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anti-Mouse (Murine) PML antibody for Immunocytochemistry

Recommended PML Antibody (supplied by: Log in to see )

Antigen
Promyelocytic Leukemia (PML) Antibodies
  • 1200009E24Rik
  • AI661194
  • MYL
  • PML
  • PP8675
  • RGD1562602
  • RNF71
  • TRIM19
  • Trim19
Epitope
AA 1-581
13
11
9
9
8
7
6
5
3
3
3
2
2
1
1
1
1
1
Reactivity
Mouse (Murine)
111
25
8
1
Host
Mouse
88
39
Clonality
Monoclonal
Conjugate
This PML antibody is un-conjugated
5
5
3
3
3
3
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
105
46
39
37
23
20
12
7
6
3
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN2668256
$ 466.67
Plus shipping costs $45.00 and $21.00 dry ice
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010194078 ABIN212004 ICC WB Mouse IgG2b AA 1-581 Log in to see
0.0010194078 ABIN1818381 ICC WB Mouse IgG2b Log in to see 36-1-104
0.0010194078 ABIN2499299 IEM ICC IP WB Mouse IgG2b AA 1-581 Log in to see 36-1-104
0.0010194078 ABIN2667759 ICC IF IP WB Mouse IgG Log in to see 36-1-104
0.0010194078 ABIN2987115 ICC IF WB Mouse IgG Log in to see
0.0010194078 ABIN2989418 ICC IF IHC WB Rabbit IgG Log in to see Polyclonal
0.0010194078 ABIN1924800 GS ICC IP WB Mouse IgG2b AA 1-581 Log in to see

Top referenced anti-PML antibody for Immunocytochemistry

Similar anti-PML Antibodies

Application / Reactivity Mouse (Murine)
Electrophoretic Mobility-Shift Assay (EMSA) 1 Antibodies
ELISA 3 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Gel Shift (GS) 1 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunoelectron Microscopy (IEM) 1 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunohistochemistry (IHC) 9 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Western Blotting (WB) 27 Antibodies

General

Antigen Promyelocytic Leukemia (PML) Antibodies
Epitope AA 1-581
(13), (11), (9), (9), (8), (7), (6), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(111), (25), (8), (1)
Host Mouse
(88), (39)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PML antibody is un-conjugated
(5), (5), (3), (3), (3), (3)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(105), (46), (39), (37), (23), (20), (12), (7), (6), (3), (3), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-PML Antibody

Target Details PML Application Details Handling References for anti-PML Antibody (ABIN2668256) Images
Purification Protein G Chromatography
Immunogen This PML antibody was raised against a recombinant protein corresponding to amino acids 1-581 of mouse PML.
Clone 36-1-104
Isotype IgG

Target Details PML

Product Details anti-PML Antibody Application Details Handling References for anti-PML Antibody (ABIN2668256) Images back to top
Antigen
Alternative Name PML (PML Antibody Abstract)
Background PML (Promyelocytic Leukemia) protein is a transcription factor originally identified due to a chromosomal aberration fusing it to the Retinoic Acid Receptor alpha (RAR-A) in cases of Acute Promyelocytic Leukemia (APL). Besides transcriptional regulation, PML is involved in many processes, including the response to DNA damage, cell cycle regulation, viral infection response and apoptosis. These functions of PML involve the localization of PML to unique sub-nuclear structures called PML Nuclear Bodies (PML NBs). Over fifty proteins are know to be localized to PML NBs, either transiently or constitutively. These Nuclear Bodies are disrupted in PML knockout mice. PML is subject to a number of post-translational modifications, including phosphorylation, ubiquitylation and sumoylation.
Molecular Weight 110 kDa
Gene ID 18854
Research Area Cancer
Pathways p53 Signaling, Retinoic Acid Receptor Signaling Pathway

Application Details

Product Details anti-PML Antibody Target Details PML Handling References for anti-PML Antibody (ABIN2668256) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-PML Antibody Target Details PML Application Details References for anti-PML Antibody (ABIN2668256) Images back to top
Concentration 1 μg/μL
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20 °C for 2 years.
Expiry Date 6 months

References for anti-PML Antibody (ABIN2668256)

Product Details anti-PML Antibody Target Details PML Application Details Handling Images back to top
Product cited in:

Evdokimov, Sharma, Lockett, Lualdi, Kuehn: "Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3." in: Journal of cell science, Vol. 121, Issue Pt 24, pp. 4106-13, 2008