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anti-Human PIDD antibody for Immunoprecipitation

Recommended PIDD Antibody (supplied by: Log in to see )

Antigen
P53-Induced Death Domain Protein (PIDD) Antibodies
  • 1200011D09Rik
  • AU042446
  • LRDD
  • Lrdd
  • Pidd
Epitope
AA 776-910
5
4
2
1
1
Reactivity
Human, Mouse (Murine)
36
24
18
Host
Rabbit
34
5
Clonality
Polyclonal
Conjugate
This PIDD antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
28
11
11
4
4
3
1
1
Supplier
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Catalog No. ABIN1169268
$ 257.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089579594 ABIN2963807 IP IHC WB Rabbit AA 776-910 Log in to see Polyclonal
0.00089579594 ABIN2335472 IP IHC WB Rabbit AA 776-910 Log in to see Polyclonal
0.00089579594 ABIN3059276 ICC IF IP IHC WB Rabbit Log in to see Polyclonal

Top referenced anti-PIDD antibody for Immunoprecipitation

Similar anti-PIDD Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 2 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies
Immunofluorescence (IF) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 7 Antibodies 12 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies 4 Antibodies
Immunoprecipitation (IP) 3 Antibodies 4 Antibodies
Western Blotting (WB) 14 Antibodies 26 Antibodies

General

Antigen P53-Induced Death Domain Protein (PIDD) Antibodies
Epitope AA 776-910
(5), (4), (2), (1), (1)
Reactivity Human, Mouse (Murine)
(36), (24), (18)
Host Rabbit
(34), (5)
Clonality
Polyclonal
Conjugate This PIDD antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(28), (11), (11), (4), (4), (3), (1), (1)
Pubmed 3 references available
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Product Details anti-PIDD Antibody

Target Details PIDD Application Details Handling References for anti-PIDD Antibody (ABIN1169268) Images
Specificity Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot.
Immunogen Recombinant human PIDD (Death Domain: aa 776-910).

Target Details PIDD

Product Details anti-PIDD Antibody Application Details Handling References for anti-PIDD Antibody (ABIN1169268) Images back to top
Antigen
Alternative Name PIDD (PIDD Antibody Abstract)
Background PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
Pathways p53 Signaling, Caspase Cascade in Apoptosis

Application Details

Product Details anti-PIDD Antibody Target Details PIDD Handling References for anti-PIDD Antibody (ABIN1169268) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-PIDD Antibody Target Details PIDD Application Details References for anti-PIDD Antibody (ABIN1169268) Images back to top
Format Liquid
Concentration 1 mg/ml
Buffer In PBS containing 10% glycerol and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months

References for anti-PIDD Antibody (ABIN1169268)

Product Details anti-PIDD Antibody Target Details PIDD Application Details Handling Images back to top
Product cited in:

Milleron, Bratton: "Heat shock induces apoptosis independently of any known initiator caspase-activating complex." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16991-7000, 2006

Janssens, Tinel, Lippens, Tschopp: "PIDD mediates NF-kappaB activation in response to DNA damage." in: Cell, Vol. 123, Issue 6, pp. 1079-92, 2005

Tinel, Tschopp: "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress." in: Science (New York, N.Y.), Vol. 304, Issue 5672, pp. 843-6, 2004