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anti-Human TNFRSF10B antibody for Flow Cytometry

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • cd262
  • CD262
  • dr5
  • DR5
  • killer
  • KILLER
  • KILLER/DR5
  • Ly98
  • MK
  • TNFRSF10B
  • TRAIL-R2
  • TRAILR2
  • trailr2
  • TRICK2
  • trick2
  • TRICK2A
  • trick2a
  • trick2b
  • TRICK2B
  • trickb
  • TRICKB
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • ZTNFR9
Reactivity
Human
322
73
20
1
1
1
Host
Mouse
181
165
11
9
6
2
Clonality
Monoclonal
Conjugate
This TNFRSF10B antibody is conjugated to PE
23
21
16
6
5
5
5
5
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS)
191
165
73
44
41
34
25
23
16
14
13
5
4
3
3
1
1
Supplier
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Catalog No. ABIN2663241
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.28290245 ABIN2658556 FACS ICFC APC Mouse IgG1 kappa Log in to see DJR2-4 (7-8) 8
0.28290245 ABIN2664459 FACS Mouse IgG1 kappa Log in to see DJR2-4 (7-8) 8
0.28290245 ABIN2664458 FACS Mouse IgG1 kappa Log in to see DJR2-2 (2-6) 9
0.28290245 ABIN1996884 FACS PE Rabbit IgG AA 1-182 Log in to see 102
0.28290245 ABIN1996881 FACS ELISA Rabbit IgG AA 1-182 Log in to see 102
0.28290245 ABIN4898057 FACS Alexa Fluor 647 Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898047 FACS Allophycocyanin Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898048 FACS Allophycocyanin Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898049 FACS PerCP Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898050 FACS PerCP Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898051 FACS Alexa Fluor 488 Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898052 FACS Alexa Fluor 488 Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898053 FACS Alexa Fluor 700 Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898054 FACS Alexa Fluor 700 Mouse IgG2b AA 56-182 Log in to see 71908
0.28290245 ABIN4898055 FACS PE Mouse IgG2b AA 56-182 Log in to see 71908 13
0.28290245 ABIN4898056 FACS PE Mouse IgG2b AA 56-182 Log in to see 71908 13
0.0010564557 ABIN238402 FACS PE Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1
0.0010564557 ABIN1106167 FACS PE Mouse IgG1 Log in to see B-K29 1
0.0010564557 ABIN238401 FACS Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1
0.0010564557 ABIN238400 FACS FITC Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1

Top referenced anti-TNFRSF10B antibody for Flow Cytometry

Similar anti-TNFRSF10B Antibodies

Application / Reactivity Human
ELISA 63 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 147 Antibodies
Functional Studies (Func) 10 Antibodies
Immunochromatography (IC) 14 Antibodies
Immunocytochemistry (ICC) 39 Antibodies
Immunofluorescence (IF) 16 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 40 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 29 Antibodies
Immunoprecipitation (IP) 20 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 175 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Reactivity Human
(322), (73), (20), (1), (1), (1)
Host Mouse
(181), (165), (11), (9), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10B antibody is conjugated to PE
(23), (21), (16), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(191), (165), (73), (44), (41), (34), (25), (23), (16), (14), (13), (5), (4), (3), (3), (1), (1)
Pubmed 9 references available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B Antibody (ABIN2663241) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone DJR2-4 (7-8)
Isotype IgG1 kappa

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B Antibody (ABIN2663241) Images back to top
Antigen
Alternative Name CD262 (TNFRSF10B Antibody Abstract)
Background DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
Pathways p53 Signaling, Apoptosis

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B Antibody (ABIN2663241) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B Antibody (ABIN2663241) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TNFRSF10B Antibody (ABIN2663241)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Background publications

Magnussen, Ree Rosnes, Shahzidi, Dong, Emilsen, Engesæter, Flørenes: "Synthetic retinoid CD437 induces apoptosis and acts synergistically with TRAIL receptor-2 agonist in malignant melanoma." in: Biochemical and biophysical research communications, Vol. 420, Issue 3, pp. 516-22, 2012

Canestraro, Galimberti, Savli, Palumbo, Tibullo, Nagy, Guerrini, Piaggi, Cine, Metelli, Petrini: "Synergistic antiproliferative effect of arsenic trioxide combined with bortezomib in HL60 cell line and primary blasts from patients affected by myeloproliferative disorders." in: Cancer genetics and cytogenetics, Vol. 199, Issue 2, pp. 110-20, 2010

Sato, Nakaoka, Yamashita, Yagita, Kawasaki, Morimoto, Baba, Matsuyama: "TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 7, pp. 4025-33, 2005

LaVallee, Zhan, Johnson, Herbstritt, Swartz, Williams, Hembrough, Green, Pribluda: "2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway." in: Cancer research, Vol. 63, Issue 2, pp. 468-75, 2003

Shigeno, Nakao, Ichikawa, Suzuki, Kawakami, Abiru, Miyazoe, Nakagawa, Ishikawa, Hamasaki, Nakata, Ishii, Eguchi: "Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation." in: Oncogene, Vol. 22, Issue 11, pp. 1653-62, 2003

Uno, Inukai, Kayagaki, Goi, Sato, Nemoto, Takahashi, Kagami, Yamaguchi, Yagita, Okumura, Koyama-Okazaki, Suzuki, Sugita, Nakazawa: "TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells." in: Blood, Vol. 101, Issue 9, pp. 3658-67, 2003

Nimmanapalli, Perkins, Orlando, OBryan, Nguyen, Bhalla et al.: "Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein ..." in: Cancer research, Vol. 61, Issue 2, pp. 759-63, 2001

MacFarlane, Ahmad, Srinivasula, Fernandes-Alnemri, Cohen, Alnemri: "Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL." in: The Journal of biological chemistry, Vol. 272, Issue 41, pp. 25417-20, 1997

Walczak, Degli-Esposti, Johnson, Smolak, Waugh, Boiani, Timour, Gerhart, Schooley, Smith, Goodwin, Rauch: "TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL." in: The EMBO journal, Vol. 16, Issue 17, pp. 5386-97, 1997

Images

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B Antibody (ABIN2663241) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b)  (PE) (ABIN2663241) anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibody (PE)