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anti-Mouse (Murine) FAS antibody for ELISA

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • A630082H08Rik
  • AI196731
  • ALPS1A
  • APO-1
  • APO1
  • APT1
  • CD95
  • FAS
  • FAS1
  • FASTM
  • lpr
  • TNFR6
  • Tnfrsf6
  • TNFRSF6
Epitope
AA 1-169
47
33
28
23
15
13
13
13
11
10
10
9
8
7
7
6
6
5
5
5
5
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
652
100
81
11
7
5
4
3
3
3
2
2
1
1
Host
Rabbit
427
292
17
6
4
3
3
Clonality
Polyclonal
Conjugate
This FAS antibody is un-conjugated
74
64
51
33
16
8
7
6
4
4
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Minimum Detection Limit
0.0049 ng/well
Application
ELISA
340
295
212
130
104
78
61
55
49
44
23
19
12
9
7
5
4
4
3
3
3
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN2000159
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0012187671 ABIN2000161 ELISA Rabbit IgG AA 1-169 Log in to see Polyclonal 1
0.0012187671 ABIN1858797 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 188-319 Log in to see Polyclonal
0.0012187671 ABIN1078009 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 22-169 Log in to see Polyclonal
0.0012187671 ABIN1586046 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.0012187671 ABIN2618784 ELISA Biotin Rabbit IgG AA 22-169 Log in to see Polyclonal
0.0012187671 ABIN2618788 ELISA WB Biotin Rabbit IgG AA 188-319 Log in to see Polyclonal
0.0012187671 ABIN1734281 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal
0.0012187671 ABIN2618779 ELISA Rabbit IgG AA 22-169 Log in to see Polyclonal
0.0012187671 ABIN2618782 ELISA Rabbit IgG AA 188-319 Log in to see Polyclonal
0.0012187671 ABIN2427601 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0012187671 ABIN2264774 IC IHC ELISA WB Rabbit IgG AA 22-169 Log in to see Polyclonal
0.0012187671 ABIN1172024 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.0012187671 ABIN1885025 ELISA WB Rabbit Log in to see Polyclonal
0.0012187671 ABIN2649457 ELISA Rabbit Log in to see

Similar anti-FAS Antibodies

Application / Reactivity Mouse (Murine)
Cytotoxicity Test (CyTox) 2 Antibodies
ELISA 15 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 24 Antibodies
Functional Studies (Func) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 17 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 20 Antibodies
Immunoprecipitation (IP) 9 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 50 Antibodies

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope AA 1-169
(47), (33), (28), (23), (15), (13), (13), (13), (11), (10), (10), (9), (8), (7), (7), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(652), (100), (81), (11), (7), (5), (4), (3), (3), (3), (2), (2), (1), (1)
Host Rabbit
(427), (292), (17), (6), (4), (3), (3)
Clonality
Polyclonal
Conjugate This FAS antibody is un-conjugated
(74), (64), (51), (33), (16), (8), (7), (6), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Minimum Detection Limit 0.0049 ng/well
Application ELISA
(340), (295), (212), (130), (104), (78), (61), (55), (49), (44), (23), (19), (12), (9), (7), (5), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS Antibody (ABIN2000159) Images
Specificity Mouse FAS / CD95
Characteristics Produced in rabbits immunized with purified, recombinant Mouse CD95 (rM CD95, NP_032013.2, Met 1-Arg 169). Total IgG was purified by Protein A affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS Antibody (ABIN2000159) Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized by the presence of an 80 amino acid death domain in its cytoplasmic tail. This domain is essential for the recruitment of a number of signaling components upon activation by either agonistic anti-CD95 antibodies or cognate CD95 ligand that initiate apoptosis. The complex of proteins that forms upon triggering of CD95 is called the death-inducting signaling complex (DISC). The DISC consists of an adaptor protein and initiator caspases and is essential for induction of apoptosis. CD95 is also crucial for the negative selection of B cells within the germinal center (GC). Impairment of CD95-mediated apoptosis results in defective affinity maturation and the persistence of autoreactive B-cell clones. Changes in the expression of CD95 and/or its ligand CD95L are frequently found in human cancer. The downregulation or mutation of CD95 has been proposed as a mechanism by which cancer cells avoid destruction by the immune system through reduced apoptosis sensitivity. Thus, CD95 has therefore been viewed as a tumor suppressor. CD95 has been reported to be involved in the activation of NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and the alternate pathways for CTL-mediated cytotoxicity. Accordingly, this protein is implicated in the pathogenesis of various malignancies and diseases of the immune system. The CD95/CD95L system was implicated in the etiology of inflammatory bowel disease (IBD) based, primarily, on the finding that CD95 is highly expressed in the intestinal epithelial cells and that epithelial apoptosis is increased in IBD.
NCBI Accession NP_032013.2
Pathways p53 Signaling, Apoptosis, TCR Signaling

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS Antibody (ABIN2000159) Images back to top
Application Notes ELISA ELISA: 0.5-1 µg/mL This antibody can be used at 0.5-1 µg/mL with the appropriate secondary reagents to detect Mouse FAS. The detection limit for Mouse FAS is 0.0049 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS Antibody (ABIN2000159) Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

References for anti-FAS Antibody (ABIN2000159)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Background publications

Peter, Legembre, Barnhart: "Does CD95 have tumor promoting activities?" in: Biochimica et biophysica acta, Vol. 1755, Issue 1, pp. 25-36, 2005