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Browse our RAB27A (RAB27A) ELISA Kits

Full name:
RAB27A, Member RAS Oncogene Family ELISA Kits (RAB27A)
On www.antibodies-online.com are 1 RAB27A, Member RAS Oncogene Family (RAB27A) ELISA Kits from 1 different suppliers available. Additionally we are shipping RAB27A Antibodies (83) and RAB27A Proteins (16) and many more products for this protein. A total of 103 RAB27A products are currently listed.
Synonyms:
2210402C08Rik, 2410003M20Rik, 4933437C11Rik, ash, GS2, HsT18676, MGC80943, MGC89827, RAB27, RAB27A, RAM, zgc:114135
list all ELISA KIts Gene Name GeneID UniProt
RAB27A 5873 P51159
Mouse RAB27A RAB27A 11891 Q9ERI2
Rat RAB27A RAB27A 50645 P23640

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RAB27A (RAB27A) ELISA Kits by Reactivity

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Human RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. RAB27A, RAB27B (show RAB27B ELISA Kits) and VPS36 (show VPS36 ELISA Kits) are frequently underexpressed in advanced prostate cancer and are inversely correlated with prostate cancer outcome. There seems to be a close relationship in the expression of RAB27A, RAB27B (show RAB27B ELISA Kits) and VPS36 (show VPS36 ELISA Kits), with RAB27A and RAB27B (show RAB27B ELISA Kits) being dependent on VPS36 (show VPS36 ELISA Kits).

  2. identified small molecule inhibitors of Rab27a-JFC1 binding that were also active in cell-based neutrophil-specific exocytosis assays, demonstrating the druggability of Rab (show HRB ELISA Kits) GTPases and their effectors.

  3. MicroRNA-134-3p is a novel potential inhibitor of human ovarian cancer stem cells by targeting RAB27A.

  4. decreased expression of Rab27A and Rab27B (show RAB27B ELISA Kits), especially Rab27A, closely correlated with tumor progression and are valuable prognostic indicators in colorectal cancer patients.

  5. We report two unrelated teenagers with hemophagocytic lymphohistiocytosis and an identical heterozygous RAB27A mutation (c.259G-->C).

  6. Data suggest that microRNA miR (show MLXIP ELISA Kits)-582-5p may function as a tumor suppressor in the development of colorectal carcinoma (CRC (show CALR ELISA Kits)) by targeting RAS-related GTP-binding protein (show RAB10 ELISA Kits) (Rab27a), indicating a novel therapeutic strategy for patients with CRC (show CALR ELISA Kits).

  7. Experimental data are reviewed with a focus on the secretory Rab27 family of small GTPases and their implications in cancer progression.

  8. miR (show MLXIP ELISA Kits)-122 has a Rab27a-dependent function in the hepatitis C virus lifecycle

  9. Rab27A may be used as a valuable prognostic biomarker for colorectal carcinoma patients.

  10. Our data indicate that RAB27A expression is an independent prognostic marker for pancreatic ductal adenocarcinoma

Mouse (Murine) RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. Loss of Rab3D (show RAB3D ELISA Kits) from secretory vesicles, leading to disproportionate Rab27-to-Rab3D (show RAB3D ELISA Kits) activity, may contribute to the enhanced release of cathepsin S (show CTSS ELISA Kits) in tears of patients with Sjogren's syndrome.

  2. identified small molecule inhibitors of Rab27a-JFC1 binding that were also active in cell-based neutrophil-specific exocytosis assays, demonstrating the druggability of Rab (show HRB ELISA Kits) GTPases and their effectors.

  3. The Rab27A regulates CG exocytosis following MII-stage oocyte activation.

  4. MicroRNA-134-3p is a novel potential inhibitor of human ovarian cancer stem cells by targeting RAB27A.

  5. Given that GTP (show AK3 ELISA Kits)- and GDP-bound Rab27a regulate exocytosis.

  6. This paper showed an inhibitory effect of Rab27a directly at the pore forming CaV1.3 (show CACNA1D ELISA Kits) subunit of L-type channels, leading to decreased current density and reduced VEGF-A (show VEGFA ELISA Kits) secretion by the retinal pigment epithelium.

  7. results show that Rab27A is present in mouse pancreatic acinar cells and mainly regulates secretion through the minor-regulated pathway

  8. Rab27A deficiency shows the increased surface level of c-fms (show CSF1R ELISA Kits), and the delayed downregulation of RANK in ashen cells, resulting in enhanced signaling of M-CSF (show CSF1R ELISA Kits) and RANKL (show TNFSF11 ELISA Kits).

  9. Rab27b (show RAB27B ELISA Kits) is expressed in bone marrow derived neutrophils and Rab27b (show RAB27B ELISA Kits) knockout (Rab27b (show RAB27B ELISA Kits) KO) along with Rab27a/b double knockout (Rab27DKO) neutrophils exhibit impaired transwell migration in vitro in response to chemokines MIP-2 (show CXCL2 ELISA Kits) and LTB4 (show PTGR1 ELISA Kits).

  10. Our findings indicate that Slp2-a (show SYTL2 ELISA Kits) controls renal cell size through regulation of Rap (show LRPAP1 ELISA Kits)-ezrin (show EZR ELISA Kits) signaling independently of Rab27.

RAB27A Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Alternative names and synonyms associated with RAB27A

  • RAB27A, member RAS oncogene family (rab27a) Elisa Kit
  • RAB27A, member RAS oncogene family (RAB27A) Elisa Kit
  • RAB27A, member RAS oncogene family (rab27a-b) Elisa Kit
  • RAB27A, member RAS oncogene family (Rab27a) Elisa Kit
  • 2210402C08Rik Elisa Kit
  • 2410003M20Rik Elisa Kit
  • 4933437C11Rik Elisa Kit
  • ash Elisa Kit
  • GS2 Elisa Kit
  • HsT18676 Elisa Kit
  • MGC80943 Elisa Kit
  • MGC89827 Elisa Kit
  • RAB27 Elisa Kit
  • RAB27A Elisa Kit
  • RAM Elisa Kit
  • zgc:114135 Elisa Kit

Protein level used designations for RAB27A

RAB27A, member RAS oncogene family , Ras-related protein Rab-27A , rab27a, member ras oncogene family , ras-related protein Rab-27A , GTP-binding protein Ram , rab-27 , member RAS oncogene family, RAB27A , ashen , low Mr GTP-binding protein , ram p25 , RAS oncogene family member

GENE ID SPECIES
444290 Xenopus laevis
453455 Pan troglodytes
493339 Xenopus (Silurana) tropicalis
494641 Xenopus laevis
570907 Danio rerio
5873 Homo sapiens
606749 Sus scrofa
618035 Bos taurus
11891 Mus musculus
50645 Rattus norvegicus
608699 Canis lupus familiaris
415410 Gallus gallus
101086976 Felis catus
101122791 Ovis aries
100720981 Cavia porcellus
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