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anti-Human PML antibody for Immunohistochemistry

Recommended PML Antibody (supplied by: Log in to see )

Antigen
Promyelocytic Leukemia (PML) Antibodies
  • 1200009E24Rik
  • AI661194
  • MYL
  • PML
  • PP8675
  • RGD1562602
  • RNF71
  • TRIM19
  • Trim19
Epitope
C-Term
13
11
9
9
8
7
7
5
3
3
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
108
25
7
1
Host
Rabbit
85
40
Clonality
Polyclonal
Conjugate
This PML antibody is un-conjugated
5
5
3
3
3
3
Application
Immunohistochemistry (IHC), Western Blotting (WB)
104
46
37
37
23
19
13
7
6
3
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN2777721
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.22487204 ABIN1533381 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.22487204 ABIN2707709 IC IF IHC WB Rabbit N-Term Log in to see Polyclonal
0.22487204 ABIN2499298 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.22487204 ABIN2495224 FACS IF IHC WB Rabbit Ig Fraction Sumoylation Site Log in to see Polyclonal
0.22487204 ABIN2404038 IF IHC WB Rabbit IgG Log in to see Polyclonal
0.0011312889 ABIN1874171 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011312889 ABIN252967 ICC IF IHC (p) IP IHC PLA WB Rabbit Log in to see Polyclonal
0.0011312889 ABIN1924810 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Internal Region, Sumoylation Site Log in to see Polyclonal
0.0011312889 ABIN1924813 IHC ELISA WB FITC Rabbit IgG Internal Region, Sumoylation Site Log in to see Polyclonal
0.0011312889 ABIN1924811 IHC ELISA WB APC Rabbit IgG Internal Region, Sumoylation Site Log in to see Polyclonal
0.0011312889 ABIN1924814 IHC ELISA WB PE Rabbit IgG Internal Region, Sumoylation Site Log in to see Polyclonal
0.0011312889 ABIN1924812 IHC ELISA WB Biotin Rabbit IgG Internal Region, Sumoylation Site Log in to see Polyclonal
0.0011312889 ABIN3021659 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011312889 ABIN252968 ICC IF IHC IP WB Rabbit AA 575-625 Log in to see Polyclonal
0.0011312889 ABIN1924815 IHC ELISA WB HRP Rabbit IgG Internal Region, Sumoylation Site Log in to see Polyclonal
0.0011312889 ABIN2891555 IF IHC WB Rabbit Pro39 Log in to see Polyclonal
0.0011312889 ABIN3186510 ELISA IF IHC WB Rabbit IgG N-Term Log in to see Polyclonal
0.0011312889 ABIN2337919 IHC ELISA WB APC Rabbit IgG Center Log in to see Polyclonal
0.0011312889 ABIN2337917 IHC ELISA WB Rabbit IgG Center Log in to see Polyclonal
0.0011312889 ABIN2337922 IHC ELISA WB HRP Rabbit IgG Center Log in to see Polyclonal

Similar anti-PML Antibodies

Application / Reactivity Mouse (Murine) Human Rat (Rattus)
Western Blotting (WB) 27 Antibodies 91 Antibodies 8 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Immunoprecipitation (IP) 8 Antibodies 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 20 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 39 Antibodies 9 Antibodies 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 1 Antibodies
Immunofluorescence (IF) 7 Antibodies 35 Antibodies 1 Antibodies

General

Antigen Promyelocytic Leukemia (PML) Antibodies
Epitope C-Term
(13), (11), (9), (9), (8), (7), (7), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(108), (25), (7), (1)
Host Rabbit
(85), (40)
Clonality
Polyclonal
Conjugate This PML antibody is un-conjugated
(5), (5), (3), (3), (3), (3)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(104), (46), (37), (37), (23), (19), (13), (7), (6), (3), (3), (3), (2), (1), (1), (1), (1)
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Product Details anti-PML Antibody

Target Details PML Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN981889
Sequence EGPSTLRVLD ENLADPQAED RPLVFFDLKI DNETQKISQL AAVNRESKFR
Specificity Isoform 1, 9, 10 and 11 specific
Predicted Reactivity Bovine : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Pig : 90 %, Guinea pig : 80 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against PML. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human PML

Target Details PML

Product Details anti-PML Antibody Application Details Handling Images back to top
Antigen
Alternative Name PML (PML Antibody Abstract)
Background PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions, all variants encode the same N-terminus.
Molecular Weight 59 kDa
Gene ID 5371
UniProt P29590
Research Area Cancer
Pathways p53 Signaling, Retinoic Acid Receptor Signaling Pathway

Application Details

Product Details anti-PML Antibody Target Details PML Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 540 AA

Restrictions For Research Use only

Handling

Product Details anti-PML Antibody Target Details PML Application Details Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-PML Antibody Target Details PML Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-PML antibody (Promyelocytic Leukemia) (C-Term) (ABIN2777721) anti-Promyelocytic Leukemia (PML) (C-Term) antibody
Immunohistochemistry (IHC) image for anti-PML antibody (Promyelocytic Leukemia) (C-Term) (ABIN2777721) anti-Promyelocytic Leukemia (PML) (C-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-PML antibody (Promyelocytic Leukemia) (C-Term) (ABIN2777721) anti-Promyelocytic Leukemia (PML) (C-Term) antibody (Image 3)