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anti-Human XPC antibody for Immunohistochemistry (Frozen Sections)

Recommended XPC Antibody (supplied by: Log in to see )

Antigen
Xeroderma Pigmentosum, Complementation Group C (XPC) Antibodies
  • RAD4
  • XP3
  • XPCC
Epitope
C-Term
19
17
13
5
5
2
2
2
2
1
Reactivity
Human
87
28
18
Host
Rabbit
70
22
Clonality
Polyclonal
Conjugate
This XPC antibody is un-conjugated
7
7
6
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
67
28
26
21
19
17
11
3
1
1
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Catalog No. ABIN1109520
$ 555.50
Plus shipping costs $45.00

Similar anti-XPC Antibodies

Application / Reactivity Human
ELISA 25 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Immunocytochemistry (ICC) 16 Antibodies
Immunofluorescence (IF) 19 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 21 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 66 Antibodies

General

Antigen Xeroderma Pigmentosum, Complementation Group C (XPC) Antibodies
Epitope C-Term
(19), (17), (13), (5), (5), (2), (2), (2), (2), (1)
Reactivity Human
(87), (28), (18)
Host Rabbit
(70), (22)
Clonality
Polyclonal
Conjugate This XPC antibody is un-conjugated
(7), (7), (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(67), (28), (26), (21), (19), (17), (11), (3), (1), (1)
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Product Details anti-XPC Antibody

Target Details XPC Application Details Handling Images
Specificity Reacts with Human 105 kDa XPC protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity Chromatography on Protein A
Immunogen Synthetic peptide derived from C-terminal domain of Human XPC protein

Target Details XPC

Product Details anti-XPC Antibody Application Details Handling Images back to top
Antigen
Alternative Name XPC / XPCC (XPC Antibody Abstract)
Background Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair. XPC may play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C (XPC), also known as xeroderma pigmentosum III (XP3). XPC is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities.Synonyms: DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125
Gene ID 7508
NCBI Accession NP_001139241
Pathways p53 Signaling, DNA Damage Repair

Application Details

Product Details anti-XPC Antibody Target Details XPC Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-XPC Antibody Target Details XPC Application Details Images back to top
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer