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Browse our SERPINE1 (SERPINE1) ELISA Kits

Full name:
serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 ELISA Kits (SERPINE1)
On www.antibodies-online.com are 115 serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) ELISA Kits from 22 different suppliers available. Additionally we are shipping SERPINE1 Antibodies (444) and SERPINE1 Proteins (152) and many more products for this protein. A total of 733 SERPINE1 products are currently listed.
Synonyms:
B230326M24Rik, HsT1201, PAI, PAI-1, PAI-2, Pai1, PAI1A, Pai1aa, PAI2, PI-7, PI7, Planh, Planh1, PLANH2, PN-1, RATPAI1A, SERPINE1, si:ch211-138a11.1, Spi4
list all ELISA KIts Gene Name GeneID UniProt
SERPINE1 18787  
SERPINE1 5055 P05120
SERPINE1 24617 P20961

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Top referenced SERPINE1 ELISA Kits

  1. ABIN612647 : Coker, Thomas, Clair, Hendrick, Krombach, Galis, Spinale: Myocardial matrix metalloproteinase activity and abundance with congestive heart failure. in The American journal of physiology 1998 (PubMed)
    Show all 3 references for ABIN612647

  2. Mouse (Murine) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN415629 : Kim, Hong, Eom, Lee, Park: Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice. in Breast cancer research and treatment 2011 (PubMed)
    Show all 2 references for ABIN415629

  3. Human SERPINE1 ELISA Kit for Sandwich ELISA - ABIN415046 : Topaloglu, Arslan, Karakose, Ucan, Ginis, Cakir, Akkaymak, Sahin, Ozbek, Cakal, Delibasi: Is there any association between thrombosis and tissue factor pathway inhibitor levels in patients with vitamin D deficiency? in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2015 (PubMed)

  4. Rat (Rattus) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN416381 : Olatunji, Usman, Seok, Kim: Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder. in Archives of physiology and biochemistry 2016 (PubMed)

More ELISA Kits for SERPINE1 Interaction Partners

Xenopus laevis serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) interaction partners

  1. The serpin PN1 (show SCN9A ELISA Kits) is a feedback regulator of FGF signaling in germ layer and primary axis formation.

Zebrafish serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) interaction partners

  1. SERPINe1-derived 14-mer (show MERTK ELISA Kits) peptide and low molecular weight drugs targeting SERPINe1 (i.e. tannic acid, EGCG, tiplaxtinin) inhibited in vitro infections not only of viral haemorrhagic septicemia virus, but also of other fish rhabdoviruses.

  2. X-ray crystal structure analysis of glycosylated fish PAI-1 confirmed the presence of an N-linked glycan in the gate region and a lack of glycan-induced structural changes.

Mouse (Murine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) interaction partners

  1. PAI-1 inhibitor PAI-039 prevents smooth muscle cell migration and neointimal hyperplasia.

  2. Tongqiaohuoxue decoction exerted an anti-thrombotic effect through the regulation of PAI-1 and fibrinolysis.

  3. PAI-1 plays a role in maintaining gastric mucosal organization in hypergastrinemia.

  4. Olmesartan did not significantly affect PAI1 levels in this mouse model

  5. BRD2 (show BRD2 ELISA Kits) is involved in the modulation of neuroinflammatory responses through PAI-1 and via the regulation of epigenetic reader BET protein

  6. the involvement of PAI-1 in HIF-1 (show HIF1A ELISA Kits)-enhanced thrombosis and that an additional factor participates in regulating Pai-1 expression in compressed skin.

  7. Neutralization of the antifibrinolytic function of PAI-1 resolves skin fibrosis by limiting the extent of initial vascular injury and connective tissue inflammation.

  8. These results suggest the critical physiological role of TRL4-Fyn (show FYN ELISA Kits) interaction in the modulation of PAI-1-tPA (show PLAT ELISA Kits) axis in astrocytes during neuroinflammatory responses such as ischemia/reperfusion injuries.

