anti-Rat (Rattus) FAS antibody for Western Blotting

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • AI196731
  • APO1
  • APT1
  • CD95
  • TNFR6
  • Tnfrsf6
  • lpr
  • TNFRSF6
  • ALPS1A
  • APO-1
  • FAS1
  • FASTM
  • A630082H08Rik
  • FAS
  • Fas (TNF receptor superfamily member 6)
  • Fas (TNF receptor superfamily, member 6)
  • Fas cell surface death receptor
  • fatty acid synthase
  • Fas
  • FAS
  • Fasn
Epitope
AA 87-109, N-Term
49
29
24
18
15
15
15
14
12
11
10
9
9
9
8
7
7
6
5
5
5
5
5
4
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
648
113
99
15
11
10
6
6
3
3
3
3
2
1
Host
Rabbit
415
303
24
5
4
3
3
Clonality
Polyclonal
Conjugate
This FAS antibody is un-conjugated
73
63
51
29
15
8
7
7
5
5
5
4
4
4
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
335
318
210
147
113
85
60
54
52
46
23
18
12
7
7
6
5
5
4
4
3
3
3
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN3044338
$ 200.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.9066148 ABIN967816 IHC (f) IF IP WB Mouse IgG2a, kappa AA 1-163 Log in to see 13-Fas 5
2.9066148 ABIN967817 IHC (f) IF IP WB Mouse IgG2a, kappa AA 1-163 Log in to see 13-Fas 5
2.9066148 ABIN3042386 WB Rabbit IgG AA 22-324 Log in to see Polyclonal 13
2.9066148 ABIN1106611 IHC (fro) IF IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 3
2.9066148 ABIN266061 IHC (p) IHC WB Rabbit Log in to see Polyclonal 3
2.9066148 ABIN1387305 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
2.9066148 ABIN1858796 ICC IHC IP WB Rabbit IgG AA 21-170 Log in to see Polyclonal
2.9066148 ABIN2704623 IHC WB Rabbit C-Term Log in to see Polyclonal
2.9066148 ABIN411481 IHC WB Rabbit IgG Log in to see Polyclonal
2.9066148 ABIN407955 IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
2.9066148 ABIN2467815 WB Chicken AA 21-165 Log in to see Polyclonal
2.9066148 ABIN3020739 WB Rabbit IgG Log in to see Polyclonal
2.9066148 ABIN2403472 IHC WB Rabbit IgG Log in to see Polyclonal
2.9066148 ABIN2427601 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
2.9066148 ABIN3030901 IHC (fro) IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
2.9066148 ABIN3030903 WB Rabbit IgG AA 22-324 Log in to see Polyclonal
1 ABIN726395 IF (p) IHC (p) WB Rabbit IgG AA 20-70 Log in to see Polyclonal 1
1 ABIN4899642 CyTOF FACS IHC WB Goat IgG AA 22-170 Log in to see Polyclonal 1
1 ABIN448412 IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal 3
1 ABIN126995 WB Rabbit Log in to see Polyclonal

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope AA 87-109, N-Term
(49), (29), (24), (18), (15), (15), (15), (14), (12), (11), (10), (9), (9), (9), (8), (7), (7), (6), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus)
(648), (113), (99), (15), (11), (10), (6), (6), (3), (3), (3), (3), (2), (1)
Host Rabbit
(415), (303), (24), (5), (4), (3), (3)
Clonality
Polyclonal
Conjugate This FAS antibody is un-conjugated
(73), (63), (51), (29), (15), (8), (7), (7), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(335), (318), (210), (147), (113), (85), (60), (54), (52), (46), (23), (18), (12), (7), (7), (6), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 14 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN3044338) Images
Purpose Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 6(FAS) detection. Tested with WB, IHC-P, IHC-F in Mouse,Rat.
Sequence YTDRKHYSDK CRRCAFCDEG HGL
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 6(FAS) detection. Tested with WB, IHC-P, IHC-F in Mouse,Rat.
Gene Name: Fas(TNF receptor superfamily, member 6)
Protein Name: Tumor necrosis factor receptor superfamily member 6
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of rat Fas(87-109aa, YTDRKHYSDKCRRCAFCDEGHGL).
Isotype IgG

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS antibody (ABIN3044338) Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background FAS(also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors, can induce apoptosis or, conversely, can deliver growth stimulatory signals. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor(TNF) receptors and the low-affinity nerve growth factor receptor(NGFR) and is mapped to 10q24.1. And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.

