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Browse our HMGB1 Proteins (HMGB1)

Full name:
High-Mobility Group Box 1 Proteins (HMGB1)
On www.antibodies-online.com are 60 High-Mobility Group Box 1 (HMGB1) Proteins from 18 different suppliers available. Additionally we are shipping HMGB1 Antibodies (451) and HMGB1 Kits (68) and many more products for this protein. A total of 602 HMGB1 products are currently listed.
Synonyms:
Ac2-008, amphoterin, DEF, HMG-1, Hmg1, HMG3, Hmgb1, ik:tdsubc_1a5, p30, SBP-1, wu:fb23c02, xx:tdsubc_1a5, zgc:56110, zgc:77104
list all proteins Gene Name GeneID UniProt
HMGB1 3146 P09429
HMGB1 15289 P63158
HMGB1 25459 P63159

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HMGB1 Proteins (HMGB1) by Origin

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Top referenced HMGB1 Proteins

  1. Human HMGB1 Protein expressed in HEK-293 - ABIN2666551 : Min, Ko, Wu, Kim, Kwon, Kwak, Choi, Lee, Shin: Chaperone-like activity of high-mobility group box 1 protein and its role in reducing the formation of polyglutamine aggregates. in Journal of immunology (Baltimore, Md. : 1950) 2013 (PubMed)
    Show all 6 references for ABIN2666551

  2. Human HMGB1 Protein expressed in Human Cells - ABIN2002577 : Wen, Huang, Johnson, Reeck: A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1. in Nucleic acids research 1989 (PubMed)
    Show all 6 references for ABIN2002577

  3. Human HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN2002576 : Ge, Roeder: The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. in The Journal of biological chemistry 1994 (PubMed)
    Show all 5 references for ABIN2002576

  4. Mouse (Murine) HMGB1 Protein expressed in Human Cells - ABIN3216407 : Andersson, Erlandsson-Harris, Yang, Tracey: HMGB1 as a DNA-binding cytokine. in Journal of leukocyte biology 2002 (PubMed)
    Show all 5 references for ABIN3216407

  5. Mouse (Murine) HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN1079871 : Ruzzenente, Iacono, Conci, Bertuzzo, Salvagno, Ruzzenente, Campagnaro, Valdegamberi, Pachera, Bagante, Guglielmi: A novel serum marker for biliary tract cancer: diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC). in Surgery 2014 (PubMed)
    Show all 2 references for ABIN1079871

  6. Human HMGB1 Protein expressed in HEK-293 Cells - ABIN2181224 : Wang, Bloom, Zhang, Vishnubhakat, Ombrellino, Che, Frazier, Yang, Ivanova, Borovikova, Manogue, Faist, Abraham, Andersson, Andersson, Molina, Abumrad, Sama, Tracey: HMG-1 as a late mediator of endotoxin lethality in mice. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 2 references for ABIN2181224

  7. Human HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN1176814 : Maroso, Balosso, Ravizza, Liu, Aronica, Iyer, Rossetti, Molteni, Casalgrandi, Manfredi, Bianchi, Vezzani: Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures. in Nature medicine 2010 (PubMed)

  8. Human HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN1176823 : Scaffidi, Misteli, Bianchi: Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. in Nature 2002 (PubMed)

More Proteins for HMGB1 Interaction Partners

Human High-Mobility Group Box 1 (HMGB1) interaction partners

  1. LncRNA TUG1 knockdown enhances radiosensitivity of bladder cancer by suppressing HMGB1 expression.

  2. 2-O, 3-O desulfated heparin inhibited HMGB1 release, at least in part, by direct molecular inhibition of p300 HAT (show EP300 Proteins) activity.

  3. TLR4 (show TLR4 Proteins) signaling in HMGB1 mediated the suppressive function of Treg cells through the activation of the NF-kappaB (show NFKB1 Proteins) pathway.

  4. this study shows that patients with type 2 diabetes mellitus display elevated levels of HMGB1

  5. HMGB1-induced autophagy could maintain survival and function stability of peripheral regulatory T-cells from chronic hepatitis B patients

  6. The HMGB1 C-terminal tail serves as an intramolecular damper that modulates the interaction of the binding and bending B box with DNA.

  7. These results demonstrated that miR (show MLXIP Proteins)-142-3p regulates starvation-induced autophagy of Non-small-cell lung cancer cells by directly downregulating HMGB1 and subsequently activating the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) pathway.

