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SIRP alpha (C-Term) Peptide

Details for Product No. ABIN1003868, Supplier: Log in to see
Protein Name
Protein Region
C-Term
Application
Western Blotting (WB)
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Blocked Antibody anti-SIRPalpha (Tyrosine Kinase Substrate) (C-Term) antibody (ABIN1003137)
Characteristics 17 amino acids near the carboxy terminus of human SIRP alpha.
Application Notes SIRP alpha peptide is used for blocking the activity of Anti-SIRP alpha . Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks the antibody activity in Western blotting.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Marsters, Sheridan, Donahue, Pitti, Gray, Goddard, Bauer, Ashkenazi: "Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B." in: Current biology : CB, Vol. 6, Issue 12, pp. 1669-76, 1997

Bodmer, Burns, Schneider, Hofmann, Steiner, Thome, Bornand, Hahne, Schröter, Becker, Wilson, French, Browning, MacDonald, Tschopp: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." in: Immunity, Vol. 6, Issue 1, pp. 79-88, 1997

Background publications Kitson, Raven, Jiang, Goeddel, Giles, Pun, Grinham, Brown, Farrow: "A death-domain-containing receptor that mediates apoptosis." in: Nature, Vol. 384, Issue 6607, pp. 372-5, 1996