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Browse our HMGB1 Proteins (HMGB1)

Full name:
High-Mobility Group Box 1 Proteins (HMGB1)
On www.antibodies-online.com are 63 High-Mobility Group Box 1 (HMGB1) Proteins from 19 different suppliers available. Additionally we are shipping HMGB1 Antibodies (459) and HMGB1 Kits (62) and many more products for this protein. A total of 607 HMGB1 products are currently listed.
Synonyms:
Ac2-008, amphoterin, DEF, HMG-1, Hmg1, HMG3, Hmgb1, ik:tdsubc_1a5, p30, SBP-1, wu:fb23c02, xx:tdsubc_1a5, zgc:56110, zgc:77104
list all proteins Gene Name GeneID UniProt
HMGB1 3146 P09429
HMGB1 15289 P63158
HMGB1 25459 P63159

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HMGB1 Proteins (HMGB1) by Origin

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Top referenced HMGB1 Proteins

  1. Human HMGB1 Protein expressed in HEK-293 - ABIN2666551 : Min, Ko, Wu, Kim, Kwon, Kwak, Choi, Lee, Shin: Chaperone-like activity of high-mobility group box 1 protein and its role in reducing the formation of polyglutamine aggregates. in Journal of immunology (Baltimore, Md. : 1950) 2013 (PubMed)
    Show all 6 references for ABIN2666551

  2. Human HMGB1 Protein expressed in Human Cells - ABIN2002577 : Wen, Huang, Johnson, Reeck: A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1. in Nucleic acids research 1989 (PubMed)
    Show all 6 references for ABIN2002577

  3. Mouse (Murine) HMGB1 Protein expressed in Human Cells - ABIN3216407 : Ge, Roeder: The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. in The Journal of biological chemistry 1994 (PubMed)
    Show all 5 references for ABIN3216407

  4. Human HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN2002576 : Andersson, Erlandsson-Harris, Yang, Tracey: HMGB1 as a DNA-binding cytokine. in Journal of leukocyte biology 2002 (PubMed)
    Show all 5 references for ABIN2002576

  5. Human HMGB1 Protein expressed in HEK-293 Cells - ABIN2181224 : Wang, Bloom, Zhang, Vishnubhakat, Ombrellino, Che, Frazier, Yang, Ivanova, Borovikova, Manogue, Faist, Abraham, Andersson, Andersson, Molina, Abumrad, Sama, Tracey: HMG-1 as a late mediator of endotoxin lethality in mice. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 2 references for ABIN2181224

  6. Mouse (Murine) HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN1079871 : Ruzzenente, Iacono, Conci, Bertuzzo, Salvagno, Ruzzenente, Campagnaro, Valdegamberi, Pachera, Bagante, Guglielmi: A novel serum marker for biliary tract cancer: diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC). in Surgery 2014 (PubMed)
    Show all 2 references for ABIN1079871

  7. Human HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN1176814 : Maroso, Balosso, Ravizza, Liu, Aronica, Iyer, Rossetti, Molteni, Casalgrandi, Manfredi, Bianchi, Vezzani: Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures. in Nature medicine 2010 (PubMed)

  8. Human HMGB1 Protein expressed in Escherichia coli (E. coli) - ABIN1176823 : Scaffidi, Misteli, Bianchi: Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. in Nature 2002 (PubMed)

More Proteins for HMGB1 Interaction Partners

Human High-Mobility Group Box 1 (HMGB1) interaction partners

  1. the translocation of nuclear HMGB1 to the plasma membrane, and then its release in a microvesicle-associated form, is reported.

  2. HMGB1 is a ubiquitous redox-sensitive multifunctional protein.

  3. Studies indicate that interleukin (IL)-1beta (show IL1B Proteins), IL-1alpha, IL-33 (show IL33 Proteins) and high-mobility group box 1 (HMGB1) enter the extracellular space through mechanisms collectively known as unconventional secretion.

  4. Cytoplasmic HMGB1 expression is associated with tumor-infiltrating lymphocyte (TIL (show TLR1 Proteins)) levels in breast cancer.

