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anti-Dog (Canine) FAS antibody for Immunoprecipitation

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • A630082H08Rik
  • AI196731
  • ALPS1A
  • APO-1
  • APO1
  • APT1
  • CD95
  • FAS
  • FAS1
  • FASTM
  • lpr
  • TNFR6
  • Tnfrsf6
  • TNFRSF6
Epitope
AA 1-163
47
33
28
23
15
13
13
13
11
10
10
9
8
7
7
6
6
5
5
5
5
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
651
100
80
10
7
5
4
3
3
3
2
1
1
1
Host
Mouse
426
293
17
6
4
3
3
Clonality
Monoclonal
Conjugate
This FAS antibody is un-conjugated
74
64
51
33
16
8
7
6
4
4
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
340
294
213
130
103
78
61
54
49
44
23
19
12
9
7
5
4
3
3
3
3
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN967816
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008946119 ABIN967817 IHC (f) IF IP WB Mouse IgG2a, kappa AA 1-163 Log in to see 13-Fas 5

Top referenced anti-FAS antibody for Immunoprecipitation

Similar anti-FAS Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Chicken Dog (Canine)
Western Blotting (WB) 249 Antibodies 50 Antibodies 48 Antibodies 2 Antibodies 3 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies
Neutralization (Neut) 8 Antibodies 1 Antibodies
Intracellular Staining (ICS) 2 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Immunoprecipitation (IP) 100 Antibodies 9 Antibodies 9 Antibodies 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 70 Antibodies 21 Antibodies 20 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 128 Antibodies

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope AA 1-163
(47), (33), (28), (23), (15), (13), (13), (13), (11), (10), (10), (9), (8), (7), (7), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(651), (100), (80), (10), (7), (5), (4), (3), (3), (3), (2), (1), (1), (1)
Host Mouse
(426), (293), (17), (6), (4), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FAS antibody is un-conjugated
(74), (64), (51), (33), (16), (8), (7), (6), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(340), (294), (213), (130), (103), (78), (61), (54), (49), (44), (23), (19), (12), (9), (7), (5), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS Antibody (ABIN967816) Images
Cross-Reactivity Chicken, Dog (Canine), Mouse (Murine), Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human Fas aa. 1-163
Clone 13-Fas
Isotype IgG2a, kappa

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS Antibody (ABIN967816) Images back to top
Antigen
Alternative Name CD95 (FAS Antibody Abstract)
Background CD95 is a member of a family of cell surface receptors that includes tumor necrosis factor receptor (TNF-R), nerve growth factor receptor (NGF-R), CD40, CD27, CD30, and 4-1BB. Both murine and human Fas genes have been cloned and reportedly share 60% similarity in their amino acid sequences. CD95 (Fas) is a cell surface apoptosis-signaling molecule that is widely expressed in sites such as thymus, liver, heart, and ovary. Abnormalities in the Fas gene correlate with autoimmune features in mice and with unusually high levels of lymphocyte apoptosis in HIV-infected humans. Genetic studies have localized the Fas gene near the lpr (lymphoproliferation disease) locus on mouse chromosome 19 and further characterization reportedly has revealed that lpr is a mutation affecting the function of the Fas gene. This antibody is routinely tested by western blot analysis.
Synonyms: Fas, APO-1
Molecular Weight 45 kDa
Research Area Immunology, Innate Immunity, Cytokines, CD Antigens, Apoptosis/Necrosis, Death Receptors, Cancer, Growth Factors, Surface Receptors of Immune Cells
Pathways p53 Signaling, Apoptosis, TCR Signaling

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS Antibody (ABIN967816) Images back to top
Comment

Related Products: ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS Antibody (ABIN967816) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.

References for anti-FAS Antibody (ABIN967816)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Product cited in:

Rosen, Coll, Li, Filmus: "Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 40, pp. 37273-9, 2001

Zhuang, Demirs, Kochevar: "Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation." in: Oncogene, Vol. 20, Issue 46, pp. 6764-76, 2001

MacLaren, Clark, Gillespie: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." in: Oncogene, Vol. 19, Issue 51, pp. 5906-18, 2000

Arnold, Seifert, Asadullah, Volk: "Crosstalk between keratinocytes and T lymphocytes via Fas/Fas ligand interaction: modulation by cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 7140-7, 1999

Background publications

Itoh, Yonehara, Ishii, Yonehara, Mizushima, Sameshima, Hase, Seto, Nagata: "The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis." in: Cell, Vol. 66, Issue 2, pp. 233-43, 1991

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling References for anti-FAS Antibody (ABIN967816) back to top
Supplier Images
Western Blotting (WB) image for anti-FAS antibody (Fas (TNF Receptor Superfamily, Member 6)) (AA 1-163) (ABIN967816) Western blot analysis of CD95 on a Daudi cell lysate (Human B lymphoblast, ATCC CCL-2...
 image for anti-FAS antibody (Fas (TNF Receptor Superfamily, Member 6)) (AA 1-163) (ABIN967816) Immunohistochemical staining of a formalin-fixed rabbit liver section.