CD3 FITC - CD16&56 PE Bi-Test Reagent

Details for Product No. ABIN2763682, Supplier: Log in to see
Antigen
Reactivity
Human
Host
Mouse
Clonality (Clone)
Monoclonal ()
Conjugate
FITC,PE
Application
Flow Cytometry (FACS)
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Brand Bi-Test™
Clone M2AB-J5511-C5-9
Isotype IgG1, IgG2b
Purification Protein A/G Chromatography
Background The CD3 epitope is expressed on the epsilon chain of the CD3/T cell antigen receptor (TcR) complex. CD3 is present on 65-85 % of thymocytes and has a mitogenic effect on peripheral blood T cells. Identification of human T cells expressing the 22-28,000 M.W. surface antigen. CD16 identifies human NK cell antigen expressing the 50 - 70 kDa M.W. surface antigen associated with the IgG Fc receptor III on NK cells and Neutrophils. CD16 is expressed on approximately 15 % of peripheral blood lymphocytes and is present on all resting NK cells. CD16 may be expressed on CD3 T cells from certain individuals. CD56, M.W.150,000 is expressed on approximately 10-25 % of human peripheral blood lymphocytes. CD56 (NKH-1) is expressed on human peripheral blood natural killer cells, representing a pan NK-cell antigen. Expressed on non-MHC-restricted cytotoxic T cells.
Restrictions For Research Use only
Storage 4 °C