anti-Mouse (Murine) TANK antibody for Enzyme Immunoassay

Recommended TANK Antibody (supplied by: Log in to see )

Antigen
TRAF Family Member-Associated NFKB Activator (TANK) Antibodies
  • C86182
  • E430026L09Rik
  • I-TRAF
  • ITRAF
  • TRAF2
  • TRAF family member-associated NFKB activator
  • TRAF family member-associated Nf-kappa B activator
  • TANK
  • Tank
Epitope
C-Term
21
18
14
13
10
5
4
3
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
120
47
43
11
7
6
5
5
4
4
2
2
1
Host
Rabbit
114
3
2
1
1
Clonality
Polyclonal
Conjugate
This TANK antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
107
45
35
25
16
15
14
13
10
3
2
2
1
Supplier
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Catalog No. ABIN5555293
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN272299 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal

General

Antigen TRAF Family Member-Associated NFKB Activator (TANK) Antibodies
Epitope C-Term
(21), (18), (14), (13), (10), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(120), (47), (43), (11), (7), (6), (5), (5), (4), (4), (2), (2), (1)
Host Rabbit
(114), (3), (2), (1), (1)
Clonality
Polyclonal
Conjugate This TANK antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(107), (45), (35), (25), (16), (15), (14), (13), (10), (3), (2), (2), (1)
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Product Details anti-TANK Antibody

Target Details TANK Application Details Handling Images
Specificity This antibody detects TANK / ITRAF at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Peptide Affinity Chromatography
Immunogen 14 amino acid peptide from near the carboxy terminus of Human TANK.
Isotype IgG

Target Details TANK

Product Details anti-TANK Antibody Application Details Handling Images back to top
Antigen
Alternative Name TANK / ITRAF (TANK Antibody Abstract)
Background TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. This activation of NF-kappaB occurs through an association with the kinases IKKepsilon and TBK1. More recently, it was shown that these proteins can then form a complex with NEMO, a protein that regulates the activity of the IkappaB complex. This suggests that in addition to the possibility that TBK1 and IKKepsilon activate the IKKs, the association with the IKK complex may help these kinases modulate other functions, such as the transactivation potential of NF-kappaB proteins. At least two isoforms of TANK are known to exist.Synonyms: I-TRAF, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF2
Gene ID 10010
NCBI Accession NP_004171
Pathways p53 Signaling, TLR Signaling, Activation of Innate immune Response

Application Details

Product Details anti-TANK Antibody Target Details TANK Handling Images back to top
Application Notes ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TANK Antibody Target Details TANK Application Details Images back to top
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.