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Browse our CDX2 Proteins (CDX2)

Full name:
Caudal Type Homeobox 2 Proteins (CDX2)
On are 5 Caudal Type Homeobox 2 (CDX2) Proteins from 4 different suppliers available. Additionally we are shipping CDX2 Antibodies (240) and CDX2 Kits (28) and many more products for this protein. A total of 286 CDX2 products are currently listed.
Cdx-2, CDX-3, CDX2, CDX3, cdx3-like, MGC130987
list all proteins Gene Name GeneID UniProt
CDX2 66019  
CDX2 1045 Q99626
CDX2 12591 P43241

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CDX2 Proteins (CDX2) by Origin

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More Proteins for CDX2 Interaction Partners

Rhesus Monkey Caudal Type Homeobox 2 (CDX2) interaction partners

  1. These results provide evidence that CDX2 plays an essential role in functional trophectoderm formation during primate embryonic development.

Human Caudal Type Homeobox 2 (CDX2) interaction partners

  1. we found that the loss of CDX2 expression in colorectal cancer is inversely related with the methylation of CDX2 promoter. The methylation of the CDX2 promoter was associated with enhanced lymph node metastases and shorter survival time ( p = 0.0273), but was independent of tumor stage, tumor differentiation, gender, and age.

  2. PAX2 (show PAX2 Proteins), PAX8 (show PAX8 Proteins), CDX2 immunostains was preformed to the TMA slides.

  3. In stomach adenocarcinomas, CDH17 positively stained 64.0% (112 of 175) of tissues, compared to CK20 (show KRT20 Proteins) and CDX2, where staining was observed in only 24.6% (43 of 175) and 46.9% (82 of 175), respectively.

  4. CDX2 expression correlates with gastric and intestinal differentiation in Barrett's esophagus towards adenocarcinoma.

  5. CDX2 inhibited pancreatic adenocarcinoma cell proliferation via promoting tumor suppressor miR (show MLXIP Proteins)-615-5p. Our findings suggested a potential molecular target for pancreatic adenocarcinoma therapy.

  6. Suggest that NKX6.3 (show NKX6-3 Proteins) might function as a master regulator of gastric differentiation by affecting SOX2 (show SOX2 Proteins) and CDX2 expression and the NKX6.3 (show NKX6-3 Proteins) inactivation may result in intestinal metaplasia in gastric epithelial cells.

  7. Immunohistochemical panel of CDX2, p120ctn, c-Myc, and Jagged1 proteins would be to distinguish between low/high grade dysplasia in histologically challenging cases of Barrett's esophagus.

  8. CDX2 single-nucleotide polymorphism is associated with cancer risk.

  9. CK7 (show KRT7 Proteins), TTF-1 (show NKX2-1 Proteins) and napsin A (show NAPSA Proteins) are predominantly expressed in primary lung adenocarcinoma patients, with CDX-2 being inconsistently expressed.

  10. Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (show HOXB7 Proteins) and Cdx2 in colon cancer cells.

Pig (Porcine) Caudal Type Homeobox 2 (CDX2) interaction partners

  1. showed novel molecular regulation of CDX2 on Oct4 (show POU5F1 Proteins), and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 (show POU5F1 Proteins) in embryo of mammals other than mouse

Mouse (Murine) Caudal Type Homeobox 2 (CDX2) interaction partners

  1. The authors identify a Cdx2-responsive segment of HoxA, immediately 5' to the recently defined regulatory domain orchestrating initial transcription of the first Hox (show MSH2 Proteins) gene.

  2. Cdx1 (show CDX1 Proteins)-Cdx2 double null mutants exhibited loss of primitive erythroblasts, aberrant vascular remodelling of the yolk sac (show ADCY10 Proteins) and a block in hematopoietic differentiation from yolk sac (show ADCY10 Proteins)-derived cells in culture.

  3. this study shows that Aloe vera (show IGF2BP3 Proteins) gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer

  4. Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (show HOXB7 Proteins) and Cdx2 in colon cancer cells.

  5. CDX2 is required for proliferation and differentiation of intestinal stem cells. Direct CDX2 targets in ISCs (show NFS1 Proteins) may be activated or repressed.

  6. cells in preimplantation embryos that localized in an initial outer position initiated the expression of Cdx2. cells that changed their position from an outer to an inner position downregulated Cdx2 expression and contributed to the inner cell mass.

  7. findings illuminated a role for NOD1 (show NOD1 Proteins) signaling in attenuating H. pylori-induced Cdx2 expression in gastric epithelial cells

  8. Overexpression of CDX2 inhibits the growth of the gastric cancer cells in vivo and in vitro.

  9. Intestinal stem cells transform into gastric stem cells on loss of transcription factor Cdx2.

  10. GATA4 (show GATA4 Proteins) and HNF4A (show HNF4A Proteins) control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2

Cow (Bovine) Caudal Type Homeobox 2 (CDX2) interaction partners

  1. results thus indicate that CDX2 is not required for TE formation during bovine development; nevertheless, it is necessary for maintaining TE integrity.

CDX2 Protein Profile

Protein Summary

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.

Alternative names and synonyms associated with CDX2

  • caudal type homeobox 2 (CDX2)
  • caudal type homeobox 2 (cdx2)
  • caudal type homeo box 2 (Cdx2)
  • caudal type homeobox 2 (Cdx2)
  • Cdx-2 protein
  • CDX-3 protein
  • CDX2 protein
  • CDX3 protein
  • cdx3-like protein
  • MGC130987 protein

Protein level used designations for Caudal Type Homeobox 2 Proteins (CDX2)

caudal type homeobox 2 , caudal type homeobox transcription factor 2 , caudal type homeo box transcription factor 2 , homeobox protein CDX-2 , caudal-type homeobox protein 2 , caudal type homeo box 2 , caudal-type homeobox transcription factor 2

467350 Pan troglodytes
711094 Macaca mulatta
735025 Xenopus laevis
66019 Rattus norvegicus
1045 Homo sapiens
374205 Gallus gallus
486028 Canis lupus familiaris
100127132 Sus scrofa
12591 Mus musculus
618679 Bos taurus
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