Synonyms: ALPS 1A antibody|ALPS1A antibody|APO 1 antibody|Apo 1 antigen antibody|APO 1 cell surface antigen antibody|Apo-1 antigen antibody|APO1 antibody|Apo1 antigen antibody|APO1 cell surface antigen antibody|Apoptosis antigen 1 antibody|Apoptosis mediating surface antigen FAS antibody|Apoptosis-mediating surface antigen FAS antibody|APT 1 antibody|APT1 antibody|CD 95 antibody|CD 95 antigen antibody|CD95 antibody|CD95 antigen antibody|Delta Fas antibody|Delta Fas/APO 1/CD95 antibody|Delta Fas/APO1/CD95 antibody|Fas(TNF receptor superfamily, member 6) antibody|FAS 1 antibody|FAS 827dupA antibody|Fas AMA antibody|FAS antibody|FAS Antigen antibody|Fas cell surface death receptor antibody|FAS1 antibody|FASLG receptor antibody|FASTM antibody|sFAS antibody|Surface antigen APO1 antibody|TNF receptor superfamily, member 6 antibody|TNFRSF 6 antibody|TNFRSF6 antibody|TNR6_HUMAN antibody|Tumor necrosis factor receptor superfamily member 6 antibody
UniProt Q63199
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS antibody (ABIN3044338) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat , Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS antibody (ABIN3044338) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-FAS antibody (ABIN3044338)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Product cited in:

Yeung, Wang, Yao, Liang, Tenny Chung, Chuai, Lee, Yang: "BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse." in: Cell death & disease, Vol. 8, Issue 3, pp. e2697, 2017

Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: "A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes." in: Natural products and bioprospecting, Vol. 5, Issue 3, pp. 159-66, 2015

Kan, Zhou, Jin, Yang: "Effects of PDTC on NF-?B expression and apoptosis in rats with severe acute pancreatitis-associated lung injury." in: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 3258-70, 2015

Liu, Su, Zhang, Zhang, Wang, Qian: "Rhodiola rosea suppresses thymus T-lymphocyte apoptosis by downregulating tumor necrosis factor-?-induced protein 8-like-2 in septic rats." in: International journal of molecular medicine, Vol. 36, Issue 2, pp. 386-98, 2015

Jiang, Li, Zhou, Wang, Zhang, Wang: "Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways." in: International journal of molecular medicine, Vol. 33, Issue 5, pp. 1298-304, 2014

Wu, Hu, Liu, Cao, Xu, Li, Li: "Nature and mechanisms of hepatocyte apoptosis induced by D-galactosamine/lipopolysaccharide challenge in mice." in: International journal of molecular medicine, Vol. 33, Issue 6, pp. 1498-506, 2014

Weng, Xie, Yi, Huang, Luo, Du, Chen, Liu, Chen, Chen: "Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 22, Issue 8, pp. 1197-205, 2014

Liu, Shan, Dong, Liu, Ma, Liu: "Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury." in: World journal of gastroenterology, Vol. 19, Issue 4, pp. 492-502, 2013

Li, Xu, Chu, Gao, Wang, Nie, Yang, Lv: "Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-/-) mice." in: Immunology letters, Vol. 156, Issue 1-2, pp. 68-81, 2013

Ma, Zhang, Zhang, Yang, Meng, Zhang, Zhou: "The effect of esculentoside A on lupus nephritis-prone BXSB mice." in: Archives of medical science : AMS, Vol. 9, Issue 2, pp. 354-60, 2013

Liu, Liu, Li, Wang, Zhao: "Hydrogen sulfide donor regulates alveolar epithelial cell apoptosis in rats with acute lung injury." in: Chinese medical journal, Vol. 126, Issue 3, pp. 494-9, 2013

Li, Xia, Wang, Li, Xue, Wu, Ye: "Relationship between aberrant methylation of FAS promoter and biological behavior of bladder urothelial carcinoma." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 31, Issue 6, pp. 794-8, 2011

Li, Peng, Li, Liu, Liang, Zhang: "Clinical significance of Fas and FasL protein expression in gastric carcinoma and local lymph node tissues." in: World journal of gastroenterology, Vol. 16, Issue 10, pp. 1274-8, 2010

Li, Chu, Gao, Li: "Apoptotic mechanism of MCF-7 breast cells in vivo and in vitro induced by photodynamic therapy with C-phycocyanin." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 1, pp. 80-9, 2009

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN3044338) back to top
Supplier Images
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (AA 87-109), (N-Term) antibody (ABIN3044338) Anti-CD95 antibody, Western blotting Lane 1: Recombinant Mouse FAS Protein 10ng Lane ...
Immunohistochemistry (IHC) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (AA 87-109), (N-Term) antibody (ABIN3044338) Anti-CD95 antibody, IHC(P) IHC(P): Rat Spleen Tissue Lysate