Browse our PIDD (PIDD) ELISA Kits

Full name:
P53-Induced Death Domain Protein ELISA Kits (PIDD)
On are 0 P53-Induced Death Domain Protein (PIDD) ELISA Kits from different suppliers available. Additionally we are shipping PIDD Antibodies (44) and PIDD Proteins (3) and many more products for this protein. A total of 51 PIDD products are currently listed.
1200011D09Rik, AU042446, Lrdd, Pidd
list all ELISA KIts Gene Name GeneID UniProt
Mouse PIDD PIDD 57913 Q9ERV7
Human PIDD PIDD 55367 Q9HB75
Rat PIDD PIDD 293625  

Show all synonyms

More ELISA Kits for PIDD Interaction Partners

Mouse (Murine) P53-Induced Death Domain Protein (PIDD) interaction partners

  1. NPM1 (show GJA1 ELISA Kits)-dependent nucleolar PIDDosome is a key initiator of the caspase-2 (show CASP2 ELISA Kits) activation cascade.

  2. PIDD acts as a critical switcher between the NF-kappabeta (show NFKB1 ELISA Kits) transcription pathway and radiation-induced apoptosis

  3. The tumor-modulatory effects of Caspase-2 (show CASP2 ELISA Kits) and Pidd1 do not require the scaffold protein (show HOMER1 ELISA Kits) Raidd (show CRADD ELISA Kits)

  4. Loss of PIDD leads to an impaired inflammatory response after DNA damage.

  5. Caspase 2 (show CASP2 ELISA Kits) activity can be induced in neurons from PIDD-null mice, and NGF (show NGFB ELISA Kits) deprivation or Abeta (show APP ELISA Kits) use caspase 2 (show CASP2 ELISA Kits) and RAIDD (show CRADD ELISA Kits) to execute death of these neurons.

  6. P450 (show POR ELISA Kits) levels were higher in female DES (show DES ELISA Kits)-treated p53 (show TP53 ELISA Kits)+/- mice compared to treated wild type mice.

  7. Results suggest that at least one alternative PIDDosome-independent mechanism of caspase-2 (show CASP2 ELISA Kits) activation exists in mammals in response to DNA damage.

  8. PIDD does not play an essential role for all p53 (show TP53 ELISA Kits)-mediated or p53 (show TP53 ELISA Kits)-independent apoptotic pathways.

Human P53-Induced Death Domain Protein (PIDD) interaction partners

  1. NPM1 (show NPM1 ELISA Kits)-dependent nucleolar PIDDosome is a key initiator of the caspase-2 (show CASP2 ELISA Kits) activation cascade.

  2. PIDD expression was lower in HCC (show FAM126A ELISA Kits) tissues and HCC (show FAM126A ELISA Kits) cell lines, compared with the adjacent non-tumorous tissues and LO2 normal hepatocytes. PIDD could serve as an independent prognostic factor to predict the survival of HCC (show FAM126A ELISA Kits) patients. PIDD facilitated cell cycle progression and accelerated cell proliferation in HepG2 cells, while overexpression of PIDD resulted in cell cycle arrest at G1 phase in Hep3B cells.

  3. By sequestering PIDD at the kinetochore, BubR1 (show BUB1B ELISA Kits) acts to delay PIDDosome formation until the next cycle, defining a new mechanism by which cells evade apoptosis during mitosis.

  4. The ATM (show ATM ELISA Kits) phosphorylation of the PIDD DD enables a binary switch through which cells elect to survive or die upon DNA injury.

  5. PIDD performs key functions upon UV irradiation, including TLS (show FUS ELISA Kits), NHEJ, NF-kappaB (show NFKB1 ELISA Kits) activation and cell death.

  6. Hsp90 (show HSP90 ELISA Kits) has a major role in controlling PIDD functional activity.

  7. a new splicing variant of PIDD named PIDD4 is reported.

  8. point mutations on RAIDD (show CRADD ELISA Kits) (R147E) and on PIDD (Y814A) exert a dominant negative effect on the formation of the PIDDosome, and that this effect cannot be applied after the PIDDosome has been formed

  9. Total caspase-2 (show CASP2 ELISA Kits) is upregulated during tumour progression in renal cell carcinomas.

  10. activation of caspase-2 (show CASP2 ELISA Kits) occurs in a complex that contains PIDD, whose expression is induced by p53 (show TP53 ELISA Kits), and RAIDD (show CRADD ELISA Kits); increased PIDD expression resulted in spontaneous activation of caspase-2 (show CASP2 ELISA Kits) and sensitization to apoptosis by genotoxic stimuli

PIDD Antigen Profile

Antigen Summary

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with PIDD

  • leucine-rich and death domain containing (Lrdd) Elisa Kit
  • p53-induced death domain protein (PIDD) Elisa Kit
  • p53-induced death domain protein (Pidd) Elisa Kit
  • 1200011D09Rik Elisa Kit
  • AU042446 Elisa Kit
  • Lrdd Elisa Kit
  • Pidd Elisa Kit

Protein level used designations for PIDD

leucine-rich repeat and death domain-containing protein , p53 protein induced, with death domain , p53-induced protein with a death domain , leucine-rich repeats and death domain containing

57913 Mus musculus
55367 Homo sapiens
293625 Rattus norvegicus
Did you look for something else?