anti-Human TNFRSF10B antibody for Immunohistochemistry

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b-b
  • tnfrsf10b
Reactivity
Human
323
76
26
1
1
1
1
1
Host
Mouse
180
168
10
6
6
2
Clonality
Monoclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
23
20
16
6
5
5
5
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
194
162
73
51
39
32
27
26
15
13
13
4
4
3
3
2
2
1
Options
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Catalog No. ABIN1169244
$ 393.75
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.637035 ABIN2470152 ICC FACS IHC WB Rabbit IgG AA 388-407 Log in to see Polyclonal
9.637035 ABIN2404138 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN1169245 FACS Func ICC IHC IP Mouse IgG1 Log in to see HS201 6
1 ABIN4361766 FACS ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 37
1 ABIN342736 FACS IHC ELISA WB Goat Extracellular Domain Log in to see Polyclonal
1 ABIN4361781 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
1 ABIN791067 IHC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1875126 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN3021808 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN1169242 FACS Func ICC IHC IP Biotin Mouse IgG1 Log in to see HS201
1 ABIN2964491 FACS IHC WB Mouse IgG1 Log in to see TR2-21
1 ABIN1582783 IHC ELISA WB Rabbit Log in to see Polyclonal
1 ABIN4361767 FACS ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 18
1 ABIN1980532 ICC IHC IP WB Rabbit IgG AA 234-435 Log in to see Polyclonal
1 ABIN1820468 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2467226 IHC WB Rabbit IgG AA 380-398 Log in to see Polyclonal
1 ABIN2255639 IC FACS IHC ELISA WB Goat IgG Log in to see Polyclonal
1 ABIN2377514 IHC WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2255628 IC FACS IF IHC WB Rabbit IgG AA 388-407 Log in to see Polyclonal
1 ABIN4361788 IHC WB Mouse IgG1 Log in to see 2A5

Top referenced anti-TNFRSF10B antibody for Immunohistochemistry

  • Human Polyclonal TNFRSF10B Primary Antibody for FACS, ICC - ABIN4361766 (37 Publications): Basile, Zacny, Münger et al.: The cytokines tumor necrosis factor-alpha (TNF-alpha ) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the ... in The Journal of biological chemistry 2001 (PubMed)

  • Human Polyclonal TNFRSF10B Primary Antibody for FACS, ICC - ABIN4361767 (18 Publications): Cuello, Ettenberg, Clark, Keane, Posner, Nau, Dennis, Lipkowitz et al.: Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that ... in Cancer research 2001 (PubMed)

  • Human Monoclonal TNFRSF10B Primary Antibody for FACS, Func - ABIN1169245 (6 Publications): Sprick, Rieser, Stahl, Grosse-Wilde, Weigand, Walczak: Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. in The EMBO journal 2002 (PubMed)

  • Human Polyclonal TNFRSF10B Primary Antibody for IHC, IHC (p) - ABIN4361781 (1 Publications): Rivoltini, Chiodoni, Squarcina, Tortoreto, Villa, Vergani, Bürdek, Botti, Arioli, Cova, Mauri, Vergani, Bianchi, Della Mina, Cantone, Bollati, Zaffaroni, Gianni, Colombo, Huber: TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site. in Clinical cancer research : an official journal of the American Association for Cancer Research 2016 (PubMed)

Similar anti-TNFRSF10B Antibodies

Application / Reactivity Human
Cytometry by Time of Flight (CyTOF) 2 Antibodies
ELISA 61 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 147 Antibodies
Functional Studies (Func) 10 Antibodies
Immunochromatography (IC) 13 Antibodies
Immunocytochemistry (ICC) 37 Antibodies
Immunofluorescence (IF) 15 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 14 Antibodies
Immunohistochemistry (IHC) 44 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 29 Antibodies
Immunoprecipitation (IP) 21 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 174 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Reactivity Human
(323), (76), (26), (1), (1), (1), (1), (1)
Host Mouse
(180), (168), (10), (6), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10B antibody is un-conjugated
(23), (20), (16), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (IHC)
(194), (162), (73), (51), (39), (32), (27), (26), (15), (13), (13), (4), (4), (3), (3), (2), (2), (1)
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling Images
Specificity Recognizes human TRAIL-R2.
Cross-Reactivity Human
Cross-Reactivity (Details) Does not cross-react with human TRAIL-R1, -R3 or -R4.
Purification Purified from concentrated hybridoma tissue culture supernatant.
Purity >95 % (SDS-PAGE)
Immunogen Recombinant human TRAIL-R2 (DR5).
Clone TR2-21
Isotype IgG1

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling Images back to top
Antigen
Alternative Name TRAIL-R2 (TNFRSF10B Antibody Abstract)
Background TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Specially developed for the immunohistochemical detection of TRAIL-R2 in paraffin embedded tissue. Has been shown to detect TRAIL-R2 expressed at endogenous levels in paraffin-embedded tissue in different mammary carcinoma tissues.

Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months

Images

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b) (ABIN1169244) Negative control.
Immunohistochemistry (IHC) image for anti-TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b) (ABIN1169244) Immunohistochemistry detection of endogenous TRAIL-R2 in paraffin-embedded human carc...