anti-Human FAS antibody for Immunocytochemistry

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • AI196731
  • APO1
  • APT1
  • CD95
  • TNFR6
  • Tnfrsf6
  • lpr
  • TNFRSF6
  • ALPS1A
  • APO-1
  • FAS1
  • FASTM
  • A630082H08Rik
  • FAS
  • Fas (TNF receptor superfamily member 6)
  • Fas (TNF receptor superfamily, member 6)
  • Fas cell surface death receptor
  • fatty acid synthase
  • Fas
  • FAS
  • Fasn
Reactivity
Human
646
113
99
15
11
10
6
6
3
3
3
3
2
1
Host
Mouse
414
303
24
5
4
3
3
Clonality
Monoclonal
Conjugate
This FAS antibody is un-conjugated
73
63
51
29
15
8
7
7
5
5
5
4
4
4
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
334
317
209
146
113
85
61
54
52
46
22
18
12
7
7
6
5
5
4
4
3
3
3
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN969518
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1497379 ICC FACS IF IHC ELISA WB Mouse IgG1 Log in to see 4F8H6
1 ABIN2506690 ICC IF IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN440429 FACS ICC IHC IHC (fro) IHC (p) IP FITC Mouse IgG1 Log in to see DX2
1 ABIN440430 ELISA FACS ICC IHC IHC (fro) IHC (p) IP Biotin Mouse IgG1 Log in to see DX2
1 ABIN1078008 ICC IHC IP WB Rabbit IgG AA 26-173 Log in to see Polyclonal 1
1 ABIN1858799 ICC IHC IP WB Rabbit IgG AA 22-172 Log in to see Polyclonal
1 ABIN4880717 ELISA FACS ICC WB Mouse IgG1 Log in to see 4F8H6
1 ABIN215840 FACS ICC WB Mouse IgM Log in to see CH11
1 ABIN1172023 ICC IF IHC WB FITC Rabbit IgG Log in to see Polyclonal
1 ABIN200547 ICC FACS IHC (fro) Mouse IgM Log in to see

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Reactivity Human
(646), (113), (99), (15), (11), (10), (6), (6), (3), (3), (3), (3), (2), (1)
Host Mouse
(414), (303), (24), (5), (4), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FAS antibody is un-conjugated
(73), (63), (51), (29), (15), (8), (7), (7), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(334), (317), (209), (146), (113), (85), (61), (54), (52), (46), (22), (18), (12), (7), (7), (6), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling ProductDetails: References for anti-FAS antibody (ABIN969518) Images
Purification Purified
Immunogen Purified recombinant fragment of human FAS expressed in E. Coli.
Clone 4F8H6
Isotype IgG1

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling ProductDetails: References for anti-FAS antibody (ABIN969518) Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
Molecular Weight 37.7 kDa
Gene ID 355
HGNC 355
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling ProductDetails: References for anti-FAS antibody (ABIN969518) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details ProductDetails: References for anti-FAS antibody (ABIN969518) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

ProductDetails: References for anti-FAS antibody (ABIN969518)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Product cited in:

Liu, Jung, Orlandi, Yeh, Lin, Shiu, Wu, Chu, Lin, Chu: "The Fas-mediated apoptotic pathway in cardiac myxoma." in: International journal of surgical pathology, Vol. 18, Issue 6, pp. 493-8, 2010

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling ProductDetails: References for anti-FAS antibody (ABIN969518) back to top
Supplier Images
ELISA image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 2: Flow cytometric analysis of Hela cells using FAS mouse mAb (green) and nega...
Immunocytochemistry (ICC) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 3: Immunofluorescence analysis of Hela cells using FAS mouse mAb (green) . Blu...
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 4: Western blot analysis using FAS mouse mAb against Hela (1), Jurkat (2) cell...
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 5: Western blot analysis using FAS mAb against human FAS (AA: 87-278) recombin...