ADAM Metallopeptidase Domain 10 (ADAM10) (C-Term) Peptide

Details for Product No. ABIN1003726, Supplier: Log in to see
Protein Name
  • adam10
  • wu:fc03d12
  • ADAM10
  • LOC100219653
  • Adam10
  • 1700031C13Rik
  • MADM
  • kuz
  • kuzbanian
  • AD10
  • CD156c
  • HsT18717
  • ad10
  • cd156c
  • madm
  • xadam10
  • ADAM-10
  • ADAM 10
  • a disintegrin and metalloprotease domain 10a
  • ADAM metallopeptidase domain 10
  • a disintegrin and metallopeptidase domain 10
  • ADAM10
  • adam10a
  • ADAM10
  • LOC100219653
  • Adam10
  • adam10
  • LOC100101614
Protein Region
C-Term
Application
Western Blotting (WB)
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Blocked Antibody anti-ADAM17 antibody (ADAM Metallopeptidase Domain 17) (C-Term) (ABIN1003301)
Characteristics 17 amino acids near the carboxy terminus of human ADAM10.
Application Notes ADAM10 peptide is used for blocking the activity of Anti-ADAM10 . Incubating the peptide with equal volume of ADAM10 antibody for 30 min at 37ºC usually completely blocks the antibody activity in Western blotting.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Background publications Cecconi, Alvarez-Bolado, Meyer, Roth, Gruss: "Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development." in: Cell, Vol. 94, Issue 6, pp. 727-37, 1998 (PubMed).

Hu, Benedict, Wu, Inohara, Núñez: "Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 8, pp. 4386-91, 1998 (PubMed).

Zou, Henzel, Liu, Lutschg, Wang: "Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3." in: Cell, Vol. 90, Issue 3, pp. 405-13, 1997 (PubMed).

Li, Nijhawan, Budihardjo, Srinivasula, Ahmad, Alnemri, Wang: "Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade." in: Cell, Vol. 91, Issue 4, pp. 479-89, 1997 (PubMed).