anti-Rat (Rattus) FAS antibody for Immunofluorescence

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • AI196731
  • APO1
  • APT1
  • CD95
  • TNFR6
  • Tnfrsf6
  • lpr
  • TNFRSF6
  • ALPS1A
  • APO-1
  • FAS1
  • FASTM
  • A630082H08Rik
  • FAS
  • Fas (TNF receptor superfamily member 6)
  • Fas (TNF receptor superfamily, member 6)
  • Fas cell surface death receptor
  • fatty acid synthase
  • Fas
  • FAS
  • Fasn
Epitope
N-Term
49
29
24
18
15
15
15
14
13
12
11
10
9
9
9
8
7
7
6
5
5
5
5
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
648
115
100
21
15
10
6
6
3
3
3
3
2
1
Host
Rabbit
422
304
29
5
4
3
3
Clonality
Polyclonal
Conjugate
This FAS antibody is un-conjugated
73
65
51
29
15
8
8
8
6
6
6
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
349
325
211
149
113
85
60
53
52
46
25
18
12
9
7
7
6
4
4
3
3
3
3
3
2
2
2
2
1
1
1
1
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Catalog No. ABIN1106611
$ 313.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN967816 IHC (f) IF IP WB Mouse IgG2a, kappa AA 1-163 Log in to see 13-Fas 5
1 ABIN967817 IHC (f) IF IP WB Mouse IgG2a, kappa AA 1-163 Log in to see 13-Fas 5
1 ABIN2506690 ICC IF IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN609579 ICC IHC (fro) IF IHC (p) IP WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2962723 ICC IHC (fro) IF IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1172026 ICC IF IHC WB FITC Rabbit IgG Log in to see Polyclonal
1 ABIN2618800 ICC IF IHC (fro) IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN2264772 IC IF IP IHC WB Rabbit IgG N-Term Log in to see Polyclonal

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope N-Term
(49), (29), (24), (18), (15), (15), (15), (14), (13), (12), (11), (10), (9), (9), (9), (8), (7), (7), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus)
(648), (115), (100), (21), (15), (10), (6), (6), (3), (3), (3), (3), (2), (1)
Host Rabbit
(422), (304), (29), (5), (4), (3), (3)
Clonality
Polyclonal
Conjugate This FAS antibody is un-conjugated
(73), (65), (51), (29), (15), (8), (8), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(349), (325), (211), (149), (113), (85), (60), (53), (52), (46), (25), (18), (12), (9), (7), (7), (6), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN1106611) Images
Specificity Recognizes FAS. No cross reactivity with other proteins.
Purification Immunoaffinity Chromatography
Immunogen A synthetic peptide corresponding to a sequence at the N-terminal of Rat FAS, different from the related Mouse sequence by seven amino acids.
Isotype IgG

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS antibody (ABIN1106611) Images back to top
Antigen
Alternative Name CD95 / FAS (FAS Antibody Abstract)
Background FAS (also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors, can induce apoptosis or, conversely, can deliver growth stimulatory signals. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor (TNF) receptors and the low-affinity nerve growth factor receptor (NGFR) and is mapped to 10q24.1. And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6
Gene ID 14102
NCBI Accession NP_032013
UniProt P25446
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS antibody (ABIN1106611) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS antibody (ABIN1106611) Images back to top
Reconstitution Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.
Concentration 0.5 mg/mL
Buffer 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide, 5 mg BSA
Preservative Sodium azide, Thimerosal (Merthiolate)
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-FAS antibody (ABIN1106611)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Background publications

Zhang, Miao, Sun, Tan, Qu, Xiong, Zhou, Lin: "Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer." in: Journal of medical genetics, Vol. 42, Issue 6, pp. 479-84, 2005

Desbarats, Birge, Mimouni-Rongy, Weinstein, Palerme, Newell: "Fas engagement induces neurite growth through ERK activation and p35 upregulation." in: Nature cell biology, Vol. 5, Issue 2, pp. 118-25, 2003

Arscott, Stokes, Myc, Giordano, Thompson, Baker: "Fas (CD95) expression is up-regulated on papillary thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 84, Issue 11, pp. 4246-52, 1999

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN1106611) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (N-Term) antibody (ABIN1106611) Immunocytochemical staining of HeLa Cells
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (N-Term) antibody (ABIN1106611) Paraffin Rat Spleen tissue lysate stained with CD95 / FAS
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (N-Term) antibody (ABIN1106611)

Lane 1: Recombinant Mouse FAS Protein 10ng.