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Toll-Like Receptor 1 (TLR1) (Internal Region) Peptide

Details for Product No. ABIN1004042, Supplier: Log in to see
Protein Name
  • CD281
  • rsc786
  • TIL
  • TIL. LPRS5
Protein Region
Internal Region
Application
Western Blotting (WB)
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Blocked Antibody anti-TLR1 antibody (Toll-Like Receptor 1) (Internal Region) (ABIN1003316)
Characteristics 17 amino acids near the center of human TLR1.
Application Notes TLR1 peptide is used for blocking the activity of TLR1 antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Gaur, Aggarwal: "Regulation of proliferation, survival and apoptosis by members of the TNF superfamily." in: Biochemical pharmacology, Vol. 66, Issue 8, pp. 1403-8, 2003

Ronchetti, Nocentini, Riccardi, Pandolfi: "Role of GITR in activation response of T lymphocytes." in: Blood, Vol. 100, Issue 1, pp. 350-2, 2002

Gurney, Marsters, Huang, Pitti, Mark, Baldwin, Gray, Dowd, Brush, Heldens, Schow, Goddard, Wood, Baker, Godowski, Ashkenazi: "Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR." in: Current biology : CB, Vol. 9, Issue 4, pp. 215-8, 1999

Background publications Shimizu, Yamazaki, Takahashi, Ishida, Sakaguchi: "Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance." in: Nature immunology, Vol. 3, Issue 2, pp. 135-42, 2002