  5. High HMGB1 expression is associated with invasion and metastasis of cervical cancer.

  6. High HMGB1 may promote atherosclerosis progression via modulating the imbalance in the Treg/Th17 ratio.

  7. The role of HMGB1 as a predictive biomarker of outcome in injured patients and hypothesizes.

  8. Authors confirmed that miR (show MLXIP Proteins)-200a could directly bind to TP73-AS1 and the 3'UTR of HMGB1; TP73-AS1 competed with HMGB1 for miR (show MLXIP Proteins)-200a binding.

  9. Findings suggest that high mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling pathway may contribute to the development and progression of gastric cancer via the nuclear factor kappa B pathway.

  10. Regnase-1 can be induced by HMGB1 in microglia and negatively regulates HMGB1-mediated neuroinflammation and neuronal toxicity

Pig (Porcine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. Systemic HMGB-1 levels were significantly elevated in both trauma groups when compared to the sham group. Haemorrhagic shock severity and duration were positively correlated with HMGB-1 levels and compared to baseline values, concentrations remained significantly increased in severe hemorrhage when compared to moderate hemorrhage.

  2. high levels of HMGB1 in the small intestine and its relation to high levels of HMGB1 in plasma of piglets infected with E. coli O55 that suffered from infection correlated with high levels of inflammatory cytokines and bacterial translocation; levels were higher than HMGB1 levels in piglets with mild clinical symptoms

  3. HMGB-1 may participate in the inflammatory response and liver injury in the late stage of acute liver failure

Cow (Bovine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. HMGB1 can act as an adjuvant in modulating the bovine immune system and thus lays a foundation for using HMGB1 as an adjuvant in various bovine vaccine preparations.

  2. Single-nucleotide polymorphism in the 3'-untranslated region of the HMGB1 gene affects the binding of target bta-miR (show MYLIP Proteins)-223 and is involved in mastitis.

  3. The mechanisms of interaction of the non-histone chromosomal protein (show HMGB2 Proteins) HMGB1 and linker histone H1 (show H1F0 Proteins) with DNA have been studied using circular dichroism and absorption spectroscopy.

  4. HMGB1 is able to induce considerable changes in DNA structure upon binding even when the amount of the protein directly associated with DNA is low

  5. Interaction between non-histone chromatin protein HMGB1 and linker histone H1 (show H1F0 Proteins)

  6. HMGB-1 might play a role in the pathological thickening of subchondral bone plate/osteophyte formation.

  7. Analysis of mechanical response generated by binding of DNA-bending protein HMGB1 to single tethered 48.5 kb lambda-DNA molecules finds that compaction of DNA increases with increasing HMGB1 concentration.

  8. Thrombomoduln not only binds to HMGB1 but also aids the proteolytic cleavage of HMGB1 by thrombin (show F2 Proteins).

Mouse (Murine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. The TLR4-HMGB1 signaling pathway affects the process of autoimmune myositis inflammation by regulating the expression of MHC-I and other pro-inflammatory cytokines

  2. HMGB1 plays an important role in cerebral ischemic stroke in diabetic mice.

  3. this study shows that IL-33 (show IL33 Proteins) is likely a major factor in acute respiratory distress syndrome, and the release of HMGB1 may be correlated with up-regulation of IL-33 (show IL33 Proteins) expression

  4. Data indicate that high mobility group box-1 (HMGB1)-toll-like receptor 4 (TLR4 (show TLR4 Proteins)) signalling pathway plays an important role in the activation of macrophages.

  5. HMGB1 promotes intraoral palatal wound healing through RAGE (show AGER Proteins)-dependent mechanisms.

  6. Inhibition of HMGB1 by miR (show MLXIP Proteins)-141 may block the process of autophagosome formation in acute pancreatitis through the HMGB1/Beclin-1 (show BECN1 Proteins) pathway.

  7. miR (show MLXIP Proteins)-142-3p inhibits hypoxia/reoxygenation-induced apoptosis and fibrosis of cardiomyocytes, partly at least, by the direct inhibition of HMGB1 expression.

