anti-Human SERPINE1 antibody for Neutralization

Recommended SERPINE1 Antibody (supplied by: Log in to see )

Antigen
serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) Antibodies
  • PAI
  • PAI-1
  • PAI1
  • PLANH1
  • si:ch211-138a11.1
  • SERPINE1
  • Planh1
  • B230326M24Rik
  • PI-7
  • PI7
  • PN-1
  • Spi4
  • HsT1201
  • PAI-2
  • PAI2
  • PLANH2
  • PAI1A
  • Pai1
  • Pai1aa
  • Planh
  • RATPAI1A
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • plasminogen activator inhibitor 1
  • plasminogen activator inhibitor type 1
  • serine (or cysteine) peptidase inhibitor, clade E, member 1
  • serine (or cysteine) peptidase inhibitor, clade E, member 2
  • serpin peptidase inhibitor, clade B (ovalbumin), member 2
  • serpine1
  • SERPINE1
  • CpipJ_CPIJ011718
  • CpipJ_CPIJ016298
  • PAI-1
  • Serpine1
  • Serpine2
  • SERPINB2
Epitope
AA 21-402
38
18
15
13
11
9
9
7
7
5
5
5
5
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
364
136
129
41
18
13
7
6
4
4
3
2
2
2
1
1
Host
Goat
261
126
54
26
2
1
Clonality
Polyclonal
Conjugate
This SERPINE1 antibody is un-conjugated
44
30
17
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
331
216
119
73
44
43
36
27
27
26
19
18
10
6
6
6
5
4
4
4
3
3
1
1
1
1
1
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Available images

Catalog No. ABIN958257
$ 815.83
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1104210 IHC (p) Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2565045 IHC (fro) Neut ELISA WB Mouse IgG1 AA 110-145 Log in to see
1 ABIN1983426 Neut WB Mouse IgG1 AA 21-402 Log in to see MM0542-12V3

General

Antigen serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) Antibodies
Epitope AA 21-402
(38), (18), (15), (13), (11), (9), (9), (7), (7), (5), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(364), (136), (129), (41), (18), (13), (7), (6), (4), (4), (3), (2), (2), (2), (1), (1)
Host Goat
(261), (126), (54), (26), (2), (1)
Clonality
Polyclonal
Conjugate This SERPINE1 antibody is un-conjugated
(44), (30), (17), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
(331), (216), (119), (73), (44), (43), (36), (27), (27), (26), (19), (18), (10), (6), (6), (6), (5), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1)
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Product Details anti-SERPINE1 Antibody

Target Details SERPINE1 Application Details Handling Images
Specificity Detects human Serpin E1/PAI-1 in direct ELISAs and Western blots. In direct ELISAs, less than 2 % cross-reactivity with recombinant human.
Purification Immunoaffinity purified
Sterility 0.2 μm filtered
Immunogen S. frugiperda insect ovarian cell line Sf21-derived recombinant human Serpin E1/PAI-1 Gly21-Pro402 Accession # P05121.

Type of Immunogen: Recombinant protein
Isotype IgG

Target Details SERPINE1

Product Details anti-SERPINE1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SERPINE1 / PAI-1 (SERPINE1 Antibody Abstract)
Background Name/Gene ID: SERPINE1
Family: Serine Protease Inhibitor

Synonyms: SERPINE1, PAI1, PLANH1, PAI-1, Serpin E1
Gene ID 5054
UniProt P05121
Pathways p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration

Application Details

Product Details anti-SERPINE1 Antibody Target Details SERPINE1 Handling Images back to top
Application Notes Approved: IHC-P (5 - 15 μg/mL), IP (25 μg/mL), Neut, WB (0.1 μg/mL)

Usage: Western Blot, 0.1 μg/mL, Recombinant Human Serpin E1/PAI-1. Immunohistochemistry, 5-15 μg/mL. Immunoprecipitation, 25 μg/mL, Conditioned cell culture medium spiked with Recombinant Human Serpin E1/PAI-1. Neutralization, Measured by its ability to neutralize Recombinant Human Serpin E1 (1.8 μg/mL) inhibition of. Recombinant Human u-Plasminogen Activator (uPA)/Urokinase (0.1 μg/mL) cleavage of the fluorogenic peptide substrate Z-GGR-AMC (100 uM). The Neutralization Dose (ND50) is typically 10 μg/mL.
Restrictions For Research Use only

Handling

Product Details anti-SERPINE1 Antibody Target Details SERPINE1 Application Details Images back to top
Format Lyophilized
Reconstitution Sterile PBS. Resuspend to 500 μL
Concentration Lot specific
Buffer Lyophilized from 0.2 um filtered solution in PBS, trehalose
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C
Short term: +4°C
Avoid freeze-thaw cycles.

Images

Product Details anti-SERPINE1 Antibody Target Details SERPINE1 Application Details Handling back to top
Supplier Images
 image for anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) (AA 21-402) antibody (ABIN958257) anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) (AA 21-402) antibody