  8. TREM-1 (show TREM1 Proteins), HMGB1 and RAGE (show AGER Proteins) in the Shoulder Tendon: Dual Mechanisms for Inflammation Based on the Coincidence of Glenohumeral Arthritis

  9. The results demonstrated reduction of cell viability upon increasing irinotecan concentration, up-regulated high-mobility group protein B1 gene expression, and down-regulated MMP9 (show MMP9 Proteins) mRNA.

  10. These findings demonstrate that the BRAF (show BRAF Proteins) V600E mutation down-regulates levels of HMGB1, likely through activation of the mitogen-activated protein kinase (show MAPK1 Proteins) (MAPK (show MAPK1 Proteins)) signaling pathways.

Pig (Porcine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. Systemic HMGB-1 levels were significantly elevated in both trauma groups when compared to the sham group. Haemorrhagic shock severity and duration were positively correlated with HMGB-1 levels and compared to baseline values, concentrations remained significantly increased in severe hemorrhage when compared to moderate hemorrhage.

  2. high levels of HMGB1 in the small intestine and its relation to high levels of HMGB1 in plasma of piglets infected with E. coli O55 that suffered from infection correlated with high levels of inflammatory cytokines and bacterial translocation; levels were higher than HMGB1 levels in piglets with mild clinical symptoms

  3. HMGB-1 may participate in the inflammatory response and liver injury in the late stage of acute liver failure

Cow (Bovine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. HMGB1 can act as an adjuvant in modulating the bovine immune system and thus lays a foundation for using HMGB1 as an adjuvant in various bovine vaccine preparations.

  2. Single-nucleotide polymorphism in the 3'-untranslated region of the HMGB1 gene affects the binding of target bta-miR (show MYLIP Proteins)-223 and is involved in mastitis.

  3. The mechanisms of interaction of the non-histone chromosomal protein (show HMGB2 Proteins) HMGB1 and linker histone H1 (show H1F0 Proteins) with DNA have been studied using circular dichroism and absorption spectroscopy.

  4. HMGB1 is able to induce considerable changes in DNA structure upon binding even when the amount of the protein directly associated with DNA is low

  5. Interaction between non-histone chromatin protein HMGB1 and linker histone H1 (show H1F0 Proteins)

  6. HMGB-1 might play a role in the pathological thickening of subchondral bone plate/osteophyte formation.

  7. Analysis of mechanical response generated by binding of DNA-bending protein HMGB1 to single tethered 48.5 kb lambda-DNA molecules finds that compaction of DNA increases with increasing HMGB1 concentration.

  8. Thrombomoduln not only binds to HMGB1 but also aids the proteolytic cleavage of HMGB1 by thrombin (show F2 Proteins).

Mouse (Murine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. 2-O, 3-O desulfated heparin inhibited HMGB1 release, at least in part, by direct molecular inhibition of p300 HAT (show EP300 Proteins) activity.

  2. this study reports a novel role of HMGB1 in controlling the maintenance and function of intestine-resident group-3 innate lymphoid cells that are important innate effector cells implicated in mucosal homeostasis and inflammatory bowel diseases pathogenesis

  3. this study shows that acute hypoxia upregulates high mobility group box-1 in a time-dependent manner

  4. Macrophage-produced HMGB1 leads to aortic inflammation and acts as a trigger for CD4 (show CD4 Proteins)(+) T-cell-produced IL-17 (show IL17A Proteins) during abdominal aortic aneurysm formation. HMGB1 release is dependent on Nox2 (show CYBB Proteins) activation, which can be inhibited by MSCs leading to attenuation of proinflammatory cytokines and protection against AAA (show AAAS Proteins) formation.

  5. Lipopolysaccharide treatment significantly suppressed the acute lung injury in mice with Acute lung injury/acute respiratory distress syndrome, accompanied with significant reduction in neutrophil influx, interleukin-17 (show IL17A Proteins), monocyte chemoattractant protein 1 (show CCL2 Proteins), high-mobility group box 1 protein, suppressor of cytokine signaling 3 (show SOCS3 Proteins), and surfactant protein D (SP-D (show SFTPD Proteins)) in the lungs .

  6. On lipopolysaccharide-induced tumor necrosis factor-alpha (show TNF Proteins) and HMGB1 expression in macrophages.

  7. these results identify PKCalpha and HMGB1 as important co-regulators involved in hydrogen peroxide-induced poly-ADP-ribose formation.

