anti-Rat (Rattus) CDKN1A antibody for Enzyme Immunoassay

Recommended CDKN1A Antibody (supplied by: Log in to see )

Antigen
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies
  • p21
  • cip1
  • p16Xic2
  • CCND1
  • sdi1
  • waf1
  • cap20
  • cdkn1
  • mda-6
  • p21cip1
  • CDKN1A
  • si:ch1073-48m5.2
  • Cip1
  • UV96
  • Waf1
  • CAP20
  • CDKN1
  • CIP1
  • MDA-6
  • P21
  • SDI1
  • WAF1
  • p21CIP1
  • CDKI
  • Cdkn1
  • mda6
  • p21Cip1
  • p21WAF
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • cyclin-dependent kinase inhibitor 1
  • cyclin-dependent kinase inhibitor 1A
  • cyclin-dependent kinase inhibitor 1A (P21)
  • cdkn1a
  • cki1
  • CDKN1A
  • LOC100348489
  • Cdkn1a
Reactivity
Human, Mouse (Murine), Rat (Rattus)
580
183
123
30
23
9
6
5
4
2
1
1
1
1
1
1
1
1
Host
Rabbit
311
310
2
1
Clonality
Polyclonal
Conjugate
This CDKN1A antibody is un-conjugated
33
32
32
23
16
16
15
15
12
12
10
10
10
10
10
10
10
8
8
6
6
6
6
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
356
224
186
167
151
140
67
60
59
53
30
14
6
6
6
2
1
1
Supplier
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Catalog No. ABIN271762
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN318089 EIA IHC (p) WB Rabbit pThr145 Log in to see Polyclonal

General

Antigen Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(580), (183), (123), (30), (23), (9), (6), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(311), (310), (2), (1)
Clonality
Polyclonal
Conjugate This CDKN1A antibody is un-conjugated
(33), (32), (32), (23), (16), (16), (15), (15), (12), (12), (10), (10), (10), (10), (10), (10), (10), (8), (8), (6), (6), (6), (6), (4), (4), (4), (4), (4), (4)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(356), (224), (186), (167), (151), (140), (67), (60), (59), (53), (30), (14), (6), (6), (6), (2), (1), (1)
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Product Details anti-CDKN1A Antibody

Target Details CDKN1A Application Details Handling Images
Specificity This antibody detects endogenous levels of p21 Cip1 protein. (region surrounding Gly139)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details CDKN1A

Product Details anti-CDKN1A Antibody Application Details Handling Images back to top
Antigen
Alternative Name CDKN1A / p21WAF1 (CDKN1A Antibody Abstract)
Background It is now well established that cyclins play a positive role in promoting cell cycle transitions via their ability to associate with and activate their cognate cyclin-dependent kinases (Cdks). Cdk2 associates with cyclins A, D and E, and has been implicated in the control of the G1 to S phase transition in mammals. A novel Cdk-interacting protein, designated p21, Cip1 or WAF1, has been identified in cyclin A, cyclin D1, cyclin E and Cdk2 immunoprecipitates. p21 is a potent, tight-binding inhibitor of Cdks and can inhibit the phosphorylation of Rb by cyclin A-Cdk 2, cyclin E-Cdk2, cyclin D1-Cdk4 and cyclin D2-Cdk4 complexes. Expression of p21 is inducible by wildtype, but not mutant, p53. The mouse homolog of p21 is designated CAP20.Synonyms: CAP20, CDK-interacting protein 1, CDKN1, CIP1, Cyclin-dependent kinase inhibitor 1, MDA-6, MDA6, Melanoma differentiation-associated protein 6, PIC1, SDI1, WAF1
Molecular Weight approx. 21.0 kDa
Gene ID 1026
NCBI Accession NP_000380
UniProt P38936
Pathways p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy

Application Details

Product Details anti-CDKN1A Antibody Target Details CDKN1A Handling Images back to top
Application Notes ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details Handling back to top
Supplier Images
 image for anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody (ABIN271762) anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody