Ras, a signal transducer, was first characterized as the transforming genes of Harvey &Kristen sarcoma virus (1). The Ras family (H-Ras, N-Ras, and K-Ras) regulates cellgrowth, differentiation and apoptosis (2). Switching from an active or resting state, Rascan either bind GTP or GDP respectively. In the triphosphate conformation, Ras willinteract with GTPase activating protein (GAP) to increase its activity (3). Mutations inany of the three isoforms can convert these proteins into active oncogenes. Additionally,Ras mutations are found in 30 % of all human cancer (4). Alternate Names: anti-c H ras 1 antibody, anti-c H ras 1 protein antibody, anti-c H ras antibody, anti-chas/bas p21 protein antibody, anti-c ras Ki 2 protein antibody, anti-cHras antibody,anti-G1III6 N ras antibody, anti-GTPase HRas antibody, anti-H Ras 1 antibody, anti-Hras antibody, anti-H RasIDX antibody, anti-Ha ras antibody, anti-Harvey ras antibody,anti-Harvey rat sarcoma virus oncogene 1 antibody, anti-Hras 1 antibody, anti-HRASantibody, anti-Hras1 antibody, anti-K ras antibody, anti-N ras antibody, anti-N rasoncogene antibody, anti-P19 H RasIDX protein antibody, anti-p21 protein antibody,anti-p21ras antibody, anti-RASH 1 antibody, anti-RASH1 antibody, anti-Transformingprotein p21 antibody, anti-v Ha ras Harvey rat sarcoma viral oncogene homologantibody. Gene Symbol: HRAS
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.