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Browse our anti-RAB27A (RAB27A) Antibodies

Full name:
anti-RAB27A, Member RAS Oncogene Family Antibodies (RAB27A)
On www.antibodies-online.com are 83 RAB27A, Member RAS Oncogene Family (RAB27A) Antibodies from 20 different suppliers available. Additionally we are shipping RAB27A Proteins (16) and RAB27A Kits (1) and many more products for this protein. A total of 103 RAB27A products are currently listed.
Synonyms:
2210402C08Rik, 2410003M20Rik, 4933437C11Rik, ash, GS2, HsT18676, MGC80943, MGC89827, RAB27, RAB27A, RAM, zgc:114135
list all antibodies Gene Name GeneID UniProt
RAB27A 5873 P51159
RAB27A 11891 Q9ERI2
RAB27A 50645 P23640

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Most Popular Reactivities for anti-RAB27A (RAB27A) Antibodies

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anti-Human RAB27A Antibodies:

anti-Mouse (Murine) RAB27A Antibodies:

anti-Rat (Rattus) RAB27A Antibodies:

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Top referenced anti-RAB27A Antibodies

  1. Human Monoclonal RAB27A Primary Antibody for IHC (p), RNAi - ABIN562560 : Kimura, Kaneko, Yamada, Ishihara, Senda, Iwamatsu, Niki: The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines. in Journal of cell science 2008 (PubMed)
    Show all 7 references for ABIN562560

  2. Human Polyclonal RAB27A Primary Antibody for WB - ABIN1881720 : Ohbayashi, Mamishi, Ishibashi, Maruta, Pourakbari, Tamizifar, Mohammadpour, Fukuda, Parvaneh: Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2. in Pigment cell & melanoma research 2010 (PubMed)
    Show all 5 references for ABIN1881720

  3. Human Monoclonal RAB27A Primary Antibody for WB - ABIN396260 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
    Show all 5 references for ABIN396260

  4. Human Monoclonal RAB27A Primary Antibody for WB - ABIN967619 : Hong: Cytotoxic T lymphocyte exocytosis: bring on the SNAREs! in Trends in cell biology 2005 (PubMed)
    Show all 3 references for ABIN967619

  5. Cow (Bovine) Polyclonal RAB27A Primary Antibody for WB - ABIN2786786 : Chiaverini, Beuret, Flori, Busca, Abbe, Bille, Bahadoran, Ortonne, Bertolotto, Ballotti: Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport. in The Journal of biological chemistry 2008 (PubMed)

  6. Rat (Rattus) Polyclonal RAB27A Primary Antibody for IP, WB - ABIN1742353 : de Wit, Walter, Milosevic, Gulyás-Kovács, Riedel, Sørensen, Verhage: Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes. in Cell 2009 (PubMed)

More Antibodies against RAB27A Interaction Partners

Human RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. RAB27A, RAB27B (show RAB27B Antibodies) and VPS36 (show VPS36 Antibodies) are frequently underexpressed in advanced prostate cancer and are inversely correlated with prostate cancer outcome. There seems to be a close relationship in the expression of RAB27A, RAB27B (show RAB27B Antibodies) and VPS36 (show VPS36 Antibodies), with RAB27A and RAB27B (show RAB27B Antibodies) being dependent on VPS36 (show VPS36 Antibodies).

  2. identified small molecule inhibitors of Rab27a-JFC1 (show SYTL1 Antibodies) binding that were also active in cell-based neutrophil-specific exocytosis assays, demonstrating the druggability of Rab (show HRB Antibodies) GTPases and their effectors.

  3. MicroRNA-134-3p is a novel potential inhibitor of human ovarian cancer stem cells by targeting RAB27A.

  4. decreased expression of Rab27A and Rab27B (show RAB27B Antibodies), especially Rab27A, closely correlated with tumor progression and are valuable prognostic indicators in colorectal cancer patients.

  5. We report two unrelated teenagers with hemophagocytic lymphohistiocytosis and an identical heterozygous RAB27A mutation (c.259G-->C).

  6. Data suggest that microRNA miR (show MLXIP Antibodies)-582-5p may function as a tumor suppressor in the development of colorectal carcinoma (CRC (show CALR Antibodies)) by targeting RAS-related GTP-binding protein (show RAB10 Antibodies) (Rab27a), indicating a novel therapeutic strategy for patients with CRC (show CALR Antibodies).

