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Mouse (Murine) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN2010725
Chang: Cilostazol inhibits HMGB1 release in LPS-activated RAW 264.7 cells and increases the survival of septic mice. in Thrombosis research 2015
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Mouse (Murine) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN2010772
Eren, Boe, Murphy, Place, Nagpal, Morales-Nebreda, Urich, Quaggin, Budinger, Mutlu, Miyata, Vaughan: PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. in Proceedings of the National Academy of Sciences of the United States of America 2014
Show all 32 Pubmed References
Human SERPINE1 ELISA Kit for Sandwich ELISA - ABIN2010722
Balc? Ekmekçi, Ekmekçi, Güngör, Tüten, Toprak, Korkmaz, Öncül, Çal??kan, Kucur, Donma, Madazl?, Sönmez: Evaluation of Lp-PLA2 mass, vitronectin and PAI-1 activity levels in patients with preeclampsia. in Archives of gynecology and obstetrics 2015
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Rat (Rattus) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN2010733
Zou, Devi, Sparkenbaugh, Younis, Roth, Ganey: Hepatotoxic interaction of sulindac with lipopolysaccharide: role of the hemostatic system. in Toxicological sciences : an official journal of the Society of Toxicology 2009
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Pig (Porcine) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN2010729
Duburcq, Tournoys, Viviane, Hubert, Gmyr, Pattou, Jourdain: Impact of Obesity on Endotoxin-Induced Disseminated Intravascular Coagulation. in Shock (Augusta, Ga.) 2015
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Human SERPINE1 ELISA Kit for Sandwich ELISA - ABIN612750
Johansson, Sørensen, Perner, Welling, Wanscher, Larsen, Ostrowski: High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality. in Journal of thrombosis and haemostasis : JTH 2012
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Rat (Rattus) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN416381
Olatunji, Usman, Seok, Kim: Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder. in Archives of physiology and biochemistry 2016
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Rabbit SERPINE1 ELISA Kit for Sandwich ELISA - ABIN2010731
Florova, Azghani, Karandashova, Schaefer, Koenig, Stewart-Evans, Declerck, Idell, Komissarov: Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits. in American journal of respiratory cell and molecular biology 2015
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Pig (Porcine) SERPINE1 ELISA Kit for Sandwich ELISA - ABIN2010780
Thorgersen, Hellerud, Nielsen, Barratt-Due, Fure, Lindstad, Pharo, Fosse, Tønnessen, Johansen, Castellheim, Mollnes: CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010
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Human SERPINE1 ELISA Kit for Sandwich ELISA - ABIN415046
Topaloglu, Arslan, Karakose, Ucan, Ginis, Cakir, Akkaymak, Sahin, Ozbek, Cakal, Delibasi: Is there any association between thrombosis and tissue factor pathway inhibitor levels in patients with vitamin D deficiency? in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2015
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The serpin PN1 (show SCN9A ELISA Kits) is a feedback regulator of FGF signaling in germ layer and primary axis formation.
a highly dynamic endocardium in the regenerating zebrafish heart, with two key endocardial players, Serpine1 and Notch (show NOTCH1 ELISA Kits) signalling, regulating crucial regenerative processes, is reported.
SERPINe1-derived 14-mer (show MERTK ELISA Kits) peptide and low molecular weight drugs targeting SERPINe1 (i.e. tannic acid, EGCG, tiplaxtinin) inhibited in vitro infections not only of viral haemorrhagic septicemia virus, but also of other fish rhabdoviruses.
X-ray crystal structure analysis of glycosylated fish PAI-1 confirmed the presence of an N-linked glycan in the gate region and a lack of glycan-induced structural changes.
the role of the antifibrinolytic protein plasminogen activator inhibitor-1 (PAI-1) in alcohol enhancement of experimental endotoxin-induced acute lung injury, is reported.
These data uncover a novel mechanism whereby loss of serine protease (show F2 ELISA Kits) inhibition leads to lung lymphocyte accumulation.
PAI-1 inhibitor PAI-039 prevents smooth muscle cell migration and neointimal hyperplasia.
Tongqiaohuoxue decoction exerted an anti-thrombotic effect through the regulation of PAI-1 and fibrinolysis.
PAI-1 plays a role in maintaining gastric mucosal organization in hypergastrinemia.
Olmesartan did not significantly affect PAI1 levels in this mouse model
BRD2 (show BRD2 ELISA Kits) is involved in the modulation of neuroinflammatory responses through PAI-1 and via the regulation of epigenetic reader BET protein
the involvement of PAI-1 in HIF-1 (show HIF1A ELISA Kits)-enhanced thrombosis and that an additional factor participates in regulating Pai-1 expression in compressed skin.
Neutralization of the antifibrinolytic function of PAI-1 resolves skin fibrosis by limiting the extent of initial vascular injury and connective tissue inflammation.
