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Lymphocyte Antigen 86 (LY86) Peptide

Details for Product No. ABIN1004395, Supplier: Log in to see
Protein Name
  • LY86
  • MGC157074
  • MD-1
  • MMD-1
  • dJ80N2.1
  • MD1
  • BPAD
Application
Western Blotting (WB)
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Blocked Antibody anti-Lymphocyte Antigen 86 (LY86) (Internal Region) antibody (ABIN1002833)
Characteristics 15 amino acids near the center of human MD-1.
Application Notes MD-1 peptide is used for blocking the activity of MD-1 antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Lockshin, Osborne, Zakeri: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, 2000 (PubMed).

Background publications Takahashi, Karbowski, Yamaguchi et al.: "Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9369-82, 2005 (PubMed).

Cuddeback, Yamaguchi, Komatsu et al.: "Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20559-65, 2001 (PubMed).

Oltvai, Milliman, Korsmeyer: "Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death." in: Cell, Vol. 74, Issue 4, pp. 609-19, 1993 (PubMed).