Browse our anti-Cathepsin D (CTSD) Antibodies

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anti-Cathepsin D Antibodies (CTSD)
On are 333 Cathepsin D (CTSD) Antibodies from 38 different suppliers available. Additionally we are shipping Cathepsin D Kits (82) and Cathepsin D Proteins (67) and many more products for this protein. A total of 499 Cathepsin D products are currently listed.
CatD, Cathd, CD, CLN10, CPSD, CTSD, DDBDRAFT_0205785, DDBDRAFT_0215012, DDB_0205785, DDB_0215012, DKFZp469J0315, fb93e11, fj17b09, LOC398557, LOC100136761, wu:fb93e11, wu:fj17b09
list all antibodies Gene Name GeneID UniProt
CTSD 1509 P07339
CTSD 13033 P18242
CTSD 171293  

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anti-Human Cathepsin D Antibodies:

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anti-Rat (Rattus) Cathepsin D Antibodies:

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Top referenced anti-Cathepsin D Antibodies

  1. Human Monoclonal Cathepsin D Primary Antibody for IF, IP - ABIN968183 : Erickson, Conner, Blobel: Biosynthesis of a lysosomal enzyme. Partial structure of two transient and functionally distinct NH2-terminal sequences in cathepsin D. in The Journal of biological chemistry 1981 (PubMed)
    Show all 4 references for 968183

  2. Human Monoclonal Cathepsin D Primary Antibody for ELISA, EM - ABIN269482 : Kitamura, Nakamura, Miyamoto, Miyamoto, Kabu, Yoshida, Futamura, Ichinose, Arakawa: Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria. in PLoS ONE 2011 (PubMed)
    Show all 4 references for 269482

  3. Human Polyclonal Cathepsin D Primary Antibody for EIA, WB - ABIN951064 : Albayrak, Tirniceriu, Riemenschneider, Kurz, Scherag, Egensperger: The cathepsin D (224C/T) polymorphism confers an increased risk to develop Alzheimer's disease in men. in The journals of gerontology. Series A, Biological sciences and medical sciences 2010 (PubMed)
    Show all 3 references for 951064

  4. Human Monoclonal Cathepsin D Primary Antibody for EIA, IHC (p) - ABIN317502 : Fusek, Vetvicka: Dual role of cathepsin D: ligand and protease. in Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005 (PubMed)
    Show all 2 references for 317502

  5. Human Polyclonal Cathepsin D Primary Antibody for IHC (fro), IHC (p) - ABIN115287 : Henry, McCarthy, Angus, Westley, May, Nicholson, Cairns, Harris, Horne: Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study. in Cancer 1990 (PubMed)
    Show all 2 references for 115287

  6. Human Monoclonal Cathepsin D Primary Antibody for ELISA, EM - ABIN316063 : Miyamoto, Kitamura, Nakamura, Futamura, Miyamoto, Yoshida, Ono, Ichinose, Arakawa: Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control. in PLoS ONE 2011 (PubMed)
    Show all 2 references for 316063

  7. Human Polyclonal Cathepsin D Primary Antibody for ELISA, IF (cc) - ABIN732098 : Liao, Li, Li, Liu: Organellar proteome analyses of ricin toxin-treated HeLa cells. in Toxicology and industrial health 2014 (PubMed)

  8. Cow (Bovine) Polyclonal Cathepsin D Primary Antibody for WB - ABIN2776841 : Gambarte Tudela, Capmany, Romao, Quintero, Miserey-Lenkei, Raposo, Goud, Damiani: The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions. in Journal of cell science 2015 (PubMed)

More Antibodies against Cathepsin D Interaction Partners

Zebrafish Cathepsin D (CTSD) interaction partners

Silk Worm Cathepsin D (CTSD) interaction partners

  1. These results suggest that the ecdysone response elements are vital for activation of the promoter by 20-hydroxyecdysone (20E) in the larval fat body and further support the crucial role of ecdysone signaling to control cathepsin D gene transcription.

Human Cathepsin D (CTSD) interaction partners

  1. Secreted PGRN (show GRN Antibodies) is incorporated into cells via sortilin (show SORT1 Antibodies) or cation-independent mannose 6-phosphate receptor (show IGF2R Antibodies), and facilitated the acidification of lysosomes and degradation of CTSDmat. Moreover, the change of PGRN (show GRN Antibodies) levels led to a cell-type-specific increase of insoluble TDP-43 (show TARDBP Antibodies). In the brain tissue of FTLD-TDP patients with PGRN (show GRN Antibodies) deficiency, CTSD and phosphorylated TDP-43 (show TARDBP Antibodies) accumulated in neurons

  2. CTSD, in need of its catalytic activity, may promote proliferation in advanced glycation end products-treated human umbilical vein endothelial cells independent of the autophagy-lysosome pathway.

  3. Cathepsin D facilitates the TRAIL-induced apoptosis of MDA-MB-231 breast cancer cells in enzymatic activity-dependent manner. Caspase-8 (show CASP8 Antibodies) and Bid (show BID Antibodies) proteins are the CD targets. The modulatory role of CD in cell response to TRAIL was also confirmed in another breast cancer cell line SKBR3.

  4. Gene expression level of CTSD is significantly higher in AD patients when compared to normal controls.

  5. There was a significant difference between groups with and without endothelial dysfunction in terms of cathepsin D levels, and negative and significant correlations were found between brachial artery FMD (show FLNA Antibodies)% and cathepsin D levels. Cathepsin D, which is known to be associated with atherosclerosis, may play a role in the proce

  6. Serum CTSB (show CTSB Antibodies) and CTSD concentrations were found to have a diagnostic value in NPC (show NPC1 Antibodies). However, the CTSB (show CTSB Antibodies) and CTSD serum levels had no prognostic role for the outcome in nasopharyngeal carcinoma patients.

