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C-C Chemokine Receptor Type 5 (CCR5) (N-Term) Peptide

Details for Product No. ABIN1004114, Supplier: Log in to see
Protein Name
  • AM4-7
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CCR5
  • CD195
  • CKR-5
  • CKR5
  • Ckr5
  • CMKBR5
  • Cmkbr5
  • GPCR
  • IDDM22
Protein Region
Western Blotting (WB)
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Blocked Antibody anti-CC-Chemokine Receptor 5 (HIV & Chemokine Receptor) (N-Term) antibody (ABIN1002065)
Characteristics 15 amino amino terminus of human CCR5.
Research Area Chemokines, Receptors, CD Antigens
Application Notes CCR5 peptide is used for blocking the activity of Anti-CCR5 . Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks the activity of Anti-CCR5 in Western blotting.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Background publications He, Chen, Farzan, Choe, Ohagen, Gartner, Busciglio, Yang, Hofmann, Newman, Mackay, Sodroski, Gabuzda: "CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia." in: Nature, Vol. 385, Issue 6617, pp. 645-9, 1997

Deng, Liu, Ellmeier, Choe, Unutmaz, Burkhart, Di Marzio, Marmon, Sutton, Hill, Davis, Peiper, Schall, Littman, Landau: "Identification of a major co-receptor for primary isolates of HIV-1." in: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996

Choe, Farzan, Sun, Sullivan, Rollins, Ponath, Wu, Mackay, LaRosa, Newman, Gerard, Gerard, Sodroski: "The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates." in: Cell, Vol. 85, Issue 7, pp. 1135-48, 1996

Feng, Broder, Kennedy, Berger: "HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 272, Issue 5263, pp. 872-7, 1996