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anti-Human TNFRSF10B antibody for Flow Cytometry

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • cd262
  • CD262
  • dr5
  • DR5
  • killer
  • KILLER
  • KILLER/DR5
  • Ly98
  • MK
  • TNFRSF10B
  • TRAIL-R2
  • TRAILR2
  • trailr2
  • TRICK2
  • trick2
  • TRICK2A
  • trick2a
  • trick2b
  • TRICK2B
  • trickb
  • TRICKB
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • ZTNFR9
Reactivity
Human
257
61
19
1
1
1
Host
Mouse
169
111
10
7
2
2
Clonality
Monoclonal
Conjugate
This TNFRSF10B antibody is conjugated to APC
19
18
14
4
4
3
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
156
106
69
41
36
30
23
23
14
11
11
4
3
3
2
1
1
Supplier
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Catalog No. ABIN2658556
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3068567 ABIN2663241 FACS PE Mouse IgG1 kappa Log in to see DJR2-4 (7-8) 9
0.3068567 ABIN2664458 FACS Mouse IgG1 kappa Log in to see DJR2-2 (2-6) 9
0.3068567 ABIN2664459 FACS Mouse IgG1 kappa Log in to see DJR2-4 (7-8) 8
0.3068567 ABIN1996884 FACS PE Rabbit IgG AA 1-182 Log in to see 102
0.3068567 ABIN1996881 FACS ELISA Rabbit IgG AA 1-182 Log in to see 102
0.3068567 ABIN2678249 FACS PE Mouse IgG1 kappa Log in to see DJR2-4 (a-k-a-7-8)
0.0010666476 ABIN238402 FACS PE Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1
0.0010666476 ABIN1106167 FACS PE Mouse IgG1 Log in to see B-K29 1
0.0010666476 ABIN238400 FACS FITC Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1
0.0010666476 ABIN1106166 FACS Mouse IgG1 Log in to see B-K29 2
0.0010666476 ABIN238401 FACS Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1
0.0010666476 ABIN372450 FACS IF IHC (p) WB Rabbit IgG AA 388-407, Isoform 2 Log in to see Polyclonal
0.0010666476 ABIN1169245 Func ICC FACS IP Mouse IgG1 Log in to see HS201 6
0.0010666476 ABIN94304 FACS Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1
0.0010666476 ABIN342736 FACS IHC ELISA WB Goat Extracellular Domain Log in to see Polyclonal
0.0010666476 ABIN1169244 FACS IHC WB Mouse IgG1 Log in to see TR2-21
0.0010666476 ABIN1383913 FACS PE Mouse IgG1 Log in to see B-K29 1
0.0010666476 ABIN298144 FACS FITC Mouse IgG1 Extracellular Domain Log in to see DR5-01-1
0.0010666476 ABIN290834 ICC FACS IHC (p) WB Rabbit IgG AA 388-407 Log in to see Polyclonal
0.0010666476 ABIN192358 FACS FITC Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1

Top referenced anti-TNFRSF10B antibody for Flow Cytometry

Similar anti-TNFRSF10B Antibodies

Application / Reactivity Human
ELISA 59 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 96 Antibodies
Functional Studies (Func) 10 Antibodies
Immunochromatography (IC) 14 Antibodies
Immunocytochemistry (ICC) 36 Antibodies
Immunofluorescence (IF) 13 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies
Immunohistochemistry (IHC) 39 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antibodies
Immunoprecipitation (IP) 20 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 144 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Reactivity Human
(257), (61), (19), (1), (1), (1)
Host Mouse
(169), (111), (10), (7), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10B antibody is conjugated to APC
(19), (18), (14), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
(156), (106), (69), (41), (36), (30), (23), (23), (14), (11), (11), (4), (3), (3), (2), (1), (1)
Pubmed 8 references available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B Antibody (ABIN2658556) Images
Purification The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Clone DJR2-4 (7-8)
Isotype IgG1 kappa

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B Antibody (ABIN2658556) Images back to top
Antigen
Alternative Name CD262 (TNFRSF10B Antibody Abstract)
Background DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
Pathways p53 Signaling, Apoptosis

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B Antibody (ABIN2658556) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B Antibody (ABIN2658556) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TNFRSF10B Antibody (ABIN2658556)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Background publications

Lundqvist, Abrams, Schrump, Alvarez, Suffredini, Berg, Childs: "Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity." in: Cancer research, Vol. 66, Issue 14, pp. 7317-25, 2006

Sato, Nakaoka, Yamashita, Yagita, Kawasaki, Morimoto, Baba, Matsuyama: "TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 7, pp. 4025-33, 2005

LaVallee, Zhan, Johnson, Herbstritt, Swartz, Williams, Hembrough, Green, Pribluda: "2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway." in: Cancer research, Vol. 63, Issue 2, pp. 468-75, 2003

Shigeno, Nakao, Ichikawa, Suzuki, Kawakami, Abiru, Miyazoe, Nakagawa, Ishikawa, Hamasaki, Nakata, Ishii, Eguchi: "Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation." in: Oncogene, Vol. 22, Issue 11, pp. 1653-62, 2003

Uno, Inukai, Kayagaki, Goi, Sato, Nemoto, Takahashi, Kagami, Yamaguchi, Yagita, Okumura, Koyama-Okazaki, Suzuki, Sugita, Nakazawa: "TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells." in: Blood, Vol. 101, Issue 9, pp. 3658-67, 2003

Nimmanapalli, Perkins, Orlando, OBryan, Nguyen, Bhalla et al.: "Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein ..." in: Cancer research, Vol. 61, Issue 2, pp. 759-63, 2001

MacFarlane, Ahmad, Srinivasula, Fernandes-Alnemri, Cohen, Alnemri: "Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL." in: The Journal of biological chemistry, Vol. 272, Issue 41, pp. 25417-20, 1997

Walczak, Degli-Esposti, Johnson, Smolak, Waugh, Boiani, Timour, Gerhart, Schooley, Smith, Goodwin, Rauch: "TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL." in: The EMBO journal, Vol. 16, Issue 17, pp. 5386-97, 1997

Images

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B Antibody (ABIN2658556) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b)  (APC) (ABIN2658556) anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibody (APC)