Tuberous Sclerosis 2 (TSC2) (C-Term) Peptide

Details for Product No. ABIN1003910
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Protein Name
Synonyms TSC2, fc16b02, tuberin, wu:fc16b02, LAM, TSC4, Nafld, Tcs2, Rc
Protein Region
C-Term
Application
Western Blotting (WB)
Pubmed 4 references available
Quantity 50 μg
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Catalog No. ABIN1003910
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Characteristics 15 amino acids near the carboxy terminus of human TSC2.
Alternative Name TSC2 / Tuberin
Application Notes TSC2 peptide is used for blocking the activity of the Anti-TSC2 antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Juan, McNiece, Argento et al.: "Identification and mapping of Casp7, a cysteine protease resembling CPP32 beta, interleukin-1 beta converting enzyme, and CED-3." in: Genomics, Vol. 40, Issue 1, pp. 86-93, 1997 (PubMed).

Wolf, Green: "Suicidal tendencies: apoptotic cell death by caspase family proteinases." in: The Journal of biological chemistry, Vol. 274, Issue 29, pp. 20049-52, 1999 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005 (PubMed).

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