Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (Internal Region) Peptide

Details for Product No. ABIN1004041, Supplier: Log in to see
Protein Name
  • mal
  • wyatt
  • BACTS1
  • Mal
  • MyD88-2
  • AA407980
  • C130027E04Rik
  • Tlr4ap
  • Wyatt
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein
  • toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  • tirap
  • TIRAP
  • Tirap
Protein Region
Internal Region
Application
Western Blotting (WB)
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Blocked Antibody anti-TIRAP antibody (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein) (Internal Region) (ABIN1003283)
Characteristics 20 amino acids near the center of human TIRAP.
Application Notes TIRAP peptide is used for blocking the activity of TIRAP antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Background publications Cotteret, Jaffer, Beeser, Chernoff: "p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD." in: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5526-39, 2003 (PubMed).

Abo, Qu, Cammarano, Dan, Fritsch, Baud, Belisle, Minden: "PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia." in: The EMBO journal, Vol. 17, Issue 22, pp. 6527-40, 1999 (PubMed).

Product cited in: Jaffer, Chernoff: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, 2002 (PubMed).