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anti-Mouse (Murine) Inhibin alpha Antibodies:
anti-Rat (Rattus) Inhibin alpha Antibodies:
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Human Monoclonal Inhibin alpha Primary Antibody for IHC, ELISA - ABIN966402
Mayo, Cerelli, Spiess, Rivier, Rosenfeld, Evans, Vale: Inhibin A-subunit cDNAs from porcine ovary and human placenta. in Proceedings of the National Academy of Sciences of the United States of America 1986
Show all 4 Pubmed References
Human Monoclonal Inhibin alpha Primary Antibody for ICC, ELISA - ABIN969217
Palmieri, Wilson, Iversen, Clyde, Calingaert, Moorman, Poole, Anderson, Anderson, Anton-Culver, Beesley, Hogdall, Brewster, Carney, Chen, Chenevix-Trench, Chang-Claude, Cunningham, Dicioccio, Doherty et al.: Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. ... in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008
Show all 3 Pubmed References
Human Monoclonal Inhibin alpha Primary Antibody for ELISA, ICC - ABIN265618
Chauhan, Singh, Rai, Rai, Rai: Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation. in Journal of clinical immunology 2013
Human Polyclonal Inhibin alpha Primary Antibody for IHC (p), ELISA - ABIN2475098
Kuhn, Ayhan, Shih, Seidman, Kurman: Ovarian Brenner tumour: a morphologic and immunohistochemical analysis suggesting an origin from fallopian tube epithelium. in European journal of cancer (Oxford, England : 1990) 2013
Cow (Bovine) Polyclonal Inhibin alpha Primary Antibody for ELISA, WB - ABIN4226780
Nistal, Pastrián, González-Peramato, De Miguel: Inhibin bodies: a new marker for immature Sertoli cells. in Histopathology 2011
The stimulation of inha expression by FSH and the potential inhibition of FSH by inhibin suggest a possible existence of a negative feedback loop between the pituitary and ovary in the zebrafish.
findings report the changes in inhibin-alpha subunit gene expression in the corpus luteum is regulated by LH; results suggest a possible multiple crosstalk of Wnt, cAMP, and SF-1 in the regulation of luteal inhibin secretion
molecular cloning of a novel inhibin alpha cDNA
This study tested the hypothesis that inhibins act in an autocrine manner on Leydig cells using a pre-pubertal Leydig cell line, TM3 (show TPM1 Antibodies), as a model of immature Leydig cells.
The study is the first to identify an intratesticular role for inhibin/inhibin-alpha subunit, demonstrating that a threshold level of this protein is required for normal testis development and to sustain adult somatic testicular cell function.
inhibin is a broad regulatory marker in anterior pituitary cells
A novel role for GDF9 (show GDF9 Antibodies) in causing reproductive defects and suppressing tumor initiation in the Inha(-/-) mouse model.
Data indicate that the inhibin-alpha promoter is activated synergistically by Wt1 (show WT1 Antibodies) and Sf1 (show SF1 Antibodies).
Inhibin alpha-subunit N terminus interacts with activin type IB receptor (show ACVR1B Antibodies) to disrupt activin (show Actbeta Antibodies) signaling.
relationship between inhibin and Sertoli cell activity
These data support the role of proconvertase PCSK5 in the processing of ovarian inhibin subunits during folliculogenesis.
There are widespread alterations in the transcriptome of gonadotropin-treated Inha-/- granulosa cells, with significant changes in genes involved in extracellular matrix and cell-cell communication.
Results demonstrate that RB is not essential for Sertoli cell tumorigenesis in Inha KO mice but that loss of Inha accelerates the infertility phenotype of Rb cKO mice.
Inhibin-alpha gene is transcriptionally silenced in human leukemia cells. In addition, mutations in, and expression levels of, the inhibin-alpha gene differed between human lymphoid and myeloid leukemia (show BCL11A Antibodies) cells.
Results suggest that high expression levels of alpha-inhibin and beta-glycan transcripts in secretory phase endometrium are associated with a lower chance of achieving pregnancy with in vitro fertilization.
Anti-Mullerian hormone (AMH (show AMH Antibodies)) and inhibin-A (INH-A) levels were found to be significantly higher in the polycystic ovary syndrome (PCOS) group compared to the controls.
