anti-Human Peroxiredoxin 1 antibody for Immunoprecipitation

Recommended Peroxiredoxin 1 Antibody (supplied by: Log in to see )

Antigen
Peroxiredoxin 1 (PRDX1) Antibodies
  • MGC80194
  • MGC84820
  • PRDX1
  • msp23
  • nkefa
  • pag
  • paga
  • pagb
  • prx-1
  • prx1
  • prxi
  • tdpx2
  • cb58
  • prdx1
  • wu:fq19b09
  • zgc:92891
  • 1274
  • CG1274
  • DPx-4156
  • DPx4156
  • Dmel\\CG1274
  • JafRac2
  • Jafrac-2
  • Prx4156
  • MSP23
  • NKEF-A
  • NKEFA
  • PAG
  • PAGA
  • PAGB
  • PRX1
  • PRXI
  • TDPX2
  • NkefA
  • OSF-3
  • OSF3
  • Paga
  • PrdxI
  • PrxI
  • TDX2
  • TPxA
  • Tdpx2
  • Hbp23
  • hm:zehl0637
  • zgc:110343
  • TPX-2
  • CBP
  • peroxiredoxin 1
  • peroxiredoxin 2
  • thioredoxin peroxidase 2
  • Thioredoxin peroxidase 2
  • peroxiredoxin 1-like
  • phosphoprotein associated with glycosphingolipid microdomains 1
  • prdx1
  • PRDX1
  • prdx2
  • Jafrac2
  • TPx2
  • PY02747
  • BCAN_B0712
  • BMEA_B0682
  • Prdx1
  • LOC100350232
  • PAG1
Epitope
AA 1-199
51
15
14
8
7
5
4
4
4
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
199
61
56
7
7
6
6
5
4
4
4
3
1
1
1
1
1
Host
Rabbit
107
78
23
Clonality
Polyclonal
Conjugate
This Peroxiredoxin 1 antibody is un-conjugated
13
13
9
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), ELISA, Western Blotting (WB)
170
106
52
21
19
16
15
13
9
5
5
4
2
1
Supplier
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Catalog No. ABIN1998417
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1686107 ICC IP WB Mouse IgG1 Log in to see 9D2
1 ABIN957795 IHC (p) IP ELISA WB Mouse IgG1, kappa Log in to see
1 ABIN1175811 ICC IHC IP WB Rabbit IgG AA 1-199 Log in to see Polyclonal
1 ABIN333079 IP ELISA Mouse IgG1, kappa Log in to see
1 ABIN333078 IP Mouse IgG1, kappa Log in to see
1 ABIN333053 ICC IP Mouse IgG1, kappa Log in to see
1 ABIN1825384 IP ELISA Mouse IgG1, kappa Log in to see 13E7
1 ABIN597054 IP ELISA Mouse IgG1, kappa Log in to see
1 ABIN1724475 IHC (p) IP ELISA WB Mouse IgG1 kappa Log in to see
1 ABIN2329456 IP Mouse IgG2b C-Term Log in to see PAG-C1
1 ABIN2340523 IP IHC ELISA WB Mouse IgG1 kappa Log in to see
1 ABIN2471664 IP IHC ELISA WB Mouse IgG1 kappa Log in to see
1 ABIN2329457 IP WB Rabbit AA 97-432 Log in to see Polyclonal
1 ABIN3039358 IP IHC WB Mouse IgG2b C-Term Log in to see
1 ABIN3039356 IP IHC WB Rabbit AA 97-432 Log in to see Polyclonal
1 ABIN5560370 ICC IP WB Mouse IgG1 Log in to see 9D2

