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anti-Mouse (Murine) FAS antibody for ELISA

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • AI196731
  • APO1
  • APT1
  • CD95
  • TNFR6
  • Tnfrsf6
  • lpr
  • TNFRSF6
  • ALPS1A
  • APO-1
  • FAS1
  • FASTM
  • A630082H08Rik
  • FAS
  • Fas (TNF receptor superfamily member 6)
  • Fas (TNF receptor superfamily, member 6)
  • Fas cell surface death receptor
  • fatty acid synthase
  • Fas
  • FAS
  • Fasn
Epitope
AA 1-169
48
33
28
23
16
13
13
13
11
10
10
9
8
7
7
6
6
5
5
5
5
4
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
660
96
85
13
9
6
4
3
3
3
2
2
1
1
1
Host
Rabbit
423
295
18
5
4
3
3
Clonality
Polyclonal
Conjugate
This FAS antibody is un-conjugated
77
64
52
31
16
8
6
6
4
4
4
4
4
4
4
3
2
2
2
1
1
1
1
1
Application
ELISA
331
300
216
141
110
88
67
56
45
44
26
19
12
8
7
5
4
4
3
3
3
2
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN2000161
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2000159 ELISA Rabbit IgG AA 1-169 Log in to see Polyclonal 1
1 ABIN1858797 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 188-319 Log in to see Polyclonal
1 ABIN1078009 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 22-169 Log in to see Polyclonal
1 ABIN1734281 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal
1 ABIN1586046 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN2618784 ELISA Biotin Rabbit IgG AA 22-169 Log in to see Polyclonal
1 ABIN2618788 ELISA WB Biotin Rabbit IgG AA 188-319 Log in to see Polyclonal
1 ABIN2427601 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2264774 IC IHC ELISA WB Rabbit IgG AA 22-169 Log in to see Polyclonal
1 ABIN2618779 ELISA Rabbit IgG AA 22-169 Log in to see Polyclonal
1 ABIN2618782 ELISA Rabbit IgG AA 188-319 Log in to see Polyclonal
1 ABIN1172024 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN4368596 ELISA WB Rabbit Log in to see Polyclonal
1 ABIN2649457 ELISA Rabbit Log in to see

Similar anti-FAS Antibodies

Application / Reactivity Mouse (Murine)
Cytotoxicity Test (CyTox) 2 Antibodies
ELISA 15 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 17 Antibodies
Functional Studies (Func) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 19 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 10 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies
Immunoprecipitation (IP) 9 Antibodies
Western Blotting (WB) 52 Antibodies

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope AA 1-169
(48), (33), (28), (23), (16), (13), (13), (13), (11), (10), (10), (9), (8), (7), (7), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(660), (96), (85), (13), (9), (6), (4), (3), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(423), (295), (18), (5), (4), (3), (3)
Clonality
Polyclonal
Conjugate This FAS antibody is un-conjugated
(77), (64), (52), (31), (16), (8), (6), (6), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Application ELISA
(331), (300), (216), (141), (110), (88), (67), (56), (45), (44), (26), (19), (12), (8), (7), (5), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS Antibody (ABIN2000161) Images
Specificity Mouse FAS / CD95
Sensitivity 0.00245 ng/well
Characteristics Produced in rabbits immunized with purified, recombinant Mouse CD95 (rM CD95, NP_032013.2, Met 1-Arg 169). CD95 specific IgG was purified by mouse CD95 affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS Antibody (ABIN2000161) Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized by the presence of an 80 amino acid death domain in its cytoplasmic tail. This domain is essential for the recruitment of a number of signaling components upon activation by either agonistic anti-CD95 antibodies or cognate CD95 ligand that initiate apoptosis. The complex of proteins that forms upon triggering of CD95 is called the death-inducting signaling complex (DISC). The DISC consists of an adaptor protein and initiator caspases and is essential for induction of apoptosis. CD95 is also crucial for the negative selection of B cells within the germinal center (GC). Impairment of CD95-mediated apoptosis results in defective affinity maturation and the persistence of autoreactive B-cell clones. Changes in the expression of CD95 and/or its ligand CD95L are frequently found in human cancer. The downregulation or mutation of CD95 has been proposed as a mechanism by which cancer cells avoid destruction by the immune system through reduced apoptosis sensitivity. Thus, CD95 has therefore been viewed as a tumor suppressor. CD95 has been reported to be involved in the activation of NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and the alternate pathways for CTL-mediated cytotoxicity. Accordingly, this protein is implicated in the pathogenesis of various malignancies and diseases of the immune system. The CD95/CD95L system was implicated in the etiology of inflammatory bowel disease (IBD) based, primarily, on the finding that CD95 is highly expressed in the intestinal epithelial cells and that epithelial apoptosis is increased in IBD.
NCBI Accession NP_032013.2
Pathways p53 Signaling, Apoptosis, TCR Signaling

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS Antibody (ABIN2000161) Images back to top
Application Notes ELISA ELISA: 0.1-0.2 μg/mL This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse FAS. The detection limit for Mouse FAS is 0.00245 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS Antibody (ABIN2000161) Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

References for anti-FAS Antibody (ABIN2000161)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Background publications

Peter, Legembre, Barnhart: "Does CD95 have tumor promoting activities?" in: Biochimica et biophysica acta, Vol. 1755, Issue 1, pp. 25-36, 2005