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anti-Mouse (Murine) HRAS antibody for Enzyme Immunoassay

Recommended HRAS Antibody (supplied by: Log in to see )

Antigen
V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Antibodies
  • AI929937
  • c-bas/has
  • C-BAS/HAS
  • C-H-RAS
  • c-H-ras
  • c-Ha-ras
  • C-HA-RAS1
  • c-rasHa
  • CTLO
  • H-RAS
  • H-Ras
  • H-ras
  • H-RASIDX
  • Ha-ras
  • HAMSV
  • Harvey-ras
  • HRAS
  • hras
  • Hras-1
  • HRAS1
  • hras1
  • K-ras
  • K-Ras
  • K-RAS
  • Ki-ras
  • Kras-2
  • Kras2
  • N-RAS
  • N-Ras
  • p21B
  • ras
  • rash1
  • RASH1
  • zgc:110250
Epitope
C-Term, AA 153-184
18
8
5
5
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
107
59
55
5
4
2
Host
Rabbit
94
30
2
1
Clonality
Polyclonal
Conjugate
This HRAS antibody is un-conjugated
7
6
6
2
2
2
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
90
42
27
22
18
17
5
5
2
2
2
1
1
1
Supplier
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Catalog No. ABIN952792
$ 390.50
Plus shipping costs $45.00

Top referenced anti-HRAS antibody for Enzyme Immunoassay

Similar anti-HRAS Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 19 Antibodies 27 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 3 Antibodies
Flow Cytometry (FACS) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 6 Antibodies
Immunofluorescence (IF) 9 Antibodies 29 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 10 Antibodies 20 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 36 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies

General

Antigen V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Antibodies
Epitope C-Term, AA 153-184
(18), (8), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(107), (59), (55), (5), (4), (2)
Host Rabbit
(94), (30), (2), (1)
Clonality
Polyclonal
Conjugate This HRAS antibody is un-conjugated
(7), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(90), (42), (27), (22), (18), (17), (5), (5), (2), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-HRAS Antibody

Target Details HRAS Application Details Handling References for anti-HRAS Antibody (ABIN952792) Images
Specificity This antibody recognizes Human and Mouse HRAS (C-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 153-184 amino acids from the C-terminal region of human HRAS
Isotype Ig

Target Details HRAS

Product Details anti-HRAS Antibody Application Details Handling References for anti-HRAS Antibody (ABIN952792) Images back to top
Antigen
Alternative Name HRAS (HRAS Antibody Abstract)
Background This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.Synonyms: GTPase HRas, H-Ras, H-Ras-1, HRAS1, Ha-Ras, c-H-ras, p21ras, v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Molecular Weight 21298 Da
Gene ID 3265
NCBI Accession NP_001123914
Pathways p53 Signaling, MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HRAS Antibody Target Details HRAS Handling References for anti-HRAS Antibody (ABIN952792) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-HRAS Antibody Target Details HRAS Application Details References for anti-HRAS Antibody (ABIN952792) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HRAS Antibody (ABIN952792)

Product Details anti-HRAS Antibody Target Details HRAS Application Details Handling Images back to top
Background publications

Ma, Liu, Wu, Terada: "p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior." in: Oncogene, Vol. 29, Issue 41, pp. 5559-67, 2010

van Engen-van Grunsven, van Dijk, Ruiter, Klaasen, Mooi, Blokx: "HRAS-mutated Spitz tumors: A subtype of Spitz tumors with distinct features." in: The American journal of surgical pathology, Vol. 34, Issue 10, pp. 1436-41, 2010

Li, Wang, Liu, Paulson, Yee, Zhang: "Transcriptional factor HBP1 targets P16(INK4A), upregulating its expression and consequently is involved in Ras-induced premature senescence." in: Oncogene, Vol. 29, Issue 36, pp. 5083-94, 2010

Kwack, Song, Pyun, Lee, Cho: "[Study on association between an H-RAS gene polymorphism and gastric cancer development]." in: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 56, Issue 2, pp. 78-82, 2010

Amosenko, Korchagina, Matveeva, Vaganov, Vlasov, Poltavets, Veselov, Garkavtseva, Poliakov: "[Mutation analysis of K-ras protooncogene in colorectal adenocarcinomas and polyps in Russian patients]." in: Genetika, Vol. 46, Issue 5, pp. 700-8, 2010

Images

Product Details anti-HRAS Antibody Target Details HRAS Application Details Handling References for anti-HRAS Antibody (ABIN952792) back to top
Supplier Images
Immunofluorescence (IF) image for anti-HRAS antibody (V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog) (C-Term) (ABIN952792) Confocal immunofluorescent analysis of HRAS Antibody (C-term) Cat.-No AP52096PU-N wit...
Western Blotting (WB) image for anti-HRAS antibody (V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog) (C-Term) (ABIN952792) Western blot analysis of HRAS (arrow) using HRAS Antibody (C-term) Cat.-No AP52096PU-...
Western Blotting (WB) image for anti-HRAS antibody (V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog) (C-Term) (ABIN952792) Western blot analysis of HRAS Antibody (C-term) in mouse cerebellum tissue lysates (3...