Browse our Syntaxin 1A (Brain) Proteins (STX1A)

On are 15 Syntaxin 1A (Brain) (STX1A) Proteins from 8 different suppliers available. Additionally we are shipping Syntaxin 1A (Brain) Antibodies (159) and Syntaxin 1A (Brain) Kits (19) and many more products for this protein. A total of 207 Syntaxin 1A (Brain) products are currently listed.
anon-EST:Gibbs4, anon-WO02059370.54, CG5448, CG10716, CG18615, CG31136, CT30033, Dmel\\CG31136, Dm Syx1, DmSyx1A, dSyx1, HPC-1, l(3)06737, P35-1, STX1, STX1A, sx1a, SYN1A, synt, syntaxin1a, syt-1A, Syt1A, syx, syx-1, syx-1A, syx1, syx1A, SyxA
list all proteins Gene Name GeneID UniProt
STX1A 6804 Q16623
STX1A 116470 P32851
STX1A 20907 O35526

Syntaxin 1A (Brain) Proteins (STX1A) by Origin

More Proteins for Syntaxin 1A (Brain) Interaction Partners

Fruit Fly (Drosophila melanogaster) Syntaxin 1A (Brain) (STX1A) interaction partners

  1. The authors found two syntaxin1A mutations that confer opposite general anesthesia phenotypes

  2. Data suggest that Ca(2 (show CA2 Proteins)+)-CaM (show CALM Proteins) regulation of V100 may control SNARE (show NAPA Proteins) complex assembly for a subset of synaptic vesicles that sustain spontaneous release.

  3. these results indicate that SNAP-25 (show SNAP25 Proteins)-R206 and syntaxin (show STX4 Proteins)-D253 play a major role in neuroexocytosis and support a radial assembly of several SNARE (show NAPA Proteins) complexes interacting via the ionic couple formed by these two residues.

  4. Syntaxin1A domain formation is induced by phosphoinositide-3,4,5-triphosphate; this clustering is dependent on positively charged residues in the juxtamembrane domain.

  5. The Syx1A dependent trafficking of Grk (show GRK4 Proteins) protein is required for efficient EGFR (show EGFR Proteins) signaling during dorsal-ventral patterning.

  6. analysis of epistatic interactions related to mutation of Syx1A

  7. Syntaxin 1A molecules share a conserved threonine in C-terminal +7 layer near transmembrane domain. Mutation of threonine to isoleucine results in a structural change that resembles those found in syntaxins ascribed to the constitutive secretory pathway

Human Syntaxin 1A (Brain) (STX1A) interaction partners

  1. Our results suggest that, as in the CNS, CADM1 interactions drive exocytic site assembly and promote actin network formation. These results support the broader hypothesis that the effects of cell-cell contact on beta-cell maturation and function are mediated by the same extracellular protein interactions that drive the formation of the presynaptic exocytic machinery. These interactions may be therapeutic targets for re...

  2. A significant interactive two-locus model of STX1A_rs4363087|VAMP2_rs2278637 (presynaptic genes) was observed among SVC (show COL4A1 Proteins) variants in all epilepsy cases.

  3. Mislocalization of syntaxin-1 was found in pluripotent stem cells from epileptic encephalopathy patient.

  4. Blockade of the SNARE (show NAPA Proteins) protein syntaxin 1 inhibits glioblastoma tumor growth.

  5. SNARE (show NAPA Proteins) complex genes and their interactions may play a significant role in susceptibility and working memory of ADHD.

  6. We described clinical, genetic, and functional data from 17 families with a diagnosis of benign familial neonatal epilepsy caused by KCNQ2 (show KCNQ2 Proteins) or KCNQ3 mutations and we showed that some mutations lead to a reduction of Q2 channel regulation by syntaxin-1A.

  7. no associaton with idiopathic generalized epilepsy was found regarding Intron 7 rs1569061 of Syntaxin 1A gene, MnlI rs3746544 and DdeI rs1051312 polymorphisms of SNAP-25 (show SNAP25 Proteins) gene compared with healthy subjects

  8. The clinical relevance of STX1A variants in CF

  9. PIP2 affects islet beta-cell KATP channels not only by its actions on Kir6.2 but also by sequestering Syn-1A to modulate Syn-1A availability and its interactions with SUR1 on PM.

  10. Prefusion structure of syntaxin-1A suggests pathway for folding into neuronal trans-SNARE (show NAPA Proteins) complex fusion intermediate.

Mouse (Murine) Syntaxin 1A (Brain) (STX1A) interaction partners

  1. proteins, such as syntaxin-1, Munc18-1, or SNAP-25, modulate alpha-synuclein neuropathy and/or are dysregulated in Alzheimer's disease, understanding this type of neurodegeneration may provide new links between synaptic defects and neurodegeneration in humans

  2. Therefore, our work provides insights into differential functions of Stx1 in neuronal maintenance and neurotransmission, with the latter explored further into its functions in vesicle docking and fusion.