  8. HMGB1 expression negatively correlated with miR2055b expression in lipopolysaccharide-induced sepsis.

  9. HMGB1 might play an important role in the acute inflammatory responses to C. difficile toxin A (TcdA), affect early inflammatory factors, and induce inflammation via the HMGB1-TLR4 (show TLR4 Proteins) pathway.

  10. These findings confirmed that CCl4based fibrosis induced hepatoprotection, and provided evidence that fibrosis inhibited the translocation and release of HMGB1, and the proinflammatory response triggered by HMGB1. This alleviated liver damage following exposure to DGalN/LPS (show TLR4 Proteins) challenge.

Horse (Equine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. High mobility group box-1 and nucleosomes might have use as biomarkers for horses with gastrointestinal disease.

  2. Extracellular HMGB-1 is widespread only in synovial membrane from diseased joints in horses with osteoarthritis.

  3. Osteochondral injury was associated with a significant increase in synovial HMGB-1 concentrations in horses with joint injuries, compared with results for clinically normal horses.

Rabbit High-Mobility Group Box 1 (HMGB1) interaction partners

  1. Airway pressure release ventilation reduces bronchoalveolar lavage fluid HMGB1 levels and lung water, preserving oxygenation and systemic blood pressure in experimental acute respiratory distress syndrome.

Zebrafish High-Mobility Group Box 1 (HMGB1) interaction partners

  1. HMGB1 is a critical factor for brain development, enabling survival and proliferation of neural progenitors that will form the forebrain structures.

HMGB1 Protein Profile

Protein Summary

a transcriptional regulator that may play a central role in the stabilization and/or assembly of several multifunctional complexes through protein-protein interactions

Alternative names and synonyms associated with HMGB1

  • high-mobility group box 1 (hmgb1)
  • high mobility group box 1 (hmgb1)
  • high mobility group box 1 (HMGB1)
  • high-mobility group box 1 (HMGB1)
  • high mobility group box 1 (Hmgb1)
  • high mobility group protein B1-like (LOC100392312)
  • high mobility group protein B1-like (LOC100754755)
  • high-mobility group box 1 (LOC100359149)
  • high-mobility group box 1a (hmgb1a)
  • HMG-box transcription factor 1 (Hbp1)
  • Ac2-008 protein
  • amphoterin protein
  • DEF protein
  • HMG-1 protein
  • Hmg1 protein
  • HMG3 protein
  • Hmgb1 protein
  • ik:tdsubc_1a5 protein
  • p30 protein
  • SBP-1 protein
  • wu:fb23c02 protein
  • xx:tdsubc_1a5 protein
  • zgc:56110 protein
  • zgc:77104 protein

Protein level used designations for HMGB1

high-mobility group box 1 , high mobility group protein 1 , sulfoglucuronyl carbohydrate binding protein , High mobility group protein B1 , HMG-1 , high mobility group protein B1 , Amphoterin , Sulfoglucuronyl carbohydrate binding protein , high-mobility group (nonhistone chromosomal) protein 1 , non-histone protein HMG1 , amphoterin , heparin-binding protein p30 , high mobility group 1 , high mobility group protein B1-like protein , high mobility group 1 protein , high mobility group protein HMG1 , high mobility group protein B1-like , High mobility group protein 1 , high mobility group box 1 , tdsubc_1a5 , HMG box transcription factor 1 , HMG box-containing protein 1 , HMG-box containing protein 1 , high mobility group box transcription factor 1

GENE ID SPECIES
100136339 Oncorhynchus mykiss
394834 Xenopus (Silurana) tropicalis
452518 Pan troglodytes
100137373 Papio anubis
100194543 Salmo salar
403170 Canis lupus familiaris
3146 Homo sapiens
445521 Sus scrofa
282691 Bos taurus
15289 Mus musculus
25459 Rattus norvegicus
100033873 Equus caballus
100328641 Oryctolagus cuniculus
395724 Gallus gallus
380530 Xenopus laevis
100392312 Callithrix jacchus
100754755 Cricetulus griseus
100359149 Oryctolagus cuniculus
321622 Danio rerio
27080 Rattus norvegicus
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