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anti-Non-Human Primate CDKN1A antibody for Western Blotting

Recommended CDKN1A Antibody (supplied by: Log in to see )

Antigen
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies
  • p21
  • cip1
  • p16Xic2
  • CCND1
  • sdi1
  • waf1
  • cap20
  • cdkn1
  • mda-6
  • p21cip1
  • CDKN1A
  • si:ch1073-48m5.2
  • Cip1
  • UV96
  • Waf1
  • CAP20
  • CDKN1
  • CIP1
  • MDA-6
  • P21
  • SDI1
  • WAF1
  • p21CIP1
  • CDKI
  • Cdkn1
  • mda6
  • p21Cip1
  • p21WAF
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • cyclin-dependent kinase inhibitor 1
  • cyclin-dependent kinase inhibitor 1A
  • cyclin-dependent kinase inhibitor 1A (P21)
  • cdkn1a
  • cki1
  • CDKN1A
  • LOC100348489
  • Cdkn1a
Reactivity
Human, Non-Human Primate
514
185
125
30
23
10
6
5
4
2
1
1
1
1
1
1
1
Host
Mouse
304
250
2
1
Clonality
Monoclonal
Conjugate
This CDKN1A antibody is un-conjugated
30
29
29
22
15
15
12
12
8
8
7
7
7
7
7
7
7
7
7
6
5
5
5
4
4
4
4
4
4
Application
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
317
203
164
158
131
91
67
60
53
30
30
13
7
6
4
2
1
1
Options
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Catalog No. ABIN94444
$ 254.10
Plus shipping costs $45.00

Top referenced anti-CDKN1A antibody for Western Blotting

Similar anti-CDKN1A Antibodies

Application / Reactivity Non-Human Primate Human
ELISA 1 Antibodies 137 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 31 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies 201 Antibodies
Western Blotting (WB) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 13 Antibodies
Dot Blot (DB) 33 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 158 Antibodies
Immunofluorescence (IF) 91 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 53 Antibodies
Immunohistochemistry (IHC) 131 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 30 Antibodies
Immunoprecipitation (IP) 59 Antibodies

General

Antigen Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies
Reactivity Human, Non-Human Primate
(514), (185), (125), (30), (23), (10), (6), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(304), (250), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CDKN1A antibody is un-conjugated
(30), (29), (29), (22), (15), (15), (12), (12), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4)
Application Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(317), (203), (164), (158), (131), (91), (67), (60), (53), (30), (30), (13), (7), (6), (4), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-CDKN1A Antibody

Target Details CDKN1A Application Details Handling References for anti-CDKN1A Antibody (ABIN94444) Images
Specificity The antibody WA-1 reacts with p21 protein (Waf1, Cip1, SDI 1), a 21 kDa tumour suppressor, which inhibits the activity of cyclin-dependent family kinases and of proliferating cell nuclear antigen.
Purification Purified from ascites by precipitation methods.
Purity > 95 % (by SDS-PAGE)
Immunogen Human p21 protein
Clone WA-1
Isotype IgG1

Target Details CDKN1A

Product Details anti-CDKN1A Antibody Application Details Handling References for anti-CDKN1A Antibody (ABIN94444) Images back to top
Antigen
Alternative Name CDKN1A (CDKN1A Antibody Abstract)
Background The tumour suppressor p21Waf1 (Wild-type p53-Activated Fragment 1, also known as Cip1, Cdk interacting protein, or SDI 1) is a cyclin-dependent kinase (Cdk) inhibitor, which is expressed by involvement of p53, Egr-1, AP2, STATs or other transcription factors upon various stimuli resulting in cell cycle arrest. Through its N-terminal domain p21Waf1 inhibits Cdk activity, whereas through the C-terminal domain it inhibits the activity of PCNA (proliferating cell nuclear antigen) to activate DNA replication. Cytosolic location of p21 counteracts its inhibitory activities.
Pathways p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy

Application Details

Product Details anti-CDKN1A Antibody Target Details CDKN1A Handling References for anti-CDKN1A Antibody (ABIN94444) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details References for anti-CDKN1A Antibody (ABIN94444) Images back to top
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-CDKN1A Antibody (ABIN94444)

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details Handling Images back to top
Background publications

Choi, Kim, Bae, Lim, Lee, Shin: "p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression." in: Cancer research, Vol. 68, Issue 5, pp. 1369-77, 2008

Keeshan, Cotter, McKenna: "Bcr-Abl upregulates cytosolic p21WAF-1/CIP-1 by a phosphoinositide-3-kinase (PI3K)-independent pathway." in: British journal of haematology, Vol. 123, Issue 1, pp. 34-44, 2003

Horký, Kuchtícková, Vojtesek, Kolár: "Induction of cell-cycle inhibitor p21 in rat ventricular myocytes during early postnatal transition from hyperplasia to hypertrophy." in: Physiological research / Academia Scientiarum Bohemoslovaca, Vol. 46, Issue 3, pp. 233-5, 1998

Waga, Hannon, Beach, Stillman: "The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA." in: Nature, Vol. 369, Issue 6481, pp. 574-8, 1994

Product cited in:

Kolár, Murray, Scott, Harrison, Vojt?sek, Dusek: "Relation of Bcl-2 expression to androgen receptor, p21WAF1/CIP1, and cyclin D1 status in prostate cancer." in: Molecular pathology : MP, Vol. 53, Issue 1, pp. 15-8, 2000

Images

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details Handling References for anti-CDKN1A Antibody (ABIN94444) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-CDKN1A antibody (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1)) (ABIN94444) Immunohistochemistry staining of colon carcinoma (paraffin-embedded sections) with an...
Immunofluorescence (IF) image for anti-CDKN1A antibody (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1)) (ABIN94444) Immunofluorescence staining of p21 in human primary fibroblasts using anti-p21 (; gre...