  9. aberrant Serpine2/Pn-1 (show SERPINE2 ELISA Kits) is required for proliferation of human and mouse medulloblastoma cells.

  10. PAI-1 can promote cell migration via LRP1 (show LRP1 ELISA Kits)-dependent activation of the beta-catenin (show CTNNB1 ELISA Kits) and ERK1/2 (show MAPK1/3 ELISA Kits) MAPK (show MAPK1 ELISA Kits) pathway

Human serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) interaction partners

  1. We show that PAI-1 expression is significantly increased in the esophagi of patients with active eosinophilic esophagitis (EoE) compared with nondiseased esophagi and that EoE-directed therapy reduces the degree of PAI-1 expression. We further demonstrate that TGF-beta1 (show TGFB1 ELISA Kits) increases PAI-1 expression in primary human esophageal epithelial cells and fibroblasts from patients with EoE

  2. Higher plasma concentrations of a-2-AP and PAI-1 in patients with OSA indicated that these patients had increased prothrombotic activity. OSA increases the risk of cardiovascular complications as it enhances prothrombotic activity.

  3. The SERPINE1 -675 polymorphism, but not SERPINE1 -844 polymorphism, was associated with susceptibility to chronic obstructive pulmonary disease in a Chinese Han population.

  4. Increasing cell density is a negative regulator of proliferation and PAI-1 secretion both in normal and Graves' orbitopathy orbital fibroblasts; these negative regulatory effects are partially reversed in the presence of TGF-beta1 (show TGFB1 ELISA Kits).

  5. Fetal 4G/4G PAI-1 (OR, 0.63; 95% confidence interval, 0.43e0.91) was associated with decreased odds of stillbirth.

  6. PAI-1 4G/5G polymorphism was not significantly associated with schizophrenia.

  7. Cu(II) produces an increase in dynamics in regions important for the function and overall stability of PAI-1, while the somatomedin B (show VTN ELISA Kits) domain elicits virtually the opposite effect. A mutant form of PAI-1 lacking two N-terminal histidine residues at positions 2 and 3 exhibits similar increases in dynamics upon Cu(II) binding compared to that of active wild-type PAI-1.

  8. The N3 subdomain of FnBPB contains the full plasminogen (show PLG ELISA Kits)-binding site, and this includes, at least in part, two conserved patches of surface-located lysine residues that were recognized by kringle 4 of the host protein.

  9. The novel finding is the identification of several PAI-1 genetic variants that increase susceptibility to Osteoporotic Vertebral Compression Fractures .

  10. High levels of PAI-1 and low levels of VDR (show CYP27B1 ELISA Kits) expression were significantly associated with an increased risk for keloid disease in Chinese patients.

Pig (Porcine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) interaction partners

  1. In one pig population and in female pigs, SERPINE1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1) was significantly associated with muscling, growth and fat accretion and in male animals with meat quality.

Cow (Bovine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) interaction partners

  1. Data show that urokinase-type plasminogen activator (uPA (show PLAU ELISA Kits)) is only expressed in the cumulus cells of immature and in vitro matured cumulus-oocyte complexes (COCs), while uPA (show PLAU ELISA Kits) receptor (uPAR (show PLAUR ELISA Kits)) and plasminogen activator inhibitor-1 (PAI-1) are expressed in both the cumulus cells and the immature and in vitro matured oocytes.

  2. Data suggest PAI1 plays key role in modulating chromaffin cell neurosecretory function. Evidence is presented that in chromaffin cells, PAI1 is targeted to storage vesicles and co-released with catecholamine upon secretagogue/stress stimulation.

