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anti-Hamster p53 antibody for Immunohistochemistry

Recommended p53 Antibody (supplied by: Log in to see )

Antigen
Tumor Protein P53 (TP53) Antibodies
  • bbl
  • BCC7
  • bfy
  • bhy
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • LFS1
  • p44
  • P53
  • p53
  • tp53
  • TP53
  • Tp53
  • TpMs
  • Trp53
  • TRP53
  • wu:fb40d06
  • Xp53
  • zgc:111919
Epitope
AA 370-378, C-Term
140
87
63
54
51
50
49
48
47
46
43
40
39
30
27
25
22
20
19
17
17
13
13
13
13
13
12
12
9
9
9
8
8
8
8
8
8
8
7
7
7
6
6
6
6
6
6
6
6
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Hamster, Human, Monkey, Mouse (Murine), Rat (Rattus)
1783
319
268
99
34
21
19
13
11
10
10
10
8
5
4
4
4
3
3
3
2
2
1
Host
Mouse
1235
653
7
4
3
1
1
Clonality
Monoclonal
Conjugate
This p53 antibody is un-conjugated
61
51
39
33
23
23
17
17
14
14
14
14
14
14
13
6
4
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
1419
601
528
318
315
307
234
156
101
87
53
39
35
17
16
12
12
11
11
9
4
3
3
3
2
2
2
1
1
1
1
1
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Catalog No. ABIN3026354
$ 361.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011344873 ABIN3026355 FACS IF IHC Mouse IgG2b, kappa AA 370-378, C-Term Log in to see PAb 122
0.0011344873 ABIN201678 FACS IP IHC WB Mouse IgG2b AA 371-380 Log in to see

Similar anti-p53 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Hamster Monkey
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Transfected Cell Culture (TCC) 1 Antibodies
RNA Interference (RNAi) 1 Antibodies
Radioimmunoassay (RIA) 54 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Intracellular Staining (ICS) 3 Antibodies 1 Antibodies 1 Antibodies 1 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 290 Antibodies 44 Antibodies

General

Antigen Tumor Protein P53 (TP53) Antibodies
Epitope AA 370-378, C-Term
(140), (87), (63), (54), (51), (50), (49), (48), (47), (46), (43), (40), (39), (30), (27), (25), (22), (20), (19), (17), (17), (13), (13), (13), (13), (13), (12), (12), (9), (9), (9), (8), (8), (8), (8), (8), (8), (8), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Hamster, Human, Monkey, Mouse (Murine), Rat (Rattus)
(1783), (319), (268), (99), (34), (21), (19), (13), (11), (10), (10), (10), (8), (5), (4), (4), (4), (3), (3), (3), (2), (2), (1)
Host Mouse
(1235), (653), (7), (4), (3), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This p53 antibody is un-conjugated
(61), (51), (39), (33), (23), (23), (17), (17), (14), (14), (14), (14), (14), (14), (13), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
(1419), (601), (528), (318), (315), (307), (234), (156), (101), (87), (53), (39), (35), (17), (16), (12), (12), (11), (11), (9), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-p53 Antibody

Target Details p53 Application Details Handling Images
Characteristics This antibody is specific to a conserved determinant of the p53 protein. It has been used successfully to immunoprecipitate p53 oncoprotein complexes with simian virus 40 (SV40) large T antigen. Reportedly, the p53 antibody precipitated the most ATPase-active form of T antigen. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. When DNA damage occurs, it can activate repair proteins, arrest growth by holding the cell cycle at the G1/S regulation point, thereby increasing time available for repair, and if the damage is not repairable, initiate apoptosis.
Mutations involving p53 are found in a wide variety of malignant tumors including breast, ovary, bladder, colon, lung, and melanoma. The substitution of an arginine for a proline residue at position 72 may result in cancer susceptibility, but this has not be conclusively determined.
Purity Protein G affinity chromatography
Immunogen SV40-transformed mouse B4 cells were used as the immunogen for this antibody. Its epitope maps near the C-terminus end (aa 370-378) of p53.
Clone PAb 122
Isotype IgG2b, kappa

Target Details p53

Product Details anti-p53 Antibody Application Details Handling Images back to top
Antigen
Alternative Name p53 (TP53 Antibody Abstract)
Gene ID 7157
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling

Application Details

Product Details anti-p53 Antibody Target Details p53 Handling Images back to top
Application Notes Variations in protocols, secondaries and substrates may require the p53 antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,IHC (Frozen) only: 0.5-1.0 μg/mL for 30 minutes at RT
Restrictions For Research Use only

Handling

Product Details anti-p53 Antibody Target Details p53 Application Details Images back to top
Concentration 0.2 mg/mL
Buffer 0.2 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C,4 °C
Storage Comment Store the p53 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).