Immunostaining allowed the identification of specific cell types with E-cadherin (show CDH1 Antibodies), p53 (show TP53 Antibodies), and inhibin-alpha expression in all cases.
Each follicular fluid (FF) was individually aspirated and FF/serum EG-VEGF (show Prok1 Antibodies), inhibin-a, and FF IGF-1 (show IGF1 Antibodies) levels were evaluated. The pregnant group was characterized by increased numbers of WVFs (p = 0.044), a WVE (p = 0.022), and increased levels of FF IGF-1 (show IGF1 Antibodies) (p = 0.001) and serum EG-VEGF (show Prok1 Antibodies) (p = 0.03).
The Sertoli cell hormones inhibin-B and anti Mullerian hormone (show AMH Antibodies) have different patterns of secretion in prepubertal cryptorchid boys.
Aberrant methylation and common genetic variation in the INHA promoter occur in human adrenocortical carcinoma and are associated with decreased INHA expression.
the correlation between placental DNAm of INHBA (show INHBA Antibodies)/FN1 (show FN1 Antibodies) and maternal serum INHA/FN1 (show FN1 Antibodies) levels indicate that DNAm may be a useful tool to identify novel biomarkers for adverse pregnancy outcomes in some cases.
The present study did not find an association between INHA-124A>G and -16C>T and the risk of premature ovarian failure (POF (show POF1B Antibodies)). For the 769G>A mutation, Asian women with the 769A allele were found to be susceptible to POF (show POF1B Antibodies).
Inhibin alpha-subunit, Melan A (show MLANA Antibodies) and MNF116 were not sensitive for pheochromocytomas.
Data suggest that, in granulosa cells, inhibin alpha-subunit is involved in regulation of cell proliferation, extracellular matrix remodeling, oogenesis, and ovulation. These studies were conducted in China and involved transcriptome sequencing analysis in cultured granulosa cells (from slaughterhouse pigs) exposed in vitro to a neutralizing anti-inhibin alpha-subunit antibody.
The relationship of INHA insertion/deletion polymorphisms with follicular cysts was investigated
This study provides evidence that the expressions of inhibin alpha subunit and betaglycan (show TGFBR3 Antibodies) are inferior in cystic follicles, and this may be caused by the decrease in FSH (show BRD2 Antibodies) in the presence of a cystic follicle.
The c.-42G>A and c.3222G>A polymorphisms in the INHA gene are significantly associated with follicular cysts in sows.
INHA and INHB expression and cellular localization in porcine oocytes were studied.
Association of the INHA gene to ovulation rate.
inhibin alpha-subunits were localized in the granulosa cells of follicles at all stages but were not localized in corpora lutea.
The effects of castration and other surgical intervention on the blood levels of anti-Muellerian hormone (show AMH Antibodies), inhibin A, gonadotropins, and gonadotropin receptors in bull calves are reported.
The expression of the components of the activin (show Actbeta Antibodies)-inhibin-follistatin (show FST Antibodies) system is altered in bovine cystic ovarian disease.
INHA gene can be used as a predictor for superovulation in Chinese Holstein cows.
Inhibin has a negative autocrine or paracrine effect on the in vitro capacity of granulosa cells isolated from dominant or subordinate follicles to produce estradiol.
overexpression of inhibin alpha (1-32) fragment regulated granulosa cell development and effects on subsequent oocyte maturation were both time- and stage-dependent
The result showed that AA genotype had remarkable litter size at P1 locus in the three goat breeds (P < 0.05). Therefore, these results suggest that INHA gene is a strong candidate gene that affects litter size in goats.
Sequence comparison showed that three base changes in INHA(two amino acid substitutions), and three base changes in INHBA (show INHBA Antibodies),(one amino acid substitution). No difference seen in INHA or INHBA (show INHBA Antibodies) mRNA expression level in the follicle of the two goat breeds.
This gene encodes the alpha subunit of inhibins A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion.
inhibin alpha chain
, inhibin alpha subunit
, inhibin alpha subunit variant 1
, inhibin, alpha
, A-inhibin subunit
, inhibin alpha-subunit
, inhibin A
, inhibin precursor alpha subunit
, Inhibin alpha chain