  3. Syn (show SYP Proteins)-1A actions on newcomer SGs (show SKI Proteins) were partly mediated by Syn (show SYP Proteins)-1A interactions with newcomer SG VAMP8 (show VAMP8 Proteins)

  4. The results of this study suggested that STX1A plays an important role in social behavior through regulation of the OXTergic neural system.

  5. Data suggest that porosome-associated proteins SNAP25 (show SNAP25 Proteins), TREK-1 (show KCNK2 Proteins), syntaxin-1A, and Gai3 exhibit stability and functionality such that isolated proteins can be reconstituted as insulin (show INS Proteins)-secreting porosomes in cell membrane of live cells.

  6. syntaxin 1 and vesicle-associated membrane protein 1 (show VAMP1 Proteins) are more suitable targets to abolish functional soluble N-ethylmaleimide-sensitive factor attachment protein receptor (show VTI1B Proteins) complexes

  7. Data show a significant increase of vesicle-associated membrane protein 2 (VAMP-2 (show VAMP2 Proteins)) mRNA expression, however, the expressions of synaptosome-associated protein of 25 kDa (SNAP-25 (show SNAP25 Proteins)) and syntaxin 1A did not exhibit the changes in hippocampus.

  8. Although STX1A and STX1B (show STX1B Proteins) share a basic function as neuronal t-SNAREs, STX1B (show STX1B Proteins) but not STX1A is necessary for the regulation of spontaneous and evoked synaptic vesicle exocytosis in fast transmission.

  9. we found that STX1A and STX1B (show STX1B Proteins) play distinct roles in neuronal survival using

  10. point mutation in syntaxin-1A causes abnormal regulation of neuronal plasticity and vesicle recycling and that the affected syntaxin-1A/CaMKII (show CAMK2G Proteins) interaction is essential for normal brain and synaptic functions in vivo.

Cow (Bovine) Syntaxin 1A (Brain) (STX1A) interaction partners

  1. Syntaxin 1A drives fusion of large dense-core neurosecretory granules into a planar lipid bilayer

  2. microdomains carrying syntaxin1/SNAP-25 (show SNAP25 Proteins) and different types of calcium channels act as the sites for physiological granule fusion in "in situ" chromaffin cells

Syntaxin 1A (Brain) (STX1A) Protein Profile

Protein Summary

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE

Alternative names and synonyms associated with Syntaxin 1A (Brain) (STX1A)

  • Syntaxin 1A (Syx1A)
  • syntaxin-1A-like (LOC100061863)
  • syntaxin 1A (brain) (STX1A)
  • syntaxin 1A (brain) (stx1a)
  • syntaxin-1A (EDI_005240)
  • syntaxin-1A (Tsp_07354)
  • syntaxin 1A (brain) (Stx1a)
  • syntaxin-1A-like (LOC100512594)
  • syntaxin-1A-like (LOC100855965)
  • anon-EST:Gibbs4 protein
  • anon-WO02059370.54 protein
  • CG5448 protein
  • CG10716 protein
  • CG18615 protein
  • CG31136 protein
  • CT30033 protein
  • Dmel\\CG31136 protein
  • Dm Syx1 protein
  • DmSyx1A protein
  • dSyx1 protein
  • HPC-1 protein
  • l(3)06737 protein
  • P35-1 protein
  • STX1 protein
  • STX1A protein
  • sx1a protein
  • SYN1A protein
  • synt protein
  • syntaxin1a protein
  • syt-1A protein
  • Syt1A protein
  • syx protein
  • syx-1 protein
  • syx-1A protein
  • syx1 protein
  • syx1A protein
  • SyxA protein

Protein level used designations for Syntaxin 1A (Brain) Proteins (STX1A)

CG31136-PA , CG31136-PB , Dsyntaxin-1A , STX1A , Syx1A-PA , Syx1A-PB , syntaxin , syntaxin 1 , syntaxin 1A , syntaxin-1 , syntaxin-1A , syntaxin1 , syntaxin1A , syntx 1 , syntaxin 1A (brain) , neuron-specific antigen HPC-1 , P35A , synaptotagmin-associated 35 kDa protein , syntaxin 1A (brain)-like , syntaxin 1 a

42854 Drosophila melanogaster
100061863 Equus caballus
742605 Pan troglodytes
779637 Xenopus (Silurana) tropicalis
100173962 Pongo abelii
5880118 Entamoeba dispar SAW760
10898477 Trichinella spiralis
6804 Homo sapiens
116470 Rattus norvegicus
20907 Mus musculus
788566 Bos taurus
770216 Gallus gallus
607840 Canis lupus familiaris
100727115 Cavia porcellus
100512594 Sus scrofa
100855965 Canis lupus familiaris
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