancer, Vol. 41, Issue 2, pp. 178-82, 2004

Domínguez-Cáceres, García-Martínez, Calcabrini, González, Porque, León, Martín-Pérez: "Prolactin induces c-Myc expression and cell survival through activation of Src/Akt pathway in lymphoid cells." in: Oncogene, Vol. 23, Issue 44, pp. 7378-90, 2004

Pap, Nawrath, Heinrich, Bosse, Baier, Hummel, Petrow, Kuchen, Michel, Gay, Müller-Ladner, Moelling, Gay: "Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis." in: Arthritis and rheumatism, Vol. 50, Issue 9, pp. 2794-802, 2004

Ozawa, Shichiri, Fukai, Yoshimoto, Hirata: "Regulation of adrenomedullin gene transcription and degradation by the c-myc gene." in: Endocrinology, Vol. 145, Issue 9, pp. 4244-50, 2004

Images

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details Handling ProductDetails: References for anti-C-MYC antibody (ABIN358293) back to top
Supplier Images
 image for anti-C-MYC antibody (V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian)) (pThr58) (ABIN358293) anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) (pThr58) antibody