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anti-Human FAS antibody for Immunohistochemistry (Frozen Sections)

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • A630082H08Rik
  • AI196731
  • ALPS1A
  • APO-1
  • APO1
  • APT1
  • CD95
  • FAS
  • FAS1
  • FASTM
  • lpr
  • TNFR6
  • Tnfrsf6
  • TNFRSF6
Reactivity
Human
651
101
81
11
7
5
4
3
3
3
2
2
1
1
Host
Mouse
426
293
17
6
4
3
3
Clonality
Monoclonal
Conjugate
This FAS antibody is un-conjugated
74
64
51
33
16
8
7
6
4
4
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
340
295
213
130
104
77
60
54
49
44
23
19
12
9
7
5
4
4
3
3
3
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN1106610
$ 456.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088051456 ABIN1106620 IHC (fro) FACS Mouse IgG2a Log in to see B-G27 3
0.00088051456 ABIN1383736 IHC (fro) FACS Mouse IgG2a Log in to see B-G27 3
0.00088051456 ABIN1106614 Func IHC (fro) FACS Mouse IgG2a Log in to see B-G27
0.00088051456 ABIN371578 Func FACS IHC (fro) IP Mouse IgG1 Log in to see DX2 1
0.00088051456 ABIN187300 EIA Func IHC (fro) IP WB Mouse IgG1 Log in to see 5F-9
0.00088051456 ABIN371584 Func FACS IHC (fro) IP Mouse IgG2a Log in to see DX3 1
0.00088051456 ABIN228066 IHC (fro) IHC (p) Mouse IgG1 C-Term Log in to see
0.00088051456 ABIN440434 ELISA FACS IHC IHC (fro) IHC (p) IP Biotin Mouse IgG1 Log in to see DX2
0.00088051456 ABIN1383735 IHC (fro) FACS Mouse IgG2a Log in to see B-G27
0.00088051456 ABIN187262 Func FACS IHC (fro) IF Mouse IgM Log in to see IPO-4
0.00088051456 ABIN440429 FACS ICC IHC IHC (fro) IHC (p) IP FITC Mouse IgG1 Log in to see DX2
0.00088051456 ABIN440430 ELISA FACS ICC IHC IHC (fro) IHC (p) IP Biotin Mouse IgG1 Log in to see DX2
0.00088051456 ABIN440431 FACS IHC (fro) IP IHC PE Mouse IgG1 Log in to see DX2
0.00088051456 ABIN440435 FACS IHC (fro) IP IHC PE Mouse IgG1 Log in to see DX2
0.00088051456 ABIN440433 FACS IHC IHC (fro) IHC (p) IP FITC Mouse IgG1 Log in to see DX2
0.00088051456 ABIN266746 IHC (fro) IHC (p) IHC Rabbit IgG C-Term Log in to see Polyclonal
0.00088051456 ABIN187285 Func FACS IHC (fro) Mouse IgG1 Log in to see APO-1-1
0.00088051456 ABIN211593 FACS IHC (fro) IHC (p) IP Mouse IgG1 Extracellular Domain Log in to see
0.00088051456 ABIN1078008 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 26-173 Log in to see Polyclonal
0.00088051456 ABIN1858799 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 22-172 Log in to see Polyclonal

Top referenced anti-FAS antibody for Immunohistochemistry (Frozen Sections)

Similar anti-FAS Antibodies

Application / Reactivity Human
Activation (Act) 3 Antibodies
Apoptosis Blocking (AB) 3 Antibodies
Apoptosis Induction (AI) 2 Antibodies
Biochemical Assay (BCA) 1 Antibodies
Blocking Antibody (Inhibition) 5 Antibodies
Blocking Reagent (BR) 1 Antibodies
Dot Blot (DB) 19 Antibodies
ELISA 186 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 12 Antibodies
Flow Cytometry (FACS) 328 Antibodies
Fluorescence Microscopy (FM) 1 Antibodies
Functional Studies (Func) 50 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 16 Antibodies
Immunofluorescence (IF) 49 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 128 Antibodies

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Reactivity Human
(651), (101), (81), (11), (7), (5), (4), (3), (3), (3), (2), (2), (1), (1)
Host Mouse
(426), (293), (17), (6), (4), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FAS antibody is un-conjugated
(74), (64), (51), (33), (16), (8), (7), (6), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(340), (295), (213), (130), (104), (77), (60), (54), (49), (44), (23), (19), (12), (9), (7), (5), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 16 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS Antibody (ABIN1106610) Images
Specificity This antibody recognizes the human Fas antigen specifically.
No Cross-Reactivity Mouse (Murine)
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ammonium sulfate precipitation and affinity chromatography on protein A agarose
Immunogen Recombinant human Fas
Clone UB2
Isotype IgG1

