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anti-Mouse (Murine) PML antibody for Immunoprecipitation

Recommended PML Antibody (supplied by: Log in to see )

Antigen
Promyelocytic Leukemia (PML) Antibodies
  • 1200009E24Rik
  • AI661194
  • MYL
  • PML
  • PP8675
  • RGD1562602
  • RNF71
  • TRIM19
  • Trim19
Reactivity
Mouse (Murine)
109
25
8
1
Host
Mouse
86
39
Clonality
Monoclonal
Conjugate
This PML antibody is un-conjugated
5
5
3
3
3
3
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
104
46
38
36
23
19
12
7
6
3
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN567791
$ 346.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00090063456 ABIN2668256 ICC IF IP WB Mouse IgG AA 1-581 Log in to see 36-1-104 1
0.00090063456 ABIN187588 EMSA IF IP WB Mouse IgG2b AA 1-581 Log in to see 36-1-104
0.00090063456 ABIN2337907 IC IP WB Mouse IgG2b AA 1-581 Log in to see 6D676
0.00090063456 ABIN2499299 IEM ICC IP WB Mouse IgG2b AA 1-581 Log in to see 36-1-104
0.00090063456 ABIN2337930 IC IP IHC WB Mouse IgG2b Log in to see
0.00090063456 ABIN2667759 ICC IF IP WB Mouse IgG Log in to see 36-1-104
0.00090063456 ABIN1924800 GS ICC IP WB Mouse IgG2b AA 1-581 Log in to see

Top referenced anti-PML antibody for Immunoprecipitation

Similar anti-PML Antibodies

Application / Reactivity Mouse (Murine)
Electrophoretic Mobility-Shift Assay (EMSA) 1 Antibodies
ELISA 3 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Gel Shift (GS) 1 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunoelectron Microscopy (IEM) 1 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunohistochemistry (IHC) 9 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Western Blotting (WB) 27 Antibodies

General

Antigen Promyelocytic Leukemia (PML) Antibodies
Reactivity Mouse (Murine)
(109), (25), (8), (1)
Host Mouse
(86), (39)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PML antibody is un-conjugated
(5), (5), (3), (3), (3), (3)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(104), (46), (38), (36), (23), (19), (12), (7), (6), (3), (3), (3), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-PML Antibody

Target Details PML Application Details Handling References for anti-PML Antibody (ABIN567791) Images
Specificity This antibody reacts with Mouse PML (90-106 kDa) on Western blotting.
Purification Protein-A Agarose Chromatography of hybridoma supernatant.
Immunogen Recombinant full-length Mouse PML.
Clone 36-1-104
Isotype IgG2b

Target Details PML

Product Details anti-PML Antibody Application Details Handling References for anti-PML Antibody (ABIN567791) Images back to top
Antigen
Alternative Name PML / RNF71 (PML Antibody Abstract)
Background PML (promyelocytic leukemia) protein is a tripartite motif (TRIM)-containing nuclear phosphoprotein that functions as a transcription factor, a coactivator of nuclear receptors, a regulator of apoptosis, and as a growth and tumor suppressor. PML is localized to the nucleoplasm in distinct subnuclear structures referred to as Promyelocytic Leukemia Bodies (also known as Nuclear Domain 10). At least 14 splice variants of PML ranging in molecular weight from 48-97 kDa have been described. All isoforms of PML contain an identical N-terminus but vary in the C-terminal portion of the protein. PML is frequently overexpressed in Hodgkin's and Reed-Sternberg cells of Hodgkin's disease. PML is useful in studying acute promyelocytic leukemia which is characterized by fusion of PML and Retinoic Acid Receptor-alpha genes. The fusion protein blocks the terminal differentiation of hematopoietic cells and apoptosis.Synonyms: MYL, Probable transcription factor PML, RING finger protein 71, TRIM19, Tripartite motif-containing protein 19
Gene ID 18854
NCBI Accession NP_032910
UniProt Q60953
Pathways p53 Signaling, Retinoic Acid Receptor Signaling Pathway

Application Details

Product Details anti-PML Antibody Target Details PML Handling References for anti-PML Antibody (ABIN567791) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-PML Antibody Target Details PML Application Details References for anti-PML Antibody (ABIN567791) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 50 % Glycerol without preservatives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.

References for anti-PML Antibody (ABIN567791)

Product Details anti-PML Antibody Target Details PML Application Details Handling Images back to top
Background publications

Sone, Hayashi, Tarui, Agata, Takeichi, Nakagawa: "The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons." in: Journal of cell science, Vol. 120, Issue Pt 15, pp. 2498-506, 2007

Gaumont-Leclerc, Mukhopadhyay, Goumard, Ferbeyre: "PEA-15 is inhibited by adenovirus E1A and plays a role in ERK nuclear export and Ras-induced senescence." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46802-9, 2004

de Stanchina, Querido, Narita, Davuluri, Pandolfi, Ferbeyre, Lowe: "PML is a direct p53 target that modulates p53 effector functions." in: Molecular cell, Vol. 13, Issue 4, pp. 523-35, 2004

Images

Product Details anti-PML Antibody Target Details PML Application Details Handling References for anti-PML Antibody (ABIN567791) back to top
Supplier Images
Immunofluorescence (IF) image for anti-PML antibody (Promyelocytic Leukemia) (ABIN567791) anti-Promyelocytic Leukemia (PML) antibody
Western Blotting (WB) image for anti-PML antibody (Promyelocytic Leukemia) (ABIN567791) anti-Promyelocytic Leukemia (PML) antibody (Image 2)