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|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||3 Antibodies|
|Flow Cytometry (FACS)||4 Antibodies|
|Immunochromatography (IC)||2 Antibodies|
|Immunocytochemistry (ICC)||11 Antibodies|
|Immunofluorescence (IF)||12 Antibodies|
|Immunofluorescence (fixed cells) (IF/ICC)||4 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||13 Antibodies|
|Immunohistochemistry (IHC)||44 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||18 Antibodies|
|Immunoprecipitation (IP)||16 Antibodies|
|Western Blotting (WB)||151 Antibodies|
|Antigen||Peroxiredoxin 1 (PRDX1) Antibodies|
|Epitope||AA 1-199, N-Term Alternatives|
|Conjugate||This Peroxiredoxin 1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-Peroxiredoxin 1 AntibodyTarget Details Peroxiredoxin 1 Application Details Handling References for anti-Peroxiredoxin 1 Antibody (ABIN452453) Images
|Specificity||The antibody recognizes Human Peroxiredoxin-1. Other species not tested.|
|Characteristics||Synonyms: PRDX-1, Prx1, Prx-1, PAG, NKEF-A, NKEFA PAGA, PAGB, TDPX2, Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2, Proliferation-associated gene protein,Natural killer cell-enhancing factor A|
|Purification||Protein-G affinity chromatography|
|Immunogen||Recombinant peroxiredoxin-1 (1-199 aa) purified from E. coli|
Target Details Peroxiredoxin 1Product Details anti-Peroxiredoxin 1 Antibody Application Details Handling References for anti-Peroxiredoxin 1 Antibody (ABIN452453) Images back to top
|Alternative Name||Peroxiredoxin-1 / PRDX1 (PRDX1 Antibody Abstract)|
|Background||PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. This protein is also known to be important to protect red blood cells against reactive oxygen species and in tumor prevention.Synonyms: NKEF-A, NKEFA PAGA, Natural killer cell-enhancing factor A, PAG, PAGB, PRDX-1, Proliferation-associated gene protein, Prx-1, Prx1, TDPX2, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2|
|Pathways||p53 Signaling, EGFR Signaling Pathway|
Application DetailsProduct Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Handling References for anti-Peroxiredoxin 1 Antibody (ABIN452453) Images back to top
ELISA. Western blot (1: 1,000 - 1: 2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details References for anti-Peroxiredoxin 1 Antibody (ABIN452453) Images back to top
|Buffer||PBS, pH 7.4, 0.09 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-Peroxiredoxin 1 Antibody (ABIN452453)Product Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details Handling Images back to top
Iraqui, Faye, Ragu, Masurel-Heneman, Kolodner, Huang: "Human peroxiredoxin PrxI is an orthologue of yeast Tsa1, capable of suppressing genome instability in Saccharomyces cerevisiae." in: Cancer research, Vol. 68, Issue 4, pp. 1055-63, 2008
Parmigiani, Xu, Venta-Perez, Erdjument-Bromage, Yaneva, Tempst, Marks: "HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 28, pp. 9633-8, 2008
Kim, Bogner, Baek, Ramnath, Liang, Kim, Andrews, Park: "Up-regulation of peroxiredoxin 1 in lung cancer and its implication as a prognostic and therapeutic target." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 8, pp. 2326-33, 2008
ImagesProduct Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details Handling References for anti-Peroxiredoxin 1 Antibody (ABIN452453) back to top