Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
High TRIM29 expression is associated with metastasis of nasopharyngeal carcinoma.
Data show that TRIM29 promotes tumor progression by activating Wnt (show WNT2 ELISA Kits)/beta-Catenin (show CTNNB1 ELISA Kits) signaling.
This study establishes TRIM29 as a hypoxia-induced tumor suppressor gene and provides a novel molecular mechanism for ATM (show ATM ELISA Kits)-dependent breast cancer suppression.
Upregulation of TRIM29 is associated with thyroid cancer.
miR (show MLXIP ELISA Kits)-761 acts as an oncogene (show RAB1A ELISA Kits) in triple-negative breast cancer. This mode of action can, at least partially, be ascribed to the down-regulation of its target TRIM29.
Silencing of TRIM29 significantly inhibited the migration and invasion ability of CRC (show CALR ELISA Kits) cells.
Findings established a role for ATDC/TRIM29 as a robust pathogenic driver of bladder cancer development, identified downstream effector pathways, and implicated ATDC as a candidate biomarker and therapeutic target.
define a novel function for ATDC in the RNF8 (show RNF8 ELISA Kits)-mediated DNA damage response and implicate RNF8 (show RNF8 ELISA Kits) binding as a key determinant of the radioprotective function of ATDC
Results suggest that TRIM29 functions as an oncogene (show RAB1A ELISA Kits) in gastric cancer and is regulated by miR (show MLXIP ELISA Kits)-185.
TRIM29 functions as a scaffold protein (show HOMER1 ELISA Kits) to assemble DNA repair proteins into chromatin followed by efficient activation of DNA damage response.
this study shows that deletion of TRIM29 enhanced macrophage production of type I interferons and protected mice from infection with influenza virus, while challenge of Trim29-/- mice with Haemophilus influenzae resulted in lethal lung inflammation due to massive production of proinflammatory cytokines by macrophages
ATDC up-regulates CD44 (show CD44 ELISA Kits) in mouse and human PanIN lesions via activation of beta-catenin (show CTNNB1 ELISA Kits) signaling, leading to the induction of an epithelial-to-mesenchymal transition (EMT (show ITK ELISA Kits)) phenotype characterized by expression of Zeb1 (show ZEB1 ELISA Kits) and Snail1 (show SNAI1 ELISA Kits).
Histone deacetylase 9 (HDAC9 (show HDAC9 ELISA Kits)) regulates the functions of the ATDC (TRIM29) protein
ATDC increases cell proliferation via inhibition of p53 (show TP53 ELISA Kits) nuclear activities.
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
ataxia telangiectasia group D-associated protein
, ataxia-telangiectasia group D-associated protein
, tripartite motif protein TRIM29
, tripartite motif-containing 29
, tripartite motif-containing protein 29
, tripartite motif protein 29
, tripartite motif-containing protein 29-like