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T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (C-Term) Peptide

Details for Product No. ABIN1003890, Supplier: Log in to see
Protein Name
  • B430010N18Rik
  • MGC99322
  • RGD1564516
  • SMUCKLER
  • TIM-4
  • Tim4
  • TIM4
  • TIMD4
Protein Region
C-Term
Application
Western Blotting (WB)
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Blocked Antibody anti-T-Cell Immunoglobulin & Mucin Domain Containing Protein 4 (C-Term) antibody (ABIN1003242)
Characteristics 15 amino acids near the carboxy terminus of human TIM-4.
Application Notes TIM-4 peptide is used for blocking activity of TIM-4 antibody . It usually blocks antibody activity completely in Western blot by incubating peptide with equal volume of antibody for 30 min at 37?C.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Wiley, Winkles: "TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor." in: Cytokine & growth factor reviews, Vol. 14, Issue 3-4, pp. 241-9, 2003 (PubMed).

Background publications Chicheportiche, Chicheportiche, Sizing, Thompson, Benjamin, Ambrose, Dayer: "Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies." in: Arthritis research, Vol. 4, Issue 2, pp. 126-33, 2002 (PubMed).

Lynch, Wang, Lund, Chen, Leal, Wiley: "TWEAK induces angiogenesis and proliferation of endothelial cells." in: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8455-9, 1999 (PubMed).

Chicheportiche, Bourdon, Xu, Hsu, Scott, Hession, Garcia, Browning: "TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32401-10, 1998 (PubMed).