  8. metformin suppresses inflammation by inhibiting the extracellular activity of HMGB1.

  9. Platelet-derived HMGB1 mediated monocyte migration via the receptor for advanced glycation end products (RAGE (show AGER Proteins)) and suppressed apoptosis via toll-like receptor 4 (TLR4 (show TLR4 Proteins))-dependent activation of MAPK/ERK (show MAPK1 Proteins) (extracellular signal-regulated kinase) in monocytes. In conclusion, we identify platelet-derived HMGB1 as a critical regulator of monocyte recruitment and apoptosis, with potential implications in disease states associated

  10. Glycyrrhizin reduces HMGB1 and is protective against P. aeruginosa-induced keratitis with a clinical isolate that is noncytotoxic.

Horse (Equine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. High mobility group box-1 and nucleosomes might have use as biomarkers for horses with gastrointestinal disease.

  2. Extracellular HMGB-1 is widespread only in synovial membrane from diseased joints in horses with osteoarthritis.

  3. Osteochondral injury was associated with a significant increase in synovial HMGB-1 concentrations in horses with joint injuries, compared with results for clinically normal horses.

Rabbit High-Mobility Group Box 1 (HMGB1) interaction partners

  1. Airway pressure release ventilation reduces bronchoalveolar lavage fluid HMGB1 levels and lung water, preserving oxygenation and systemic blood pressure in experimental acute respiratory distress syndrome.

Zebrafish High-Mobility Group Box 1 (HMGB1) interaction partners

  1. HMGB1 is a critical factor for brain development, enabling survival and proliferation of neural progenitors that will form the forebrain structures.

HMGB1 Protein Profile

Protein Summary

a transcriptional regulator that may play a central role in the stabilization and/or assembly of several multifunctional complexes through protein-protein interactions

Alternative names and synonyms associated with HMGB1

  • high-mobility group box 1 (hmgb1)
  • high mobility group box 1 (hmgb1)
  • high mobility group box 1 (HMGB1)
  • high-mobility group box 1 (HMGB1)
  • high mobility group box 1 (Hmgb1)
  • high mobility group protein B1-like (LOC100392312)
  • high mobility group protein B1-like (LOC100754755)
  • high-mobility group box 1 (LOC100359149)
  • high-mobility group box 1a (hmgb1a)
  • HMG-box transcription factor 1 (Hbp1)
  • Ac2-008 protein
  • amphoterin protein
  • DEF protein
  • HMG-1 protein
  • Hmg1 protein
  • HMG3 protein
  • Hmgb1 protein
  • ik:tdsubc_1a5 protein
  • p30 protein
  • SBP-1 protein
  • wu:fb23c02 protein
  • xx:tdsubc_1a5 protein
  • zgc:56110 protein
  • zgc:77104 protein

Protein level used designations for HMGB1

high-mobility group box 1 , high mobility group protein 1 , sulfoglucuronyl carbohydrate binding protein , High mobility group protein B1 , HMG-1 , high mobility group protein B1 , Amphoterin , Sulfoglucuronyl carbohydrate binding protein , high-mobility group (nonhistone chromosomal) protein 1 , non-histone protein HMG1 , amphoterin , heparin-binding protein p30 , high mobility group 1 , high mobility group protein B1-like protein , high mobility group 1 protein , high mobility group protein HMG1 , high mobility group protein B1-like , High mobility group protein 1 , high mobility group box 1 , tdsubc_1a5 , HMG box transcription factor 1 , HMG box-containing protein 1 , HMG-box containing protein 1 , high mobility group box transcription factor 1

GENE ID SPECIES
100136339 Oncorhynchus mykiss
394834 Xenopus (Silurana) tropicalis
452518 Pan troglodytes
100137373 Papio anubis
100194543 Salmo salar
403170 Canis lupus familiaris
3146 Homo sapiens
445521 Sus scrofa
282691 Bos taurus
15289 Mus musculus
25459 Rattus norvegicus
100033873 Equus caballus
100328641 Oryctolagus cuniculus
395724 Gallus gallus
380530 Xenopus laevis
100392312 Callithrix jacchus
100754755 Cricetulus griseus
100359149 Oryctolagus cuniculus
321622 Danio rerio
27080 Rattus norvegicus
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