Browse our NOXA Proteins (PMAIP1)

Full name:
Phorbol-12-Myristate-13-Acetate-Induced Protein 1 Proteins (PMAIP1)
On www.antibodies-online.com are 6 Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) Proteins from 4 different suppliers available. Additionally we are shipping NOXA Antibodies (130) and NOXA Kits (11) and many more products for this protein. A total of 162 NOXA products are currently listed.
Synonyms:
APR, Noxa, PMAIP1, TN3, zgc:162379
list all proteins Gene Name GeneID UniProt
PMAIP1 5366 Q13794
PMAIP1 58801 Q9JM54
PMAIP1 492821 Q5U777

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More Proteins for NOXA Interaction Partners

Zebrafish Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) interaction partners

  1. Therefore, the current findings indicate that Noxa is a novel regulator of early mitosis before 75% epiboly stage when it translates into a key mediator of apoptosis in subsequent embryogenesis.

Human Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) interaction partners

  1. Noxa is involved in X-ray-induced lung injury.

  2. Arsenic trioxide induces Noxa-dependent apoptosis in rhabdomyosarcoma cells and acts synergistically with antimicrotubule drugs.

  3. knockdown of MCL-1 (show MCL1 Proteins) in MRT cell lines induced apoptosis and increased DOX sensitivity in malignant rhabdoid tumor cells

  4. high levels of miR21 expression may induce gastric cancer migration and invasion via the downregulation of Noxa expression

  5. Inhibition of SIRT1 (show SIRT1 Proteins) could induce the Noxa expression in A549/DDP (show TIMM8A Proteins) cells.

  6. Fluorizoline bind to prohibitin (show PHB Proteins), inducing mitochondrial apoptotic pathway through NOXA and BIM (show BCL2L11 Proteins) upregulation.

  7. Noxa demethylation has a role in Bortezomib resistance in mantle cell lymphoma

  8. SATB1 (show SATB1 Proteins) as a Dual Regulator of Anti-Apoptotic BCL2 (show BCL2 Proteins) and Pro-Apoptotic NOXA Genes

  9. ALK-negative anaplastic large cell lymphoma is sensitive to bortezomib through Noxa upregulation and release of Bax (show BAX Proteins) from Bcl-2 (show BCL2 Proteins).

  10. BCL2 (show BCL2 Proteins) and BCLX (show BCL2L1 Proteins) phosphorylation represents a priming event in mitotic cell death that is triggered by NOXA-dependent MCL1 (show MCL1 Proteins) degradation. The MCL1 (show MCL1 Proteins) decay allows in turn BIM (show BCL2L11 Proteins)-dependent cell death.

Mouse (Murine) Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) interaction partners

  1. Noxa is involved in X-ray-induced lung injury.

  2. Fluorizoline bind to prohibitin (show PHB Proteins), inducing mitochondrial apoptotic pathway through NOXA and BIM (show BCL2L11 Proteins) upregulation.

  3. In addition, studies in leukemia Jurkat T cells support the existence of the Sall2 (show SALL2 Proteins)/Noxa axis, and the significance of this axis on the apoptotic response to doxorubicin in cancer cells.

  4. Our data demonstrate that ES cells are uniquely sensitive to CDK1 (show CDK1 Proteins) inhibition via a p53 (show TP53 Proteins)/NOXA/MCL1 (show MCL1 Proteins) pathway.

  5. Overall, these data reveal a Noxa-mediated signaling pathway that couples lysosomal membrane permeabilization with mitochondrial outer membrane permeabilization and ultimate apoptosis during oxidative stress.

  6. by preventing the consumption of IL-15 (show IL15 Proteins), Bim (show BCL2L11 Proteins) limits the role of Noxa and Puma (show BBC3 Proteins) in causing the death of effector cells with less memory potential.

  7. Induction of noxa does not influence ischemic neuronal injury.

  8. the current findings indicate that Noxa is a novel regulator of early mitosis before 75% epiboly stage when it translates into a key mediator of apoptosis in subsequent embryogenesis.

  9. Noxa controls expansion of erythroid precursors and RBC (show CACNA1C Proteins) production in vivo under conditions of induced anemia.

  10. Noxa is targeted to the mitochondrial membrane where it neutralises Mcl-1 (show MCL1 Proteins) via its C-terminal BH3-domain.

NOXA (PMAIP1) Protein Profile

Protein Summary

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Alternative names and synonyms associated with NOXA (PMAIP1)

  • phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)
  • phorbol-12-myristate-13-acetate-induced protein 1 (pmaip1)
  • phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1)
  • APR protein
  • Noxa protein
  • PMAIP1 protein
  • TN3 protein
  • zgc:162379 protein

Protein level used designations for PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1 , Noxa , PMA-induced protein 1 , adult T cell leukemia-derived PMA-responsive , immediate-early-response protein APR , protein Noxa

GENE ID SPECIES
397278 Sus scrofa
737247 Pan troglodytes
751765 Danio rerio
5366 Homo sapiens
58801 Mus musculus
492821 Rattus norvegicus
100502558 Canis lupus familiaris
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