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anti-Human XPC antibody for ELISA

Recommended XPC Antibody (supplied by: Log in to see )

Antigen
Xeroderma Pigmentosum, Complementation Group C (XPC) Antibodies
  • RAD4
  • XP3
  • XPCC
Epitope
AA 141-251
19
17
13
6
5
2
2
2
1
1
Reactivity
Human
86
27
18
Host
Mouse
71
20
Clonality
Monoclonal
Conjugate
This XPC antibody is un-conjugated
7
7
6
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
66
27
25
20
18
16
11
3
2
2
Supplier
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Catalog No. ABIN396711
$ 450.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.32670403 ABIN563389 ELISA WB Mouse IgG2a kappa AA 141-250, partial Log in to see 6D11
0.001210097 ABIN1948984 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN1948985 ELISA WB FITC Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN1948986 ELISA WB Biotin Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN1948988 ELISA WB PE Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN1948987 ELISA WB APC Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN1583828 ELISA WB Rabbit C-Term Log in to see Polyclonal
0.001210097 ABIN1948989 ELISA WB HRP Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN563388 ELISA WB Mouse AA 141-250, partial Log in to see Polyclonal
0.001210097 ABIN2568930 ELISA Rabbit IgG AA 154-183 Log in to see Polyclonal
0.001210097 ABIN1829132 ELISA WB Mouse IgG2a, kappa Log in to see 6D11
0.001210097 ABIN2390763 ELISA WB PE Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN2390765 ELISA WB APC Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN2390768 ELISA WB HRP Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN2390767 ELISA WB FITC Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN2390769 ELISA WB Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN1105061 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.001210097 ABIN2390764 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN2390766 ELISA WB Biotin Rabbit IgG N-Term, AA 154-183 Log in to see Polyclonal
0.001210097 ABIN2390761 ELISA WB Mouse IgG2a kappa AA 141-251 Log in to see 6D11

Top referenced anti-XPC antibody for ELISA

  • Human Monoclonal XPC Primary Antibody for ELISA, WB - ABIN396711 (5 Publications): Palli, Polidoro, DErrico, Saieva, Guarrera, Calcagnile, Sera, Allione, Gemma, Zanna, Filomena, Testai, Caini, Moretti, Gomez-Miguel, Nesi, Luzzi, Ottini, Masala, Matullo, Dogliotti: Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer. in Mutagenesis 2010 (PubMed)

Similar anti-XPC Antibodies

Application / Reactivity Human
ELISA 25 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Immunocytochemistry (ICC) 16 Antibodies
Immunofluorescence (IF) 19 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 21 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 66 Antibodies

General

Antigen Xeroderma Pigmentosum, Complementation Group C (XPC) Antibodies
Epitope AA 141-251
(19), (17), (13), (6), (5), (2), (2), (2), (1), (1)
Reactivity Human
(86), (27), (18)
Host Mouse
(71), (20)
Clonality (Clone)
Monoclonal   ( )
Conjugate This XPC antibody is un-conjugated
(7), (7), (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(66), (27), (25), (20), (18), (16), (11), (3), (2), (2)
Pubmed 5 references available
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Product Details anti-XPC Antibody

Target Details XPC Application Details Handling References for anti-XPC Antibody (ABIN396711) Images
Specificity XPC (NP_004619, 141 a.a. ~ 251 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen XPC (NP_004619, 141 a.a. ~ 251 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6D11
Isotype IgG2a kappa

Target Details XPC

Product Details anti-XPC Antibody Application Details Handling References for anti-XPC Antibody (ABIN396711) Images back to top
Antigen
Alternative Name XPC (XPC Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 105981 DA
Gene ID 12406
NCBI Accession NP_004619
Research Area Cell Structure
Pathways p53 Signaling, DNA Damage Repair

Application Details

Product Details anti-XPC Antibody Target Details XPC Handling References for anti-XPC Antibody (ABIN396711) Images back to top
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Restrictions For Research Use only

Handling

Product Details anti-XPC Antibody Target Details XPC Application Details References for anti-XPC Antibody (ABIN396711) Images back to top
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months

References for anti-XPC Antibody (ABIN396711)

Product Details anti-XPC Antibody Target Details XPC Application Details Handling Images back to top
Background publications

Palli, Polidoro, DErrico, Saieva, Guarrera, Calcagnile, Sera, Allione, Gemma, Zanna, Filomena, Testai, Caini, Moretti, Gomez-Miguel, Nesi, Luzzi, Ottini, Masala, Matullo, Dogliotti: "Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer." in: Mutagenesis, Vol. 25, Issue 6, pp. 569-75, 2010

Long, Ma, Zhou, Ma, Fu: "Polymorphism in xeroderma pigmentosum complementation group C codon 939 and aflatoxin B1-related hepatocellular carcinoma in the Guangxi population." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1301-9, 2010

Figl, Scherer, Nagore, Bermejo, Botella-Estrada, Gast, Thirumaran, Planelles, Hemminki, Schadendorf, Kumar: "Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma." in: Mutation research, Vol. 702, Issue 1, pp. 8-16, 2010

Guillem, Cervantes, Martínez, Alvarez-Larrán, Collado, Camós, Sureda, Maffioli, Marugán, Hernández-Boluda: "XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia." in: American journal of hematology, Vol. 85, Issue 7, pp. 482-6, 2010

Zhu, Xu, Hong, Yue, Zhang, Ye, Yuan: "XPC gene intron 11 C/A polymorphism is a predictive biomarker for the sensitivity to NP chemotherapy in patients with non-small cell lung cancer." in: Anti-cancer drugs, Vol. 21, Issue 7, pp. 669-73, 2010

Images

Product Details anti-XPC Antibody Target Details XPC Application Details Handling References for anti-XPC Antibody (ABIN396711) back to top
Supplier Images
ELISA image for anti-XPC antibody (Xeroderma Pigmentosum, Complementation Group C) (AA 141-251) (ABIN396711) Detection limit for recombinant GST tagged XPC is approximately 0.03 ng/mL as a captu...