  7. Experimental data are reviewed with a focus on the secretory Rab27 family of small GTPases and their implications in cancer progression.

  8. miR (show MLXIP Antibodies)-122 has a Rab27a-dependent function in the hepatitis C virus lifecycle

  9. Rab27A may be used as a valuable prognostic biomarker for colorectal carcinoma patients.

  10. Our data indicate that RAB27A expression is an independent prognostic marker for pancreatic ductal adenocarcinoma

Mouse (Murine) RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. Loss of Rab3D (show RAB3D Antibodies) from secretory vesicles, leading to disproportionate Rab27-to-Rab3D (show RAB3D Antibodies) activity, may contribute to the enhanced release of cathepsin S (show CTSS Antibodies) in tears of patients with Sjogren's syndrome.

  2. identified small molecule inhibitors of Rab27a-JFC1 (show SYTL1 Antibodies) binding that were also active in cell-based neutrophil-specific exocytosis assays, demonstrating the druggability of Rab (show HRB Antibodies) GTPases and their effectors.

  3. The Rab27A regulates CG exocytosis following MII-stage oocyte activation.

  4. MicroRNA-134-3p is a novel potential inhibitor of human ovarian cancer stem cells by targeting RAB27A.

  5. Given that GTP (show AK3 Antibodies)- and GDP-bound Rab27a regulate exocytosis.

  6. This paper showed an inhibitory effect of Rab27a directly at the pore forming CaV1.3 (show CACNA1D Antibodies) subunit of L-type channels, leading to decreased current density and reduced VEGF-A (show VEGFA Antibodies) secretion by the retinal pigment epithelium.

  7. results show that Rab27A is present in mouse pancreatic acinar cells and mainly regulates secretion through the minor-regulated pathway

  8. Rab27A deficiency shows the increased surface level of c-fms (show CSF1R Antibodies), and the delayed downregulation of RANK in ashen cells, resulting in enhanced signaling of M-CSF (show CSF1R Antibodies) and RANKL (show TNFSF11 Antibodies).

  9. Rab27b (show RAB27B Antibodies) is expressed in bone marrow derived neutrophils and Rab27b (show RAB27B Antibodies) knockout (Rab27b (show RAB27B Antibodies) KO) along with Rab27a/b double knockout (Rab27DKO) neutrophils exhibit impaired transwell migration in vitro in response to chemokines MIP-2 (show CXCL2 Antibodies) and LTB4 (show PTGR1 Antibodies).

  10. Our findings indicate that Slp2-a (show SYTL2 Antibodies) controls renal cell size through regulation of Rap (show LRPAP1 Antibodies)-ezrin (show EZR Antibodies) signaling independently of Rab27.

RAB27A Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Alternative names and synonyms associated with RAB27A

  • RAB27A, member RAS oncogene family (rab27a) antibody
  • RAB27A, member RAS oncogene family (RAB27A) antibody
  • RAB27A, member RAS oncogene family (rab27a-b) antibody
  • RAB27A, member RAS oncogene family (Rab27a) antibody
  • 2210402C08Rik antibody
  • 2410003M20Rik antibody
  • 4933437C11Rik antibody
  • ash antibody
  • GS2 antibody
  • HsT18676 antibody
  • MGC80943 antibody
  • MGC89827 antibody
  • RAB27 antibody
  • RAB27A antibody
  • RAM antibody
  • zgc:114135 antibody

Protein level used designations for RAB27A

RAB27A, member RAS oncogene family , Ras-related protein Rab-27A , rab27a, member ras oncogene family , ras-related protein Rab-27A , GTP-binding protein Ram , rab-27 , member RAS oncogene family, RAB27A , ashen , low Mr GTP-binding protein , ram p25 , RAS oncogene family member

GENE ID SPECIES
444290 Xenopus laevis
453455 Pan troglodytes
493339 Xenopus (Silurana) tropicalis
494641 Xenopus laevis
570907 Danio rerio
5873 Homo sapiens
606749 Sus scrofa
618035 Bos taurus
11891 Mus musculus
50645 Rattus norvegicus
608699 Canis lupus familiaris
415410 Gallus gallus
101086976 Felis catus
101122791 Ovis aries
100720981 Cavia porcellus
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