General

Antigen Peroxiredoxin 1 (PRDX1) Antibodies
Epitope AA 1-199
(51), (15), (14), (8), (7), (5), (4), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(199), (61), (56), (7), (7), (6), (6), (5), (4), (4), (4), (3), (1), (1), (1), (1), (1)
Host Rabbit
(107), (78), (23)
Clonality
Polyclonal
Conjugate This Peroxiredoxin 1 antibody is un-conjugated
(13), (13), (9), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunoprecipitation (IP), ELISA, Western Blotting (WB)
(170), (106), (52), (21), (19), (16), (15), (13), (9), (5), (5), (4), (2), (1)
Pubmed 2 references available
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Product Details anti-Peroxiredoxin 1 Antibody

Target Details Peroxiredoxin 1 Application Details Handling References for anti-Peroxiredoxin 1 antibody (ABIN1998417) Images
Specificity Human Peroxiredoxin 1 / PRDX1
Characteristics Produced in rabbits immunized with purified, recombinant Human Peroxiredoxin 1 / PRDX1 (rh Peroxiredoxin 1 / PRDX1, ABIN2004075 NP_002565.1, Met 1-Lys 199,. Peroxiredoxin 1 / PRDX1 specific IgG was purified by Human Peroxiredoxin 1 / PRDX1 affinity chromatography.
Purification purified by affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Human Peroxiredoxin 1 / PRDX1 protein (ABIN2004075)
Isotype IgG

Target Details Peroxiredoxin 1

Product Details anti-Peroxiredoxin 1 Antibody Application Details Handling References for anti-Peroxiredoxin 1 antibody (ABIN1998417) Images back to top
Antigen
Alternative Name PRDX1 (PRDX1 Antibody Abstract)
Background Peroxiredoxin-1, also known as Thioredoxin peroxidase 2, Natural killer cell-enhancing factor A, PRDX1, and PAGA, is a member of the ahpC/TSA family. Peroxiredoxin-1 is constitutively expressed in most human cells. It is induced to higher levels upon serum stimulation in untransformed and transformed cells. Peroxiredoxins (PRDXs) are a family of antioxidant enzymes that are also known as scavengers of peroxide in mammalian cells. The overexpression of Peroxiredoxin-1, which is one of the peroxiredoxins that is a ubiquitously expressed protein, was related to a poor prognosis in several types of human cancers. Peroxiredoxin-1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-1 Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The reduced Peroxiredoxin-1 expression is an important factor in esophageal squamous cancer progression and could serve as a useful prognostic marker.
NCBI Accession NP_002565.1
Pathways p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events

Application Details

Product Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Handling References for anti-Peroxiredoxin 1 antibody (ABIN1998417) Images back to top
Application Notes WB: 2-10 μg/mL
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human PRDX1. The detection limit for Human PRDX1 is approximately 0.00245 ng/well.
IP: 4-6 μg/mg of lysate
Restrictions For Research Use only

Handling

Product Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details References for anti-Peroxiredoxin 1 antibody (ABIN1998417) Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

References for anti-Peroxiredoxin 1 antibody (ABIN1998417)

Product Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details Handling Images back to top
Background publications

Gisin, Perren, Bawohl, Jochum: "Rare allelic imbalances, but no mutations of the PRDX1 gene in human hepatocellular carcinomas." in: Journal of clinical pathology, Vol. 58, Issue 11, pp. 1229-31, 2005

Neumann, Krause, Carman, Das, Dubey, Abraham, Bronson, Fujiwara, Orkin, Van Etten: "Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression." in: Nature, Vol. 424, Issue 6948, pp. 561-5, 2003

Images

Product Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details Handling References for anti-Peroxiredoxin 1 antibody (ABIN1998417) back to top
Supplier Images
Western Blotting (WB) image for anti-Peroxiredoxin 1 (PRDX1) (AA 1-199) antibody (ABIN1998417) anti-Peroxiredoxin 1 (PRDX1) (AA 1-199) antibody
Immunoprecipitation (IP) image for anti-Peroxiredoxin 1 (PRDX1) (AA 1-199) antibody (ABIN1998417) anti-Peroxiredoxin 1 (PRDX1) (AA 1-199) antibody (Image 2)