These results suggest the critical physiological role of TRL4-Fyn (show FYN ELISA Kits) interaction in the modulation of PAI-1-tPA (show PLAT ELISA Kits) axis in astrocytes during neuroinflammatory responses such as ischemia/reperfusion injuries.
This study is the first to associate enhancer RNAs with SERPINB2 and is the first demonstration of acquisition of NELF (show NELF ELISA Kits) binding by enhancer RNAs on chromatin.
Mitochondria-targeted esculetin has anti-atherosclerotic effects by inhibiting PAI-1 levels by modulating miR (show MLXIP ELISA Kits)-19b and -30c expression and affecting SIRT3 (show SIRT3 ELISA Kits)- and STAT3 (show STAT3 ELISA Kits)-mediated signaling pathways.
Serum levels of PAI-1 are higher in patients with COPD (show ARCN1 ELISA Kits) and that moderate-to-severe airflow limitation, hypertriglyceridemia, and systemic inflammation are independent predictors of an elevated PAI-1 level.
SERPINE1 gene polymorphisms were associated with delayed cerebral ischemia and functional outcome after aneurysmal subarachnoid hemorrhage.
There was a statistically significant difference between heterozygous PAI-1 in women with only 1 spontaneous miscarriages compared to the control group.
This study establishes a novel role for SerpinB2 in the stromal compartment in pancreatic ductal adenocarcinoma invasion through regulation of stromal remodelling
SERPINE1 suppress hepatitis C virus replication possibly by negatively regulating TGF-beta (show TGFB1 ELISA Kits) signaling.
elevated serum PAI-1 levels are related to the lung function decline, systemic inflammation, and small airway obstruction in COPD (show ARCN1 ELISA Kits), suggesting that PAI-1 may play critical roles in the pathogenesis of COPD (show ARCN1 ELISA Kits).
We found significant difference between Grade 1 and Grade 2+3 patients in terms of the PAI-1 levels (P = 0.047). There was no association between PAI-1 4G/5G polymorphism and the grades of endometrial cancer (P = 0.993). Our data suggest that the level of PAI-1 and PAI-1 4G/5G gene polymorphism are effective in the formation of endometrial cancer. PAI-1 levels are also associated with the grades of endometrial cancer.
PAI-1 overexpression is associated with Malignant Pleural Mesothelioma.
In one pig population and in female pigs, SERPINE1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1) was significantly associated with muscling, growth and fat accretion and in male animals with meat quality.
Data show that urokinase-type plasminogen activator (uPA (show PLAU ELISA Kits)) is only expressed in the cumulus cells of immature and in vitro matured cumulus-oocyte complexes (COCs), while uPA (show PLAU ELISA Kits) receptor (uPAR (show PLAUR ELISA Kits)) and plasminogen activator inhibitor-1 (PAI-1) are expressed in both the cumulus cells and the immature and in vitro matured oocytes.
Data suggest PAI1 plays key role in modulating chromaffin cell neurosecretory function. Evidence is presented that in chromaffin cells, PAI1 is targeted to storage vesicles and co-released with catecholamine upon secretagogue/stress stimulation.
the PI3K/Akt (show AKT1 ELISA Kits) pathway acts as a negative regulator of PAI-1 expression in vascular endothelial cells, in part, through the downregulation of MAPK (show MAPK1 ELISA Kits) pathways
high glucose-induced plasminogen activator inhibitor-1 (PAI-1) expression in endothelial cells is mediated by NF-kappaB (show NFKB1 ELISA Kits) activation through the Rho/Rho-kinase (show ROCK1 ELISA Kits) pathway
FoxO1 (show FOXO1 ELISA Kits) inhibits PAI-1 expression through the inhibition of TGF-beta (show TGFB1 ELISA Kits)/Smad (show SMAD1 ELISA Kits)-mediated signaling pathways.
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, serine (or cysteine) proteinase inhibitor, clade E, member 1
, chemokine CCL-C25s
, plasminogen activator inhibitor 1
, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
, plasminogen activator inhibitor 1-like
, Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)
, endothelial plasminogen activator inhibitor
, nexin, plasminogen activator inhibitor type 1
, plasminogen activator inhibitor, type I
, serpin E1
, glia-derived nexin
, peptidase inhibitor 7
, protease nexin 1
, protease nexin I
, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
, serine (or cysteine) proteinase inhibitor, clade E, member 2
, serine protease inhibitor 4
, serine protease-inhibitor 4
, serpin E2
, monocyte Arg-serpin
, placental plasminogen activator inhibitor
, plasminogen activator inhibitor 2
, plasminogen activator inhibitor, type II (arginine-serpin)
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
, serpin B2
, urokinase inhibitor
, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
, serine (or cysteine) peptidase inhibitor, clade E, member 1
, serine (or cysteine) proteinase inhibitor, member 1
, plasminogen activator inhibitor I
, plasminogen activator inhibitor, type 1
, putative plasminogen activator inhibitor-1
, plasminogen activator inhibitor type 1