  3. the PI3K/Akt (show AKT1 ELISA Kits) pathway acts as a negative regulator of PAI-1 expression in vascular endothelial cells, in part, through the downregulation of MAPK (show MAPK1 ELISA Kits) pathways

  4. high glucose-induced plasminogen activator inhibitor-1 (PAI-1) expression in endothelial cells is mediated by NF-kappaB (show NFKB1 ELISA Kits) activation through the Rho/Rho-kinase (show ROCK1 ELISA Kits) pathway

  5. FoxO1 (show FOXO1 ELISA Kits) inhibits PAI-1 expression through the inhibition of TGF-beta (show TGFB1 ELISA Kits)/Smad (show SMAD1 ELISA Kits)-mediated signaling pathways.

SERPINE1 Antigen Profile

Antigen Summary

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SERPINE1

  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (serpine1) Elisa Kit
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1) Elisa Kit
  • plasminogen activator inhibitor 1 (CpipJ_CPIJ011718) Elisa Kit
  • plasminogen activator inhibitor 1 (CpipJ_CPIJ016298) Elisa Kit
  • plasminogen activator inhibitor type 1 (PAI-1) Elisa Kit
  • serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1) Elisa Kit
  • serine (or cysteine) peptidase inhibitor, clade E, member 2 (Serpine2) Elisa Kit
  • serpin peptidase inhibitor, clade B (ovalbumin), member 2 (SERPINB2) Elisa Kit
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (Serpine1) Elisa Kit
  • B230326M24Rik Elisa Kit
  • HsT1201 Elisa Kit
  • PAI Elisa Kit
  • PAI-1 Elisa Kit
  • PAI-2 Elisa Kit
  • Pai1 Elisa Kit
  • PAI1A Elisa Kit
  • Pai1aa Elisa Kit
  • PAI2 Elisa Kit
  • PI-7 Elisa Kit
  • PI7 Elisa Kit
  • Planh Elisa Kit
  • Planh1 Elisa Kit
  • PLANH2 Elisa Kit
  • PN-1 Elisa Kit
  • RATPAI1A Elisa Kit
  • SERPINE1 Elisa Kit
  • si:ch211-138a11.1 Elisa Kit
  • Spi4 Elisa Kit

Protein level used designations for SERPINE1

PAI 1 , serine (or cysteine) proteinase inhibitor, clade E, member 1 , chemokine CCL-C25s , plasminogen activator inhibitor 1 , serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 , plasminogen activator inhibitor 1-like , PAI , Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI) , endothelial plasminogen activator inhibitor , nexin, plasminogen activator inhibitor type 1 , plasminogen activator inhibitor, type I , serpin E1 , GDN , glia-derived nexin , peptidase inhibitor 7 , protease nexin 1 , protease nexin I , serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 , serine (or cysteine) proteinase inhibitor, clade E, member 2 , serine protease inhibitor 4 , serine protease-inhibitor 4 , serpin E2 , monocyte Arg-serpin , placental plasminogen activator inhibitor , plasminogen activator inhibitor 2 , plasminogen activator inhibitor, type II (arginine-serpin) , serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 , serpin B2 , urokinase inhibitor , serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 , PAI-1 , serine (or cysteine) peptidase inhibitor, clade E, member 1 , serine (or cysteine) proteinase inhibitor, member 1 , plasminogen activator inhibitor I , plasminogen activator inhibitor, type 1 , putative plasminogen activator inhibitor-1 , plasminogen activator inhibitor type 1

GENE ID SPECIES
779433 Xenopus laevis
100136840 Danio rerio
713883 Macaca mulatta
472467 Pan troglodytes
100127732 Xenopus (Silurana) tropicalis
100385528 Callithrix jacchus
100435876 Pongo abelii
100588010 Nomascus leucogenys
6045186 Culex quinquefasciatus
6050005 Culex quinquefasciatus
100381267 Ovis aries
18787 Mus musculus
20720 Mus musculus
5055 Homo sapiens
5054 Homo sapiens
24617 Rattus norvegicus
396945 Sus scrofa
281375 Bos taurus
100009588 Oryctolagus cuniculus
403476 Canis lupus familiaris
100725387 Cavia porcellus
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