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS Antibody (ABIN1106610) Images back to top
Antigen
Alternative Name CD95 / FAS (FAS Antibody Abstract)
Background It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas antigen is a cell-surface protein that mediates apoptosis. It is expressed in various tissues including the thymus and has structural homology with a number of cell-surface receptors, including tumor necrosis factor receptor and nerve growth factor receptor.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6
Gene ID 355
NCBI Accession NP_000034
UniProt P25445
Pathways p53 Signaling, Apoptosis, TCR Signaling

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS Antibody (ABIN1106610) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS Antibody (ABIN1106610) Images back to top
Reconstitution Prepare a stock solution by dissolving the lyophilized antibody in 100 μL of distilled water.
Buffer PBS ( pH 7.2), 0.09 % NaN3, 1 % sucrose
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

References for anti-FAS Antibody (ABIN1106610)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Background publications

Vega, Jazirehi, Huerta-Yepez, Bonavida: "Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non-Hodgkin's lymphoma cell line via inhibition of NF-kappa B activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 4, pp. 2174-83, 2005

Mezosi, Wang, Utsugi, Bajnok, Bretz, Gauger, Thompson, Baker: "Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 3, pp. 804-11, 2005

Hauptschein, Sloan, Torella, Moezzifard, Giel-Moloney, Zehetmeier, Unger, Ilag, Jay: "Functional proteomic screen identifies a modulating role for CD44 in death receptor-mediated apoptosis." in: Cancer research, Vol. 65, Issue 5, pp. 1887-96, 2005

Suhara, Fukuo, Yasuda, Tsubakimoto, Takemura, Kawamoto, Yokoi, Mogi, Kaimoto, Ogihara: "Homocysteine enhances endothelial apoptosis via upregulation of Fas-mediated pathways." in: Hypertension, Vol. 43, Issue 6, pp. 1208-13, 2004

Suhara, Kim, Kirshenbaum, Walsh: "Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation." in: Molecular and cellular biology, Vol. 22, Issue 2, pp. 680-91, 2001

Shinohara, Yagita, Ikawa, Oyaizu: "Fas drives cell cycle progression in glioma cells via extracellular signal-regulated kinase activation." in: Cancer research, Vol. 60, Issue 6, pp. 1766-72, 2000

Sata, Suhara, Walsh: "Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 2, pp. 309-16, 2000

Hiromatsu, Hoshino, Yagita, Koga, Sakisaka, Honda, Yang, Kayagaki, Okumura, Nonaka: "Functional Fas ligand expression in thyrocytes from patients with Graves' disease." in: The Journal of clinical endocrinology and metabolism, Vol. 84, Issue 8, pp. 2896-902, 1999

Kuwano, Miyazaki, Hagimoto, Kawasaki, Fujita, Kunitake, Kaneko, Hara: "The involvement of Fas-Fas ligand pathway in fibrosing lung diseases." in: American journal of respiratory cell and molecular biology, Vol. 20, Issue 1, pp. 53-60, 1999

Dai, Price, Brunner, Krantz: "Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon gamma to produce erythroid cell apoptosis." in: Blood, Vol. 91, Issue 4, pp. 1235-42, 1998

Ando, Hiroishi, Kaneko, Moriyama, Muto, Kayagaki, Yagita, Okumura, Imawari: "Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 11, pp. 5283-91, 1997

Boirivant, Pica, DeMaria, Testi, Pallone, Strober: "Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis." in: The Journal of clinical investigation, Vol. 98, Issue 11, pp. 2616-22, 1997

Watanabe-Fukunaga, Brannan, Copeland, Jenkins, Nagata: "Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis." in: Nature, Vol. 356, Issue 6367, pp. 314-7, 1992

Kobayashi, Hamamoto, Yamamoto, Ishii, Yonehara, Yonehara: "Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 24, pp. 9620-4, 1991

Yonehara, Ishii, Yonehara: "A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor." in: The Journal of experimental medicine, Vol. 169, Issue 5, pp. 1747-56, 1989

Product cited in:

Hata, Matsuzaki, Takeya, Yoshida, Sonoki, Nagasaki, Kuribayashi, Kawano, Takatsuki: "Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders." in: Blood, Vol. 86, Issue 5, pp. 1939-45, 1995

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling References for anti-FAS Antibody (ABIN1106610) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-FAS antibody (Fas (TNF Receptor Superfamily, Member 6)) (ABIN1106610) anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody