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anti-Mouse (Murine) PIDD antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PIDD Antibody (supplied by: Log in to see )

Antigen
P53-Induced Death Domain Protein (PIDD) Antibodies
  • 1200011D09Rik
  • AU042446
  • LRDD
  • Lrdd
  • Pidd
Reactivity
Human, Mouse (Murine), Rat (Rattus)
35
24
17
Host
Rabbit
34
4
Clonality
Polyclonal
Conjugate
This PIDD antibody is conjugated to HRP
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
27
11
11
4
4
2
1
1
Supplier
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Catalog No. ABIN905092
$ 379.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089245656 ABIN905096 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089245656 ABIN873247 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-PIDD Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 25 Antibodies 14 Antibodies 7 Antibodies
Immunoprecipitation (IP) 4 Antibodies 3 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies 3 Antibodies 3 Antibodies
Immunohistochemistry (IHC) 11 Antibodies 7 Antibodies 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 1 Antibodies 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies

General

Antigen P53-Induced Death Domain Protein (PIDD) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(35), (24), (17)
Host Rabbit
(34), (4)
Clonality
Polyclonal
Conjugate This PIDD antibody is conjugated to HRP
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(27), (11), (11), (4), (4), (2), (1), (1)
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Product Details anti-PIDD Antibody

Target Details PIDD Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human LRDD/PIDD
Isotype IgG

Target Details PIDD

Product Details anti-PIDD Antibody Application Details Handling Images back to top
Antigen
Alternative Name Lrdd (PIDD Antibody Abstract)
Background

The death domain (DD) containing protein PIDD is a p53 target gene in an erythroleukemia cell line that undergoes G1 phase arrest and subsequent apoptosis after p53 expression. Independently, PIDD was also described as a DD-containing protein with unknown function. The N-terminal region of PIDD contains seven leucine-rich repeats (LRRs), a protein interaction motif found in various proteins with diverse functions, followed by two ZU-5 domains and a C-terminal DD. PIDD forms a complex with caspase-2 and the adaptor protein RAIDD. Increased PIDD expression results in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli, via interaction with caspase-2 and CRADD/RAIDD. PIDD also promotes apoptosis downstream of p53 as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. PIDD has also been shown to interact with NEMO/IKBKG and RIP1 and enhance sumoylation and ubiquitination of NEMO/IKBKG, an important component for activation of the transcription factor NF-kappa-B.


Synonyms: Leucine rich repeats and death domain containing, Leucine-rich repeats and death domain containing, MGC16925, p53-induced protein with a death domain, PIDD, DKFZp434D229, PIDD_HUMAN.
Research Area Apoptosis/Necrosis
Pathways p53 Signaling, Caspase Cascade in Apoptosis

Application Details

Product Details anti-PIDD Antibody Target Details PIDD Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only

Handling

Product Details anti-PIDD Antibody Target Details PIDD Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.
Preservative Gentamicin sulfate
Precaution of Use This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at 4°C
Expiry Date 12 months