anti-Human TNFRSF10B antibody for Immunocytochemistry

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b-b
  • tnfrsf10b
Reactivity
Human
324
76
26
1
1
1
1
1
Host
Mouse
181
168
10
6
6
2
Clonality
Monoclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
23
20
16
6
5
5
5
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)
195
162
73
51
38
32
27
25
15
13
12
4
4
4
3
3
2
1
Options
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Catalog No. ABIN1169245
$ 393.75
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN213934 ICC IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4361766 FACS ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 37
1 ABIN1030367 ICC ELISA WB Rabbit C-Term Log in to see Polyclonal 2
1 ABIN290834 ICC FACS IHC (p) WB Rabbit IgG AA 388-407 Log in to see Polyclonal
1 ABIN2470152 ICC FACS IHC WB Rabbit IgG AA 388-407 Log in to see Polyclonal
1 ABIN4903511 ICC WB Mouse IgG Log in to see
1 ABIN1733773 ICC FACS IHC (p) WB Rabbit IgG AA 388-407 Log in to see Polyclonal
1 ABIN1002207 ICC ELISA WB Rabbit IgG Log in to see Polyclonal 4
1 ABIN5542749 ICC WB Mouse IgG1 Log in to see 7F4-F8-G11
1 ABIN2964489 ICC FACS Atto 488 Mouse IgG1 Log in to see HS201
1 ABIN2964490 ICC FACS Atto 647N Mouse IgG1 Log in to see HS201
1 ABIN2964487 ICC FACS IP Neut Biotin Mouse IgG1 Log in to see HS201
1 ABIN2964488 ICC FACS FITC Mouse IgG1 Log in to see HS201
1 ABIN151173 ICC IF IHC (fro) WB Rabbit Log in to see Polyclonal
1 ABIN1733770 ICC IF IHC (p) WB Rabbit IgG AA 388-407 Log in to see Polyclonal
1 ABIN1169239 ICC FACS FITC Mouse IgG1 Log in to see HS201
1 ABIN1169242 FACS Func ICC IHC IP Biotin Mouse IgG1 Log in to see HS201
1 ABIN1169240 ICC FACS Atto 488 Mouse IgG1 Log in to see HS201
1 ABIN1169241 ICC FACS Atto 647N Mouse IgG1 Log in to see HS201
1 ABIN2964485 ICC FACS IP Neut Mouse IgG1 Log in to see HS201

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Reactivity Human
(324), (76), (26), (1), (1), (1), (1), (1)
Host Mouse
(181), (168), (10), (6), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10B antibody is un-conjugated
(23), (20), (16), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)
(195), (162), (73), (51), (38), (32), (27), (25), (15), (13), (12), (4), (4), (4), (3), (3), (2), (1)
Pubmed 6 references available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling ProductDetails: References for anti-TNFRSF10B antibody (ABIN1169245) Images
Specificity Recognizes human TRAIL-R2.
Cross-Reactivity Human
Cross-Reactivity (Details) Does not cross-react with human TRAIL-R1, -R3 or -R4.
Purification Purified from concentrated hybridoma tissue culture supernatant.
Purity >95 % (SDS-PAGE)
Immunogen Recombinant human TRAIL-R2 (DR5).
Clone HS201
Isotype IgG1

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling ProductDetails: References for anti-TNFRSF10B antibody (ABIN1169245) Images back to top
Antigen
Alternative Name TRAIL-R2 (TNFRSF10B Antibody Abstract)
Background TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling ProductDetails: References for anti-TNFRSF10B antibody (ABIN1169245) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details ProductDetails: References for anti-TNFRSF10B antibody (ABIN1169245) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months

ProductDetails: References for anti-TNFRSF10B antibody (ABIN1169245)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Product cited in:

Ganten, Haas, Sykora, Stahl, Sprick, Fas, Krueger, Weigand, Grosse-Wilde, Stremmel, Krammer, Walczak: "Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs." in: Cell death and differentiation, Vol. 11 Suppl 1, pp. S86-96, 2004

Jin, Kurakin, Benhaga, Abe, Mohseni, Sandra, Song, Kay, Khosravi-Far: "Fas-associated protein with death domain (FADD)-independent recruitment of c-FLIPL to death receptor 5." in: The Journal of biological chemistry, Vol. 279, Issue 53, pp. 55594-601, 2004

Washburn, Weigand, Grosse-Wilde, Janke, Stahl, Rieser, Sprick, Schirrmacher, Walczak: "TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 4, pp. 1814-21, 2003

Leverkus, Sprick, Wachter, Mengling, Baumann, Serfling, Bröcker, Goebeler, Neumann, Walczak: "Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation." in: Molecular and cellular biology, Vol. 23, Issue 3, pp. 777-90, 2003

Sprick, Rieser, Stahl, Grosse-Wilde, Weigand, Walczak: "Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8." in: The EMBO journal, Vol. 21, Issue 17, pp. 4520-30, 2002

Higuchi, Yoon, Grambihler, Werneburg, Bronk, Gores: "Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosis." in: The Journal of biological chemistry, Vol. 278, Issue 1, pp. 454-61, 2002