  7. Fibroblasts from Niemann-Pick type C (NPC (show NPC1 Antibodies)) disease patients with low levels of NPC1 (show NPC1 Antibodies) protein have high amounts of procathepsin D but reduced quantities of the mature protein, thus showing a diminished cathepsin D activity.

  8. Data indicate that cathepsin D (CD) protein is elevated in the retinas of diabetic mice and serum of human patients with diabetic macular edema (DME).

  9. Data show that co-silencing of tricho-rhino-phalangeal-syndrome (TRPS1 (show TRPS1 Antibodies)) and cathepsin D (Cath-D) in breast cancer cells (BCC) affects the transcription of cell cycle and proliferation.

  10. Transcellular transmission of alpha-synuclein (show SNCA Antibodies) aggregates is increased in CTSD mutated cells.

Mouse (Murine) Cathepsin D (CTSD) interaction partners

  1. Exposure of J774A.1 cells to HOCl or HOSCN resulted in a significant decrease in the activity of the Cys (show DNAJC5 Antibodies)-dependent cathepsins B and L, but not the Asp (show C3 Antibodies)-dependent cathepsin D.

  2. these results suggest that inhibition of lysosomal proteases, such as CtsD, could be a new therapeutic approach to reduce renal fibrosis and slow progression of chronic kidney disease.

  3. The neuroectoderm specific cathepsin D (Ctsd) knock-out mice survived about 5.5 days longer.

  4. Data indicate that cathepsin D (CD) protein is elevated in the retinas of diabetic mice and serum of human patients with diabetic macular edema (DME).

  5. This study demonistrated that Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression.

  6. Post-translational modifications drive CatD into the nucleus to cleave Histone 3 in the involuting mammary gland.

  7. Increased lysosomal storage in CatD KO mice causes oxidative damage in brain pericytes, subsequently resulting in an increased vessel diameter and enhanced permeability of the BBB (show ALMS1 Antibodies).

  8. Mouse prolactin (show PRL Antibodies) was proteolytically cleaved by Cath D between amino acids 148 and 149. N-terminal prolactin (show PRL Antibodies) fragment and Cath D expression increased during mammary gland involution.

  9. Cathepsin D was not inherent to sperm themselves, but rather of epididymal origin and was presumably transported to the sperm surface via epididymosomes.

  10. TGase 2 (show TGM2 Antibodies) may regulate the balance between cell survival and cell death through the modulation of CTSD levels.

Cow (Bovine) Cathepsin D (CTSD) interaction partners

  1. Association of polymorphisms in calpain 1 (show CAPN1 Antibodies), (mu/I) large subunit, calpastatin (show CAST Antibodies), and cathepsin D genes with meat quality traits in double-muscled Piemontese cattle.

  2. findings strongly suggest a link between the lysosomal dysfunction of cathepsin D and the etiology of Alzheimer's disease

Pig (Porcine) Cathepsin D (CTSD) interaction partners

Rabbit Cathepsin D (CTSD) interaction partners

  1. The effect of heavy metal cations on the activity of cathepsin D, was studied.

Cathepsin D (CTSD) Antigen Profile

Antigen Summary

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Alternative names and synonyms associated with Cathepsin D (CTSD)

  • cathepsin D (ctsd) antibody
  • cathepsin D (LOC398557) antibody
  • cathepsin D (Cathd) antibody
  • cathepsin d (AaeL_AAEL006169) antibody
  • cathepsin D (LOC100136761) antibody
  • cathepsin D (CTSD) antibody
  • cathepsin D (ctsD) antibody
  • cathepsin D (catd) antibody
  • cathepsin D (Ctsd) antibody
  • cathepsin D (LOC100101595) antibody
  • CatD antibody
  • Cathd antibody
  • CD antibody
  • CLN10 antibody
  • CPSD antibody
  • CTSD antibody
  • DDBDRAFT_0205785 antibody
  • DDBDRAFT_0215012 antibody
  • DDB_0205785 antibody
  • DDB_0215012 antibody
  • DKFZp469J0315 antibody
  • fb93e11 antibody
  • fj17b09 antibody
  • LOC398557 antibody
  • LOC100136761 antibody
  • wu:fb93e11 antibody
  • wu:fj17b09 antibody

Protein level used designations for anti-Cathepsin D (CTSD) Antibodies

etID16901.18 , cathepsin D , aspartic protease , cathepsin d , preprocathepsin D , ceroid-lipofuscinosis, neuronal 10 , lysosomal aspartyl peptidase , lysosomal aspartyl protease , cathepsin D (lysosomal aspartyl peptidase) , cathepsin D (lysosomal aspartyl protease) , prepro-cathepsin D, prepro-CD

65225 Danio rerio
398557 Xenopus laevis
443721 Xenopus laevis
692768 Bombyx mori
5567565 Aedes aegypti
100136761 Oncorhynchus mykiss
100137367 Papio anubis
100168373 Acyrthosiphon pisum
100172401 Pongo abelii
8622052 Dictyostelium discoideum AX4
100528208 Ictalurus punctatus
1509 Homo sapiens
101094625 Felis catus
13033 Mus musculus
171293 Rattus norvegicus
282883 Bos taurus
483662 Canis lupus familiaris
494568 Sus scrofa
100101595 Oryctolagus cuniculus
100735735 Cavia porcellus
396090 Gallus gallus
443060 Ovis aries
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